(v.) That which pricks, penetrates, or punctures; a sharp and slender thing; a pointed instrument; a goad; a spur, etc.; a point; a skewer.
(v.) The act of pricking, or the sensation of being pricked; a sharp, stinging pain; figuratively, remorse.
(v.) A mark made by a pointed instrument; a puncture; a point.
(v.) A point or mark on the dial, noting the hour.
(v.) The point on a target at which an archer aims; the mark; the pin.
(v.) A mark denoting degree; degree; pitch.
(v.) A mathematical point; -- regularly used in old English translations of Euclid.
(v.) The footprint of a hare.
(v.) A small roll; as, a prick of spun yarn; a prick of tobacco.
(n.) To pierce slightly with a sharp-pointed instrument or substance; to make a puncture in, or to make by puncturing; to drive a fine point into; as, to prick one with a pin, needle, etc.; to prick a card; to prick holes in paper.
(n.) To fix by the point; to attach or hang by puncturing; as, to prick a knife into a board.
(n.) To mark or denote by a puncture; to designate by pricking; to choose; to mark; -- sometimes with off.
(n.) To mark the outline of by puncturing; to trace or form by pricking; to mark by punctured dots; as, to prick a pattern for embroidery; to prick the notes of a musical composition.
(n.) To ride or guide with spurs; to spur; to goad; to incite; to urge on; -- sometimes with on, or off.
(n.) To affect with sharp pain; to sting, as with remorse.
(n.) To make sharp; to erect into a point; to raise, as something pointed; -- said especially of the ears of an animal, as a horse or dog; and usually followed by up; -- hence, to prick up the ears, to listen sharply; to have the attention and interest strongly engaged.
(n.) To render acid or pungent.
(n.) To dress; to prink; -- usually with up.
(n.) To run a middle seam through, as the cloth of a sail.
(n.) To trace on a chart, as a ship's course.
(n.) To drive a nail into (a horse's foot), so as to cause lameness.
(n.) To nick.
(v. i.) To be punctured; to suffer or feel a sharp pain, as by puncture; as, a sore finger pricks.
(v. i.) To spur onward; to ride on horseback.
(v. i.) To become sharp or acid; to turn sour, as wine.
(v. i.) To aim at a point or mark.
Example Sentences:
(1) These results have implications in utilizing codeine phosphate as a positive skin prick test control for allergy testing.
(2) The diagnosis of occupational allergy was based on history, skin prick tests and RAST to the pollen.
(3) Prick tests performed on 16 different condom brands showed that 4 brands caused positive reactions in 52-67% of patients.
(4) One hundred and forty-four had non-allergic and 69 allergic asthma verified retrospectively by positive skin prick test in 1988.
(5) The results of this investigation are clearly in contrast to earlier earlier reports, in that there was a very good correlation between prick test, RAST and case history.
(6) The prick tests, using both commercial allergens and specific extracts prepared from the most common types of coffee and their corresponding sacks, confirmed a sensitization in 21 workers (9.6%).
(7) There were statistically significant exposure-response relations between exposure and symptoms from eyes and upper airways, dry cough, positive skin prick test, and specific IgE and IgG antibodies.
(8) The effect of 4.4 mg azelastine administered orally on airway responsiveness, skin prick testing, daily peak expiratory flow rates and symptoms of asthma was compared with placebo in a 7 week double-blind, parallel group study of 24 patients with extrinsic asthma.
(9) Subjective pain ratings of mucosal pin-prick decreased a surprisingly small degree after application of both solutions.
(10) Having said that, though, the man is clearly a bit of a prick and one with a serial addiction to publicity."
(11) In allergologic out-patient departments of Dubrovnik, Split, Sibenik, Zadar, Pula and Rijeka, 300 patients with pollinosis have been tested by the application of the prick method of group allergens of grass, tree and weed pollen, particularly of Parietariae (pellitory) pollen.
(12) In comparison with conventional allergen preparations immunologically characterized allergens were tested by skin-prick-tests for reactions.
(13) Exclusion of asthmatics and taking into account smoking and skin prick test positivity yielded mostly similar results.
(14) The results of the Phadezym-RAST and IgE-Quick correlated very well (r = 0.96) and both in-vitro methods corresponded to the Skin-Prick-Test (greater than 90%).
(15) Throughout history there have been periods of wild exuberance followed by the pricking of bubbles.
(16) By skin prick testing comparable results were obtained with both extracts.
(17) In both groups of patients, there was a low incidence of the causes of post-cordotomy pain recurrence contralateral to the lesion, i.e., deafferentation pain, fading of analgesia, and pain above the levels up to which deep pin-prick analgesia had been obtained.
(18) In making a computerized cephalometric analysis, first the film should be traced, and the landmarks pricked and manually digitalized into an X-Y coordinate system.
(19) Sections of eggs, fixed 20 to 60 s following fertilization or pricking, show that the tubular cisternae have disappeared and the clusters of cisternae have opened to give rise to longer cisternae arranged in chains.
(20) Bronchial responsiveness to histamine and skin prick test reactions to airborne allergens were measured in a random population sample of 891 adults and 1293 schoolchildren.
Sharp
Definition:
(superl.) Having a very thin edge or fine point; of a nature to cut or pierce easily; not blunt or dull; keen.
(superl.) Terminating in a point or edge; not obtuse or rounded; somewhat pointed or edged; peaked or ridged; as, a sharp hill; sharp features.
(superl.) Affecting the sense as if pointed or cutting, keen, penetrating, acute: to the taste or smell, pungent, acid, sour, as ammonia has a sharp taste and odor; to the hearing, piercing, shrill, as a sharp sound or voice; to the eye, instantaneously brilliant, dazzling, as a sharp flash.
