(n.) Having inequalities, small ridges, or points, on the surface; not smooth or plain; as, a rough board; a rough stone; rough cloth.
(n.) Not level; having a broken surface; uneven; -- said of a piece of land, or of a road.
(n.) Not polished; uncut; -- said of a gem; as, a rough diamond.
(n.) Tossed in waves; boisterous; high; -- said of a sea or other piece of water.
(n.) Marked by coarseness; shaggy; ragged; disordered; -- said of dress, appearance, or the like; as, a rough coat.
(n.) Hence, figuratively, lacking refinement, gentleness, or polish.
(n.) Not courteous or kind; harsh; rude; uncivil; as, a rough temper.
(n.) Marked by severity or violence; harsh; hard; as, rough measures or actions.
(n.) Loud and hoarse; offensive to the ear; harsh; grating; -- said of sound, voice, and the like; as, a rough tone; rough numbers.
(n.) Austere; harsh to the taste; as, rough wine.
(n.) Tempestuous; boisterous; stormy; as, rough weather; a rough day.
(n.) Hastily or carelessly done; wanting finish; incomplete; as, a rough estimate; a rough draught.
(n.) Produced offhand.
(n.) Boisterous weather.
(n.) A rude fellow; a coarse bully; a rowdy.
(adv.) In a rough manner; rudely; roughly.
(v. t.) To render rough; to roughen.
(v. t.) To break in, as a horse, especially for military purposes.
(v. t.) To cut or make in a hasty, rough manner; -- with out; as, to rough out a carving, a sketch.
Example Sentences:
(1) By 24 hr, rough endoplasmic reticulum in thecal cells increased from 4.2 to 7% of cell volume, while the amount in granulosa cells increased from less than 3.5% to more than 10%; the quantity remained relatively constant in the theca but declined to prestimulation values in the granulosa layer.
(2) Thus, it appears that neuronal loss may account for up to roughly half of the striatal D2 receptor loss during aging.
(3) The cis isomer was retained longer in liver, particularly in mitochondria, but had low retention in that portion of the endoplasmic reticulum isolated as the rough membrane fraction.
(4) The results indicated that roughly 25% of patients treated in this way will become hypothyroid after 5 years and that 85% are cured (need no further therapy during the follow-up period) using a single dose of iodine-131.
(5) This heretogeneity occurred mainly as a progressive, decreasing gradient in the first half of this pathway, between the rough endoplasmic reticulum and the mi-cisternae of the Golgi apparatus.
(6) Electron microscopy revealed a well-developed rough endoplasmic reticulum, an enlarged Golgi apparatus and many highly electron-dense secretory granules resembling those of Clara cells.
(7) Four fractions enriched, respectively, in plasma membrane (PM), smooth endoplasmic reticulum (SER), rough endoplasmic reticulum (RER), and mitochondria were isolated from estrogen-dominated rat myometrium.
(8) For trials in which the target was present in the array, RT functions were roughly symmetric, the shortest RTs being for extreme distractor ratios, and the longest RTs being for arrays in which there were an equal number of each distractor type.
(9) Classic technics of digital image analysis and new algorithms were used to improve the contrast on the full image or a portion of it, contrast a skin lesion with statistical information deduced from another lesion, evaluate the shape of the lesion, the roughness of the surface, and the transition region from the lesion to the normal skin, and analyze a lesion from the chromatic point of view.
(10) Electron microscopic evaluation of microsomal fractions showed elements of the plasma membrane, including cilia and microvilli, as well as rough and smooth endoplasmic reticulum.
(11) The local guide led us down a rough, uneven pathway, talking as he went.
(12) It's the roughly $2bn in revenue grossed by his blockbuster movies, some of which he had to be talked into making.
(13) The interaction between PE and E-IgG involved the extension of micropseudopods toward adherent E-IgG, the formation of a linear uniform cap of roughly 200 A between opposing cell membranes, the ingestion of E-IgG by PE into a membrane-lined compartment, and the disintegration of the ingested ligand into membranous debris.
(14) Ultracentrifugally separated HDL2 and HDL3 roughly corresponded to HDL2e and HDL3e, respectively.
