(1) The nuclear origin of the Ha antigen was confirmed by the speckled nuclear immunofluorescence staining pattern given by purified antibody to Ha obtained from a specific immune precipitate.
(2) The Fc fragment of this protein reacted with and was solubilized by the staphylococcal A protein which also precipitated the intact immunoglobulin.
(3) It could be demonstrated by radioimmune precipitation of virus labeled with[35S]methionine that all three polypeptides are specific for hog cholera virions.
(4) Nine of the in vivo synthesized early polypeptides can be precipitated specifically from infected cell extracts by antisera with specificity against early adenovirus proteins.
(5) Its pathogenesis, still incompletely elucidated, involves the precipitation of immune complexes in the walls of the all vessels.
(6) The usefulness of the proposed method is obvious in cases where the composition of a precipitate on LM scale is to be compared with the LM appearance of the surrounding tissue.
(7) After precipitation of plasma proteins by addition of methanol the samples are injected directly into the liquid chromatographic system.
(8) Thus Sephadex chromatography of the solution obtained by dissolving the antigen-antibody precipitate in these media repeatedly gave two peaks corresponding to anti-ovalbumin and ovalbumin.
(9) When AMT administration was discontinued 40 hrs before precipitation of withdrawal the withdrawal pattern occurred with unchanged intensity.
(10) Using a simple precipitation technique we observed that the serum concentrations of low density lipoproteins in healthy Africans were less than half the serum concentrations in healthy Europeans.
(11) There was no correlation between anti-TNP-precipitating antibody titer after sensitization and the ability to respond to challenge by hapten-heterologous carrier.
(12) Precipitating antibodies were found in both lines; they first appeared 7 days after inoculation in P-line birds and 14 days after inoculation in N-line birds, but thereafter there was no difference between the two genetic lines.
(13) The new technique, Surface Immune Precipitation (SIP), entails the application of an antigen sample droplet directly onto the surface of a gel containing antibody, the gel being supported by a reflecting substrate.
(14) In this study we have compared purified C4A and C4B with regard to their ability to prevent immune complex precipitation and to enhance the binding of both preformed and nascent immune complexes to the receptor CR1 on red cells.
(15) A lesser inhibitory effect (a decrease in the rate of precipitation) was observed when gallbladder bile was diluted but was lost after 10-fold dilution.
(16) The first step is the preparation of a globulin-enriched fraction by precipitation with ammonium sulfate at 50% saturation, or of an immune-complex-enriched fraction by precipitation with 5% polyethylene glycol 6000.
(17) DNase I microspheres were then introduced into the extracorporeal circuit which resulted in an acceleration of degradation of acid precipitable 125I-nDNA.
(18) The dramatic nationwide increase of primary and secondary syphilis in women has precipitated a dramatic rise in congenital syphilis.
(19) The translation of mRNA for S-adenosylmethionine decarboxylase was studied using a polyamine-depleted reticulocyte lysate supplemented with mRNA from rat prostate and the antiserum to precipitate the proteins corresponding to S-adenosylmethionine decarboxylase.
(20) Only heart rate correlated closely with the precipitation of angina.
Steep
Definition:
(a.) Bright; glittering; fiery.
(v. t.) To soak in a liquid; to macerate; to extract the essence of by soaking; as, to soften seed by steeping it in water. Often used figuratively.
(v. i.) To undergo the process of soaking in a liquid; as, the tea is steeping.
(n.) Something steeped, or used in steeping; a fertilizing liquid to hasten the germination of seeds.
(n.) A rennet bag.
(v. t.) Making a large angle with the plane of the horizon; ascending or descending rapidly with respect to a horizontal line or a level; precipitous; as, a steep hill or mountain; a steep roof; a steep ascent; a steep declivity; a steep barometric gradient.
(v. t.) Difficult of access; not easy reached; lofty; elevated; high.
(v. t.) Excessive; as, a steep price.
(n.) A precipitous place, hill, mountain, rock, or ascent; any elevated object sloping with a large angle to the plane of the horizon; a precipice.
