(1) There was appreciable variation in toothbrush wear among subjects, some reducing their brush to a poor state in 2 weeks whereas with others the brush was rated as "good" after 10 weeks.
(2) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(3) These included bringing in the A* grade, reducing the number of modules from six to four, and a greater attempt to assess the whole course at the end.
(4) It is concluded that amlodipine reduces myocardial ischemic injury by mechanism(s) that may involve a reduction in myocardial oxygen demand as well as by positively influencing transmembrane Ca2+ fluxes during ischemia and reperfusion.
(5) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(6) With aging, the blood vessel wall becomes hyperreactive--presumably because of an augmented vasoconstrictor and a reduced vasodilator responsiveness.
(7) In addition, DDT blocked succinate dehydrogenase and the cytochrome b-c span of the electron transport chain, which also secondarily reduced ATP synthesis.
(8) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(9) At pH 7.0, reduction is complete after 6 to 10 h. These results together with an earlier study concerning the positions of the two most readily reduced bonds (Cornell J.S., and Pierce, J.G.
(10) Methanosphaera stadtmanae reduces methanol to CH4 in a similar way as Methanosarcina barkeri.
(11) There is no evidence that health-maintenance organizations reduce admissions in discretionary or "unnecessary" categories; instead, the data suggest lower admission rates across the board.
(12) In schizophrenic patients the density of dopamine uptake sites in the basal ganglia was slightly reduced, mainly in the middle third of putamen.
(13) During recovery glucose uptake was reduced and citrate release was unaffected.
(14) The difference in BP between a hospital casual reading and the mean 24 hour ambulatory reading was reduced only by atenolol.
(15) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(16) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(17) aeruginosa and Enterococci) were significantly reduced in number during the manipulation (Fig.
(18) Arginine vasopressin further reduced papillary flow in kidneys perfused with high viscosity artificial plasma.
(19) Epidermal growth factor reduced plating efficiency by about 50% for A431 cells in different cell cycle phases whereas a slight increase in plating efficiency was seen for SiHa cells.
(20) Nicardipine lowered systolic and diastolic blood pressure to normal, plasma aldosterone was reduced and serum potassium levels were increased.
Unmitigated
Definition:
Example Sentences:
(1) The last time policymakers resorted to such draconian measures was an unmitigated disaster: following the SEC's ban on naked short-selling of financial shares in late 2008, the S&P 500 index lost 21.5% of its value during the period of the veto.
(2) We share a responsibility to our future patients to address unmitigated climate change – described as “the biggest health threat of the 21st century” – and to advocate for a transition to a healthier, more sustainable economy.
(3) Myth 6: biofuels are always destructive to the environment Making some of our motor fuel from food has been an almost unmitigated disaster.
(4) They’re not going to be announcing, like they did at Carrier, that they’re closing up and they’re moving to Mexico.” So an unmitigated triumph for Trump?
(5) The Republican chairman of the House armed services committee, Californian Buck McKeon, castigated it as an unmitigated disaster.
(6) When he strokes the blank sheets the narrator notes his happiness: "Not for years, not since 1914 , had I witnessed an expression of such unmitigated happiness on the face of a German .
(7) The transfer window is currently six days old and so far it's been nothing short of an unmitigated, egregious waste of time.
(8) The chronic production of lipid peroxide-modified Lp(a) together with unmitigated cellular clearance by scavenger receptors may contribute to the accumulation of lipoprotein-derived lipid in macrophage-derived foam cells of the atherosclerotic reaction.
(9) The venture was a "flat, rank and unmitigated failure", wailed the man who had more or less invented popular journalism by creating the Daily Mail.
(10) "I don't see how anyone could invest in this company any longer," ISI Group analyst Brian Marshall told Associated Press, describing it as "an unmitigated train wreck".
(11) Ukip remains the great unknown Nigel Farage's Ukip conference was an unmitigated disaster.
(12) The display of cabinet solidity may not be all it seems: many know full well that their leader is an almost unmitigated electoral liability.
(13) On the first day back after the Christmas break, all that David Cameron could remember of December’s European Union summit was that it had been an unmitigated triumph.
(14) All that may happen is that prices of established dwellings go up less quickly than they would otherwise – and I think that would be an unmitigated good thing.” So now a line of economists, think-tanks, community groups and even Tony Abbott’s chair of the audit commission, Tony Shepherd, are on the record as calling for change to negative gearing and capital gains tax concessions.
(15) Phil Dorrell, director of retail consultants Retail Remedy From day one, Fresh & Easy was an unmitigated disaster for Tesco.
(16) Decision theory's role in medicine will lie between the extremes of naive optimism ("a Rosetta stone") and unmitigated pessimism ("a computerized Ouija board").
(17) The Case Against 8 – a documentary about the fight to overturn California's voter referendum that prohibited same-sex marriage for five years – leaves viewers with the unmitigated impression that Proposition 8 was overturned by a small group of very rich white people, the Great White Hope of Marriage Equality.
(18) 'Real fight starts now': Jeremy Corbyn's Brexit tweet prompts bruising response Read more Perhaps Brexit will be an unmitigated disaster – but even if it is, will the public blame the government and turn to the politicians who sought to block it in the first place?
(19) For the only western democracy without a human rights act or a developed constitutional underpinning of human rights, putting up our hand for a seat at the table looks like a piece of unmitigated presumption.
(20) This is the moment, in a life story of unmitigated misfortune, when you might expect that things would begin to improve.