(15) The locations of these 15 insertion sites correlate well with the roughly estimated locations of five of the DNase I-hypersensitive subregions.
(16) The Lords will vote on three key amendments: • To exclude child benefit from the cap calculation (this would roughly halve the number of households affected).
(17) The unique structure we describe is a cytoplasmic organelle which, like annulate lamellae, is closely associated with the endoplasmic reticulum and is presumed to be related to the genesis of rough-surfaced endoplasmic reticulum in tumor cells.
(18) Besides the rough, wrinkled, and brown or black surface of the fingertips, microwrinkles of the epidermis occur on the skin ridges, which have so far not been described.
(19) Ultrastructural examination of noncartilaginous regions of the tumor demonstrated mesenchymal cells with features suggestive of cartilaginous differentiation, viz, scalloped cell membranes, sac-like distension of abundant rough endoplasmic reticulum, and a matrix containing fibrillary and finely granular material.
(20) That, roughly, was the theme of the Wednesday Play, Cathy Come Home, (BBC1) directed by Kenneth Loach, produced by Tony Garnett.
Unbreakable
Definition:
Example Sentences:
(1) Nina Funnell’s terrifying physical assault detailed in Unbreakable is something her mind endures out-of-time, “valiantly trying to protect me from the trauma of what was occurring”.
(2) Fitness for purpose should not accompany Westminster’s repair – it should be its unbreakable requirement.
(3) Until then, we have an unbreakable moral obligation to save them.
(4) We have an unbreakable option with both Lanzini and his club, so any other team’s interest is irrelevant.
(5) While a little less than 60% of protective eye glasses were equipped with unbreakable lenses, 40% of protective glasses were simple eye guards, containing no lens at all.
(6) At least that’s the implication from FBI director Jim Comey’s push to ban unbreakable encryption and deliberately weaken everyone’s security.
(7) He added: “As Americans, we are in his debt because, having worked with every US president since John F Kennedy, no one did more over so many years as Shimon Peres to build the alliance between our two countries – an unbreakable alliance that today is closer and stronger than it has ever been.” The UN secretary general, Ban Ki-moon, said: “He worked tirelessly for a two-state solution that would enable Israel to live securely and harmoniously with the Palestinians and the wider region.
(8) A series that followed the mixed fortunes of a group of guys whose unbreakable bond transcended their turbulent personal and professional relationships.
(9) Donald Trump has made a gushing show of friendship to the French leader, Emmanuel Macron, saying the two countries had an “unbreakable bond” , pledging to draw up a road map for post-conflict Syria, and asserting that the two leaders could work together despite clear differences on climate change.
(10) A filibuster, which would be unbreakable unless the Democratic leadership can muster 60 votes, would allow wavering politicians to avoid having to reveal where they stand in the fraught gun debate.
(11) In April, the star announced that she was delaying her Unbreakable tour because she and her husband, businessman Wissam Al Mana, were “planning our family”.
(12) Forget Edmund Burke 's grand myth of British history's unbreakable continuity – as an Irishman he should have known better: constitutional ruptures in these islands come round with the regularity of comets, pretty much every century.
(13) Treaties can be broken but our partnership is unbreakable.
(14) The prosthesis is non-reactive, virtually unbreakable, and undentable.
(15) According to Channel 4, Farnaby will be seeking out "magnetic boys" in Croatia, Serbia's "human battery", and an "unbreakable monk" in China.
(16) The H gene theory, postulates that the main defense against autoimmune disease is mediated by the permanent, unbreakable tolerances imposed on the clonal repertoire by the histocompatibility (H) antigens, major, minor and H-Y.
(17) However, a 7z archive with a password of, say, 40 characters is probably unbreakable in the foreseeable future.
(18) Made of clear polystyrene, with adjustable pegs of the same material, the device is small, light, unbreakable and easily portable.
(19) Vicious circles of economic instability, devaluation, and capital flight have brought down seemingly unbreakable regimes throughout history.
(20) Specimens plastinated with an epoxy-silicone copolymer are rigid enough to be polished, but are not unbreakable.