(a.) Kicking back; recalcitrating; hence, showing repugnance or opposition; refractory.
Example Sentences:
(1) Based on the principles of adaptational mutations and genetic exchange of catabolic activities, it becomes possible to select and engineer microorganisms that are suitable for the degradation of recalcitrant compounds.
(2) A prospective, randomized, double-blind, placebo-controlled multicentre study assessed the clinical efficacy and safety of pulsed electromagnetic limb ulcer therapy (PELUT) in the healing of recalcitrant, predominantly venous leg ulcers.
(3) We present a patient whose genital warts were recalcitrant to treatment.
(4) Isotretinoin (Accutane Capsules) is a synthetic vitamin A compound used for treatment of recalcitrant cystic acne.
(5) Such gene cassettes or operons can be transferred into suitable microbial hosts for extending and custom designing the pathways for rapid degradation of recalcitrant compounds.
(6) Of the 30 patients with warts, most of which were recalcitrant, 14 were cured and the remaining 16 showed marked improvement.
(7) This procedure is a simple and effective method for safe office treatment of patients with recalcitrant recurrent erosion.
(8) The thermal cycle sequencing procedures are advantageous because they allow fast and simple semiautomation of the sequencing reaction; make possible the direct DNA sequencing of PCR products, bacterial colonies and phage plaques; require only femtomoles of template DNA; eliminate the requirement of an independent primer annealing step; remove the requirement of denatured plasmids for sequencing double-stranded templates; and use a highly thermostable DNA polymerase for sequencing through potential recalcitrant secondary structure domains and large linear double-stranded DNA templates such as lambda derivatives.
(9) To study the human teratogenicity of this agent, we investigated 154 human pregnancies with fetal exposure to isotretinoin, a retinoid prescribed for severe recalcitrant cystic acne.
(10) The biosynthesis of prostaglandins (PG) in biopsies from 9 patients with recalcitrant psoriasis was studied before, during, and after treatment with 8-methoxy-psoralen and long-wave ultraviolet light (UVA).
(11) The Dec+ mutants had also acquired the capacity to metabolize other recalcitrant branched hydrocarbons such as 3,6-dimethyloctane and 2,6-dimethyldecane.
(12) Levamisole should be tried in recalcitrant chronic candidoses and bacterial infections not responding to specific antibiotic treatment.
(13) Thus, combination therapy is recommended for treatment of recalcitrant cases of bacterial endocarditis caused by N. mucosa.
(14) If the holding phase is sufficiently prolonged, a reduction in the number and complexity of operative procedures needed for recurrent and recalcitrant cases can be expected.
(15) Treatment of associated systemic disorders may improve the ulcers, but lesions may be recalcitrant and persist for months to years.
(16) Cyclosporine, an immunosuppressive drug, is effective in the treatment of recalcitrant psoriasis.
(17) In recalcitrant cases, however, entrapment of the first branch lateral plantar nerve should be suspected.
(18) These autonomous movements were otherwise recalcitrant to therapy and were felt to arise from neural generators intrinsic to the spinal cord.
(19) The effectiveness and tolerance of isotretinoin have been assessed in 72 cases (34 male and 38 female) suffering from papulo-pustular acne with nodulo-cystic component recalcitrant to traditional treatments.
(20) The government’s strategy is clearly based on a deep confidence that it has time, that it won’t be forced back to the polls by a recalcitrant Senate, that it will have years to reach a rapprochement with the angry states and that it will bring down two more budgets before it has to face the voters.
Refractory
Definition:
(a.) Obstinate in disobedience; contumacious; stubborn; unmanageable; as, a refractory child; a refractory beast.
(a.) Resisting ordinary treatment; difficult of fusion, reduction, or the like; -- said especially of metals and the like, which do not readily yield to heat, or to the hammer; as, a refractory ore.
(n.) A refractory person.
(n.) Refractoriness.
(n.) OPottery) A piece of ware covered with a vaporable flux and placed in a kiln, to communicate a glaze to the other articles.
Example Sentences:
(1) During electrophysiologic study, the effect of propafenone on the effective refractory period of the accessory pathway was determined, as well as its effect during orthodromic atrioventricular (AV) reentrant tachycardia and atrial fibrillation.
(2) Some evidence has shown that platelet crossmatching is useful in multitransfused patients with hypoplastic bone marrows who are refractory to platelet therapy through alloimmunization.
(3) The purpose of this study was to determine the effect of pretreatment with indomethacin on the refractory period to hypertonic saline-induced bronchoconstriction.
(4) This quantitative characterization of the properties of conduction and refractoriness of both the accessory pathway and ventriculoatrial conduction system and the relation between these characteristics and the accessory pathway location in ART patients provides additional insight into the prerequisites for the initiation and maintenance of this rhythm disturbance.
(5) Lisinopril increases cardiac output, and decreases pulmonary capillary wedge pressure and mean arterial pressure in patients with congestive heart failure refractory to conventional treatment with digitalis and diuretics.
(6) Extracorporeal photopheresis (ExP) was administered every other week in an outpatient setting to four patients with chronic refractory psoriasis vulgaris without arthropathy.
(7) Populations of B. globosus and B. nasutus from Dar es Salaam were refractory.
(8) When caffeine evokes a contraction, and only then, crayfish muscle fibers become refractory to a second challenge with caffeine for up to 20 min in the standard saline (5 mM K(o)).
(9) We present in this preliminary report the early results of therapy for refractory leukemia with an intensive preparative regimen for bone marrow transplantation including etoposide, cytosine arabinoside, cyclophosphamide, and fractionated total body irradiation.
(10) Amiodarone was able to suppress the premature ventricular beats, depress conduction and prolong refractoriness in both, the AV node and accessory pathway to prevent recurrences of atrioventricular reentry.
(11) Once initiated, this refractory state continues to develop even after removal of the light source and is essentially complete within 30 min.
(12) At lower frequencies of stimulation the heart beat is increased to rates dependent on interaction between the time course of the hyperpolarization and the refractory period of the heart.
(13) The results indicate that the conditions which inhibit the initiation of development are present in the Malpighian tubules and not in the midgut of the refractory mosquitoes.
(14) Parenteral cyclophosphamide or corticosteroid pulses should be reserved for cases with vasculitis or refractoriness to conventional drugs.
(15) These data suggest that in terms of prolactin release, prolactin producing tumour cells are intrinsically refractory to hypo thalamic dopaminergic signals.
(16) Pirmenol increased the atrial effective refractory period, but had little effect on conduction in the atrioventricular node and His-Purkinje system.
(17) Estramustine phosphate may be given safely for a prolonged period and has a place in the treatment of advanced prostatic cancer refractory to hormonal therapy.
(18) One or more of the followin factors were present in the "high-risk" group: ventricular dysfunction--ejection fraction less than 0.4, preinfarction angina, evolving infarction, recent infarction (less than 2 weeks), and refractory ventricular tachyarrhythmia.
(19) Although video urodynamics is the state-of-the-art modality for evaluating complex or refractory neurogenic bladder, the practicing radiologist with an understanding of this condition can detect many radiographic changes in the lower urinary tract that suggest neurogenic dysfunction of various types.
(20) Tinidazole (not available in the United States) may be effective in curing refractory cases of metronidazole resistance.