(1) Injection of 0.001 Goldblatt u. renin into the angiotensin-sensitive region causes the water-replete rat to drink.
(2) The duodenal mucosa of genotypically normal iron replete and iron deficient mice and mice with sex-linked (sla) and microcytic anemias (mk) was examined for the presence of iron-binding proteins.
(3) Accordingly, we repleted vitamin D-depleted rats with subcutaneous injections of 2600, 520, and 130 pmoles of cholecalciferol (D3), 25-hydroxycholecalciferol (25(OH)D3), and 1,25-dihydroxycholecalciferol (1,25(OH)2D3), respectively, for up to 3 weeks.
(4) Since this protein is present in growing teeth, we have examined its synthesis in teeth from vitamin D-replete and -deplete rats by Western blotting and immunocytochemistry with an antiserum to CaBP 28 K purified from rat kidney.
(5) It was found to remain intact until at least 11, 30 and 10 days after repletion in larvae, nymphs and females, respectively.
(6) Gastroduodenal investigation must of course be comprised of pictures during collapse, semi-collapse and repletion of the entire duodenal outline; once out of every two times, one has to recourse to intravenous duodenography which has become a routine investigation.
(7) The responses to Ca depletion and repletion, Na depletion and repletion, and 1 microM ryanodine indicate that the contribution of Ca to contraction from the slow pool is much greater in the rat than in the rabbit and that its cellular locus is probably the sarcoplasmic reticulum.
(8) Uptake (30 min in Na(+)-free buffer) of histidine, kynurenine, leucine, tyrosine, and a model substrate for System L transport was 70-150% greater in Gln-replete cultures.
(9) Vitamin A repletion significantly reverses retinal degeneration from the Z-A- state even in the presence of moderate zinc deficiency.
(10) The same measurements were also made in two of the dogs during potassium repletion.
(11) Because of the variable responses of plasma ferritin concentration to iron depletion and repletion and the lack of relationship between plasma and liver ferritin concentrations, it is concluded that plasma ferritin concentration is not a good indicator of iron status in rats.
(12) These increased activities were reduced to those of folate-replete cells by co-culture of folate-deficient cells with thymidine.
(13) Nutritional repletion also significantly increased serum C(3), C(4) and C(3)PA concentrations.
(14) His home, an hour from Athens, is a mansion replete with large statues, candelabras, paintings on every wall in every room and many images of Jesus.
(15) Ca2+ repletion following Ca2+-free superfusion resulted in a rapid but small increase in resting tension that was not followed by contracture, nor was it associated with a significant increase in [3H]IPs accumulations.
(16) Although no changes could be detected in the conventional B lymphocyte population, the peritoneum was replete with B cells characteristic of the Ly-1 lineage.
(17) To examine whether the concentration gradient of glutamine (Gln) drives concentrative Na(+)-independent uptake of neutral amino acids (NAA) in mouse cerebral astrocytes, uptake was compared in "Gln-depleted" and "Gln-replete" cultures.
(18) We have been able to quantitate both of these parameters under a variety of experimental conditions using a unique essential fatty acid-deficient mouse fibrosarcoma cell line (EFD-1), which when repleted with arachidonate, produces prostaglandin E2 (PGE2).
(19) At exhaustion in these hearts %I increased significantly in response to a decrease in G. These findings suggest that glycogen repletion occurs in normal heart as a result of the combined increases in GS %I and G-6-P levels present at the cessation of work.
(20) The effects were reversed after 8 weeks of repletion.
Steep
Definition:
(a.) Bright; glittering; fiery.
(v. t.) To soak in a liquid; to macerate; to extract the essence of by soaking; as, to soften seed by steeping it in water. Often used figuratively.
(v. i.) To undergo the process of soaking in a liquid; as, the tea is steeping.
(n.) Something steeped, or used in steeping; a fertilizing liquid to hasten the germination of seeds.
(n.) A rennet bag.
(v. t.) Making a large angle with the plane of the horizon; ascending or descending rapidly with respect to a horizontal line or a level; precipitous; as, a steep hill or mountain; a steep roof; a steep ascent; a steep declivity; a steep barometric gradient.
(v. t.) Difficult of access; not easy reached; lofty; elevated; high.
