(a.) Highest in rank, authority, character, importance, or degree; most considerable or important; chief; main; as, the principal officers of a Government; the principal men of a state; the principal productions of a country; the principal arguments in a case.
(a.) Of or pertaining to a prince; princely.
(n.) A leader, chief, or head; one who takes the lead; one who acts independently, or who has controlling authority or influence; as, the principal of a faction, a school, a firm, etc.; -- distinguished from a subordinate, abettor, auxiliary, or assistant.
(n.) The chief actor in a crime, or an abettor who is present at it, -- as distinguished from an accessory.
(n.) A chief obligor, promisor, or debtor, -- as distinguished from a surety.
(n.) One who employs another to act for him, -- as distinguished from an agent.
(n.) A thing of chief or prime importance; something fundamental or especially conspicuous.
(n.) A capital sum of money, placed out at interest, due as a debt or used as a fund; -- so called in distinction from interest or profit.
(n.) The construction which gives shape and strength to a roof, -- generally a truss of timber or iron, but there are roofs with stone principals. Also, loosely, the most important member of a piece of framing.
(n.) In English organs the chief open metallic stop, an octave above the open diapason. On the manual it is four feet long, on the pedal eight feet. In Germany this term corresponds to the English open diapason.
(n.) A heirloom; a mortuary.
(n.) The first two long feathers of a hawk's wing.
(n.) One of turrets or pinnacles of waxwork and tapers with which the posts and center of a funeral hearse were formerly crowned.
(n.) A principal or essential point or rule; a principle.
Example Sentences:
(1) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(2) While stereology is the principal technique, particularly in its application to the parenchyma, other compartments such as the airways and vasculature demand modifications or different methods altogether.
(3) Chromatography and immunoassays are the two principal techniques used in research and clinical laboratories for the measurement of drug concentrations in biological fluids.
(4) This paper reports, principally, the caries results of the first three surveys of 5, 12 and 5-year-olds undertaken at the end of 1987, 1988 and 1989, respectively.
(5) Rigidly fixing the pubic symphysis stiffened the model and resulted in principal stress patterns that did not reflect trabecular density or orientations as well as those of the deformable pubic symphysis model.
(6) The binding parameters indicate that the principal activating effect of UMP is not simply to increase the affinity of the enzyme for glucose.
(7) Mononuclear phagocytic cells from patients with either principal form of leprosy functioned similarly to normal monocytes in phagocytosis while their fungicidal activity for C. pseudotropicalis was statistically significantly altered and was more evident in the lepromatous than in the tuberculoid type.
(8) In the terminal segment of the hamster epididymidis there was some evidence of micro-merocrine protein secretion a the level of the principal cells and clear evidence of granular secretion in the light cells, presumable of glycoproteins.
(9) In the analysis of background fluorescence, the principal components were, as for the two-step technique, autofluorescence and propidium spectral overlap.
(10) However, at Period B, neutrophil numbers in the BAL fluid were increased in the principal but not in the control animals.
(11) Principal conclusions are: 1) rapid change to predominantly heterosexual HIV transmission can occur in North America, with serious societal impact; 2) gender-specific clinical features can lead to earlier diagnosis of HIV infection in women; 3) HIV infection in women does not pursue an inherently more rapid course than that observed in men.
(12) The concentrations of the principal extratesticular androgens and estradiol do not seem to have a quantitative influence on these androphilic proteins either.
(13) A principal function of GPIb is its attachment to von Willebrand Factor (vWF) on injured blood vessels which leads to the adhesion of platelets to these vessels.
(14) The principal variables influencing a particular configuration and their effects are indicated.
(15) The principal form of HMTs produced by these human peripheral blood monocytes has been subjected to biochemical, functional, and serological characterization.
(16) Micronutrient antioxidants such as alpha-tocopherol, the principal lipid-soluble antioxidant, assume potential significance because levels can be manipulated by dietary measures without resulting in side effects.
(17) Cytochrome oxidase histochemistry revealed patchy patterns of the enzyme activity in transverse sections through the caudal part of the ventral subnucleus of the principal sensory trigeminal nucleus, interpolar spinal trigeminal nucleus, and layer IV of the caudal spinal trigeminal nucleus in the cat.
(18) 3. an up-to-date review of the principal methods and systems used to measure the sedimentation rate--Automation of the Westergren initial methodology.
(19) • Queen Margaret Union, one of the University of Glasgow's two student unions, says 200 students there are marching on the principal's office at the moment to present an anti-cuts petition.
(20) This observation provides corroboration for the identification of the principal CCK-I neuron in the rat olfactory bulb as the centrally projecting middle tufted cell.
Protagonist
Definition:
(n.) One who takes the leading part in a drama; hence, one who takes lead in some great scene, enterprise, conflict, or the like.
Example Sentences:
(1) The Independent noted that one of the female protagonists yelled "You c***!"
(2) There are numerous other male protagonists out there in desperate need of a sex change.
(3) At times, they gained a momentum that took even the protagonists by surprise.
(4) Phase II is the attack and destruction of the allograft by these protagonists.
(5) Not relegate them to background characters in the service of a white cis-male fictional protagonist.” Both groups have drawn their conclusions from the film’s trailer.
(6) But the bedeviled foray also works as a potent allegory on the slow, vice-like workings of conscience, as guilt hunts down the protagonists with the shrieking remorselessness of Greek furies.
(7) We don’t need a man to help us or lead us … We’re protagonists who defend a Podemos for everyone.” Iglesias responded coolly, saying he was convinced there would be “far better candidates”.
(8) Owing to the poor quality of much of this research the claims of the protagonists of these therapies cannot be proved or disproved.
(9) The roles of each protagonist are related in detail, with pragmatism.
(10) In 90 engrossing minutes came comedy, controversy, drama, breathtaking moments and an eye-catching turn from the star protagonist himself.
(11) The novelist and critic Tom Bissell has described the protagonist's Jewish lawyer in 2002's Vice City as "an anti-Semitic parody of an anti-Semitic parody", while in the new game one of the main character's daughters has a tattoo that reads "skank", and one mission involves you helping a paparazzo capture a starlet's "low-hanging muff".
(12) "But where in Dostoevsky or Poe the protagonist experiences his double as a terrifying embodiment of his own otherness (and especially his own voraciousness and destructiveness), we barely notice the difference between ourselves and our online double.
(13) Despite the world-weary tone of a brutal review in the New York Times, which suggested that it added nothing new to the "groaning shelf" of homosexual literature, a story with an unashamedly gay protagonist unleashed a storm of protest in a country where sodomy was still illegal.
(14) It was probably all over for the idea of being stoned as a portal to a higher consciousness after the release of a film in which the two perma-baked protagonists drive a car with the numberplate MUF DVR.
(15) M∆tilda – spelt with an Alt-J – references Luc Besson's film Léon and is "fuelled by the shared demise of both the protagonist and antagonist".
(16) Protagonists of the method included Ambroise Paré, Thomas Fienus, Hieronymus Fabricius ab Aquapendente, Julius Casserius, and Johannes Scultetus.
(17) Facebook Twitter Pinterest Gone Girl star Ben Affleck: ‘Usually the protagonist is full of shit’ - video interview Fincher’s film narrowly beat another new film, the horror prequel Annabelle , into second place.
(18) But the protagonists – Patty especially – are constantly making new discoveries about themselves: redemptive insights, lessons in the contradictoriness of the human heart.
(19) Writing about her novel, Wolf Hall, Hilary Mantel has explained how she brought the protagonist Thomas Cromwell alive for the reader by giving him vivid memories.
(20) Another way of assessing the claim and counterclaim is to consider the characters of the protagonists.