(superl.) High in pitch; acute; as, a sharp note or tone.
(superl.) Raised a semitone in pitch; as, C sharp (C/), which is a half step, or semitone, higher than C.
(superl.) So high as to be out of tune, or above true pitch; as, the tone is sharp; that instrument is sharp. Opposed in all these senses to flat.
(superl.) Very trying to the feelings; piercing; keen; severe; painful; distressing; as, sharp pain, weather; a sharp and frosty air.
(superl.) Cutting in language or import; biting; sarcastic; cruel; harsh; rigorous; severe; as, a sharp rebuke.
(superl.) Of keen perception; quick to discern or distinguish; having nice discrimination; acute; penetrating; sagacious; clever; as, a sharp eye; sharp sight, hearing, or judgment.
(superl.) Eager in pursuit; keen in quest; impatient for gratification; keen; as, a sharp appetite.
(superl.) Keenly or unduly attentive to one's own interest; close and exact in dealing; shrewd; as, a sharp dealer; a sharp customer.
(superl.) Composed of hard, angular grains; gritty; as, sharp sand.
(superl.) Steep; precipitous; abrupt; as, a sharp ascent or descent; a sharp turn or curve.
(superl.) Uttered in a whisper, or with the breath alone, without voice, as certain consonants, such as p, k, t, f; surd; nonvocal; aspirated.
(adv.) To a point or edge; piercingly; eagerly; sharply.
(adv.) Precisely; exactly; as, we shall start at ten o'clock sharp.
(n.) A sharp tool or weapon.
(n.) The character [/] used to indicate that the note before which it is placed is to be raised a half step, or semitone, in pitch.
(n.) A sharp tone or note.
(n.) A portion of a stream where the water runs very rapidly.
(n.) A sewing needle having a very slender point; a needle of the most pointed of the three grades, blunts, betweens, and sharps.
(n.) Same as Middlings, 1.
(n.) An expert.
(v. t.) To sharpen.
(v. t.) To raise above the proper pitch; to elevate the tone of; especially, to raise a half step, or semitone, above the natural tone.
(v. i.) To play tricks in bargaining; to act the sharper.
(v. i.) To sing above the proper pitch.
Example Sentences:
(1) Basal 20 alpha DHP levels remained low until a sharp rise at mid pro-oestrus.
(2) Whole-virus vaccines prepared by Merck Sharp and Dohme (West Point, Pa.) and Merrell-National Laboratories (Cincinnati, Ohio) and subunit vaccines prepared by Parke, Davis and Company (Detroit, Mich.) and Wyeth Laboratories (Philadelphia, Pa.) were given intramuscularly in concentrations of 800, 400, or 200 chick cell-agglutinating units per dose.
(3) Gonadectomy of females was accompanied by changes in the activity of individual HAS links in different direction--some reduction of ACTH in the hypophysis, a sharp and significant fall of the peripheral blood glucocorticoid level and a marked significant elevation of hydrococortisone production in the adrenal cortex in vitro.
(4) The University of the Arts London and Sunderland, Sheffield Hallam, Manchester Met and Leeds Met university have also experienced sharp declines in applications.
(5) A sharp decrease in oxygen uptake occurred in Neurospora crassa cells that were transferred from 30 degrees C to 45 degrees C, and the respiration that resumed later at 45 degrees C was cyanide-insensitive.
(6) In contrast to findings in the rat and dog, no sharp drop but a gradual fall in CLi was observed at decreasing FENa values down to 0.02%.
(7) A more specific differentiation, as indicated by the sharp increase in GAD levels which was concurrent with an increase in interneuronal contacts, lagged behind the initial growth.
(8) It appears that the decline in plasma IGF-I lags considerably behind the sharp fall in plasma GH levels and expression of hepatic IGF-I mRNA.
(9) Supplementation of Mg resulted in a sharp increase in serum PTH level with a rapid disappearance of the dissociation between the two immunoassays of PTH.
(10) A.CA animals were extremely susceptible, showing a sharp and sustained increase in parasitemia starting on day 12, followed by death no later than day 15 post-inoculation.
(11) There was a sharp transition with actin nearly saturated with S1: when the S1 to actin ratio was low, the kinetics were fast (K1 greater than 300 microM, k2 greater than 40 s-1); when it was high, they were slow (K1 = 14 microM, k2 = 2 s-1).
(12) Low calcium causes an increase in optimum frequency, a decrease in current threshold, and an increase in sharpness of tuning in both real axons and axons computed according to the Hodgkin-Huxley formulation; high calcium causes opposite effects.
(13) The Tea Party movement has turned climate denial into a litmus test of conservative credentials – and that has made climate change one of the most sharp divisions between Obama and Romney.
(14) The presence in lamprey kidney of a loop which is similar to Henle's loop in mammals and birds indicates that the development of the system of osmotic concentration conditioned by the formation in the kidney of the medulla and from a sharp increase in renal arterial blood supply.
(15) There is no longer a sharp dividing line between working and rentiering.
(16) We are going to see a sharp fall unless sellers hold the sector up by making aggressive offers.
(17) A sharp increase in the intensity of lipids biochemiluminiscence and decrease in the tissue homogenates biochemiluminiscence were observed during the period of progressive tumour growth on the 6-8 days following introduction of the virus.
(18) By no means is this a new theme, but it has taken on an added sharpness and urgency after the conferences.
(19) The blood lymphocytes were small with scanty cytoplasm, densely condensed nuclear chromatin, and deep clefts originating in sharp angles from the nuclear surface.
(20) In sharp contrast, the coverage provided by the various mainstream news channels and newspapers not only seems – with some exceptions – unresponsive and stilted, but often non-existent.