(v. t.) Excessive; as, a steep price.
(n.) A precipitous place, hill, mountain, rock, or ascent; any elevated object sloping with a large angle to the plane of the horizon; a precipice.
Example Sentences:
(1) The dose response effect in this tumor is steep and combinations which compromise the dose of adriamycin too greatly are showing inferior results.
(2) Steep longitudinal and transverse gradients of glycogen are known to exist in the organ of Corti of the guinea pig, with preferential accumulation in the outer hair cells of the apical turns.
(3) The steep portion of the relationship between Retzius cell action potential amplitude and membrane potential extrapolated to an apparent reversal potential of -13 mV.
(4) This property of endotoxin can serve as a sensitive bioassay, although the dose-response curve is steep.
(5) With its steep hills and cobblestones, the neighbourhood of São Cristóvão in Ouro Preto isn’t an easy place to play football.
(6) Four patients with herpes zoster ophthalmicus developed peripheral corneal ulcers with steep central edges.
(7) The results showed that measurements of impression profiles and SEM photogrammetry gave the most accurate results adjacent to regions simulating steep cavity margins, whereas the profilometric technique gave erroneous results in these regions.
(8) The intensity dependence of the early ganglion cell discharge, its latency and initial impulse frequency, is shown to follow from such a waveform, assuming that 1) latency L = l + D, where l is the time it takes for the rod response linearly summed over the ganglion cell's receptive field to reach a criterion amplitude, and D is a constant delay; and 2) the initial frequency (below saturation) is proportional to the steepness of rise of the summed rod response at time l. It is shown that the intensity dependences of 1) human visual latency and 2) brightness sensation, including effects of stimulus area and duration, are accounted for by the same model.
(9) The new protocol (standardised exponential exercise protocol, STEEP) is suitable for use on either a treadmill or a bicycle ergometer.
(10) Based on the signals observed by organ absorbance spectrophotometry from two compartments with oxidases of markedly different O2 sensitivity, the mitochondria and the peroxisomes, a distribution between high O2 and zero O2 zones is postulated, an intermediate border zone of O2 concentrations between the K0,5 (O2) values being virtually absent (steep intercellular O2 gradients).
(11) A man who had been near them reached the hotel terrace first, scrambling up a steep sandy bank.
(12) Patients with steep sloping audiograms understand better and patients with a conductive hearing loss component understand less in noisy circumstances with a hearing aid.
(13) The operational values are useful in characterising the steepness of dose-incidence curves for normal tissue injury after different fractionation schedules.
(14) Scarborough council said leaving the houses standing could cause a domino-effect down the steep slope above the picturesque harbour where the explorer Captain James Cook lodged and learned his seafaring skills.
(15) It is shown that this individual exhibits approximate alignment of her photoreceptors with the center of the retinal sphere, clear evidence of side lobes on functions, and surprisingly steep SCE I functions.
(16) For cross-linked alpha alpha, however, the curve sags at temperatures somewhat below the region of principal cooperative loss of helix, the latter occurring at higher temperature but with the same steepness as in the non-cross-linked case.
(17) A reduced venous compliance (VC) and inadequate venoconstriction may impair hemodynamics during hemodialysis, the first by impairing plasma volume preservation and by inducing a steep fall in central venous pressure (CVP) during minor plasma volume loss, the second by inadequate mobilization of hemodynamically inactive blood volume.
(18) A generally similar pattern is seen in healthy controls and in patients with untreated pulmonary tuberculosis, treated leprosy, haemophilia A and chronic obstructive lung disease (COLD) patients treated with prednisolone, but the gradient of increasing CD4:CD8 ratio with depth into the dermis is significantly less steep in patients with tuberculosis, haemophilia and prednisolone-treated COLD than in the healthy controls.
(19) Some problem drugs may be recognized if they display one or more of the following characteristics: narrow therapeutic index, steep dose-effect relationship, nonlinear kinetics, variable bioavailability, and pharmacogenetically determined kinetics.
(20) Replacement of a half of Ca++ ions by Sr++ resulted in an augmentation of steepness of the dependence on sum of [Ca++] and [Sp++], and in a more prominent fall in relaxation velocity as compared with contraction velocity.