What's the difference between prolonged and wretchedness?

Prolonged


Definition:

  • (imp. & p. p.) of Prolong

Example Sentences:

  • (1) Without medication atypical ventricular tachycardia develops, in the author's opinion, most probably when bradycardia has persisted for a prolonged period.
  • (2) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
  • (3) In Patient 2 they were at first paroxysmal and unformed, with more prolonged metamorphopsia; later there appeared to be palinoptic formed images, possibly postictal in nature.
  • (4) Morphological alterations in the lungs of pheasants after prolonged high-dosage administration of bleomycin sulfate were studied by light and electron microscopy.
  • (5) Graft life is even more prolonged with patch angioplasty at venous outflow stenoses or by adding a new segment of PTFE to bypass areas of venous stenosis.
  • (6) We evaluated the circadian pattern of gastric acidity by prolonged intraluminal pHmetry in 15 "responder" and 10 "nonresponder" duodenal ulcer patients after nocturnal administration of placebo, ranitidine, and famotidine.
  • (7) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
  • (8) Prolonged immobilization was accompanied by a decrease in Ca-concentration dependence of Ca2+ uptake.
  • (9) Defibrotide prevents the dramatic fall of creatine phosphokinase activity in the ischemic ventricle: metabolic changes which reflect changes in the cells affected by prolonged ischemia.
  • (10) With prolonged ischemia, it is only transient and is followed by a gradual loss of the adenylyl cyclase activity.
  • (11) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
  • (12) The mechanism by which gp55 causes increased erythroblastosis and ultimately leukaemia is unknown, but a reasonable suggestion is that gp55 can mimic the action of erythropoietin by binding to its receptor (Epo-R), thereby triggering prolonged proliferation of erythroid cells.
  • (13) This condition may be caused by the prolonged, repetitive elevations of gonadal steroids and other hormones known to suppress gonadotropin-releasing hormone secretion that are elicited by their daily exercise.
  • (14) There was no correlation between disturbed gastric clearance, impaired gall bladder contraction, and prolonged colonic transit time in the patients with cardiovascular autonomic neuropathy nor was there a correlation between any disturbed motor function and age or duration of diabetes.
  • (15) Attempts were made to prolong the survival of the grafts by the use of cytotosine arabinoside, methylprednisolone, heparin and azathioprine.
  • (16) Because of these different direct and indirect actions, a sudden cessation of sinus node activity or sudden AV block may result in the diseased heart in a prolonged and even fatal cardiac standstill, especially if the tolerance to ischemia of other organs (notably the brain) is decreased.
  • (17) The 14-fold increase in prolonged apnea frequency immediately following regurgitation supports the hypothesis for a causal relationship between apnea and regurgitation.
  • (18) Chromatolysis and swelling of the cell bodies of cut axons are more prolonged than after optic nerve section and resolve in more central regions of retina first.
  • (19) Cryopreserved autologous blood cells may thus restore some patients with CGL in transformation to chronic-phase disease and so may help to prolong life.
  • (20) Heparin prolonged by 15 s and 45 s the time required to demonstrate Factor V activation in CAP supplemented with Factor Xa and thrombin respectively.

Wretchedness


Definition:

  • (n.) The quality or state of being wretched; utter misery.
  • (n.) A wretched object; anything despicably.

Example Sentences:

  • (1) Alexis Tsipras, the former student radical who leads the party, has called the latest €130bn rescue plan "barbaric" and "an agreement of poverty and wretchedness".
  • (2) Obviously Pantilimon is more abject than Hart,” says Graham Lees “and Demichelis must have lied on his CV but why does no one bemoan the wretchedness, sorry, opportunity gifted to Sunderland, of Nasri’s selection?
  • (3) The clinic's wheelchairs have white plastic seats cut from garden furniture, lending an incongruous jauntiness to the wretchedness.
  • (4) From this wretchedness, Labour emerged to give people basic rights and a sense of dignity in work.
  • (5) "I don't believe in heroes or saviours," says Alexis Tsipras, "but I do believe in fighting for rights … no one has the right to reduce a proud people to such a state of wretchedness and indignity."
  • (6) His is not the first image to have encapsulated the wretchedness of the Syrian war.
  • (7) They are falling fast towards the relegation zone while teams below are sprouting wings, none more so than Leicester, whose late-season surge continued here thanks to two goals from Leonardo Ulloa, one by Wes Morgan, and the wretchedness of a Newcastle side that finished with nine men and were accused of cowardice by their own manager.
  • (8) The current government has taken it to an entirely new level of wretchedness in its determination to “stop the boats”.
  • (9) From early, delicate watercolours to his cycles of despoiled paintings, this retrospective gives full measure to Kiefer’s preoccupations with German history, the holocaust, mythology and the wretchedness of our age.
  • (10) Both crime and the taking of illicit drugs are reflections of the divisions, hatreds and wretchedness that have long existed within our society and within the individuals that comprise it.
  • (11) Young, still managing to stand out for his wretchedness, was guilty late on of losing the ball in the build-up to City's fourth goal and Moyes, finally, had seen enough, substituting him straight away.