Example Sentences:
(1) The dose response effect in this tumor is steep and combinations which compromise the dose of adriamycin too greatly are showing inferior results.
(2) Steep longitudinal and transverse gradients of glycogen are known to exist in the organ of Corti of the guinea pig, with preferential accumulation in the outer hair cells of the apical turns.
(3) The steep portion of the relationship between Retzius cell action potential amplitude and membrane potential extrapolated to an apparent reversal potential of -13 mV.
(4) This property of endotoxin can serve as a sensitive bioassay, although the dose-response curve is steep.
(5) With its steep hills and cobblestones, the neighbourhood of São Cristóvão in Ouro Preto isn’t an easy place to play football.
(6) Four patients with herpes zoster ophthalmicus developed peripheral corneal ulcers with steep central edges.
(7) The results showed that measurements of impression profiles and SEM photogrammetry gave the most accurate results adjacent to regions simulating steep cavity margins, whereas the profilometric technique gave erroneous results in these regions.
(8) The intensity dependence of the early ganglion cell discharge, its latency and initial impulse frequency, is shown to follow from such a waveform, assuming that 1) latency L = l + D, where l is the time it takes for the rod response linearly summed over the ganglion cell's receptive field to reach a criterion amplitude, and D is a constant delay; and 2) the initial frequency (below saturation) is proportional to the steepness of rise of the summed rod response at time l. It is shown that the intensity dependences of 1) human visual latency and 2) brightness sensation, including effects of stimulus area and duration, are accounted for by the same model.
(9) The new protocol (standardised exponential exercise protocol, STEEP) is suitable for use on either a treadmill or a bicycle ergometer.
(10) Based on the signals observed by organ absorbance spectrophotometry from two compartments with oxidases of markedly different O2 sensitivity, the mitochondria and the peroxisomes, a distribution between high O2 and zero O2 zones is postulated, an intermediate border zone of O2 concentrations between the K0,5 (O2) values being virtually absent (steep intercellular O2 gradients).
(11) A man who had been near them reached the hotel terrace first, scrambling up a steep sandy bank.
(12) Patients with steep sloping audiograms understand better and patients with a conductive hearing loss component understand less in noisy circumstances with a hearing aid.
(13) The operational values are useful in characterising the steepness of dose-incidence curves for normal tissue injury after different fractionation schedules.
(14) Scarborough council said leaving the houses standing could cause a domino-effect down the steep slope above the picturesque harbour where the explorer Captain James Cook lodged and learned his seafaring skills.
(15) It is shown that this individual exhibits approximate alignment of her photoreceptors with the center of the retinal sphere, clear evidence of side lobes on functions, and surprisingly steep SCE I functions.
(16) For cross-linked alpha alpha, however, the curve sags at temperatures somewhat below the region of principal cooperative loss of helix, the latter occurring at higher temperature but with the same steepness as in the non-cross-linked case.
(17) A reduced venous compliance (VC) and inadequate venoconstriction may impair hemodynamics during hemodialysis, the first by impairing plasma volume preservation and by inducing a steep fall in central venous pressure (CVP) during minor plasma volume loss, the second by inadequate mobilization of hemodynamically inactive blood volume.
(18) A generally similar pattern is seen in healthy controls and in patients with untreated pulmonary tuberculosis, treated leprosy, haemophilia A and chronic obstructive lung disease (COLD) patients treated with prednisolone, but the gradient of increasing CD4:CD8 ratio with depth into the dermis is significantly less steep in patients with tuberculosis, haemophilia and prednisolone-treated COLD than in the healthy controls.
(19) Some problem drugs may be recognized if they display one or more of the following characteristics: narrow therapeutic index, steep dose-effect relationship, nonlinear kinetics, variable bioavailability, and pharmacogenetically determined kinetics.
(20) Replacement of a half of Ca++ ions by Sr++ resulted in an augmentation of steepness of the dependence on sum of [Ca++] and [Sp++], and in a more prominent fall in relaxation velocity as compared with contraction velocity.