(a.) Undisturbed by passion or caprice; calm; tranquil; serene; not passionate or giddy; composed; staid; as, a sedate soul, mind, or temper.
Example Sentences:
(1) The effects of sessions, individual characteristics, group behavior, sedative medications, and pharmacological anticipation, on simple visual and auditory reaction time were evaluated with a randomized block design.
(2) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(3) However, the degree of sedation caused by diphenhydramine was significantly greater than that caused by cimetidine (P = .0001).
(4) Although lorazepam and haloperidol produced an equivalent mean decrease in aggression, significantly more subjects who received lorazepam had a greater decrease in aggression ratings than haloperidol recipients; this effect was independent of sedation.
(5) Adverse outcomes were reported more frequently by consultant physicians, by those who 'titrated' the intravenous sedative, and by those who used an additional intravenous agent, but were reported equally frequently by endoscopists using midazolam and endoscopists using diazepam.
(6) Alterations in mean systolic blood pressure appeared to be modest, consisting of a 10 percent decrease from the control level, related to sedation, and a 10 percent rise from baseline during the procedure, associated with a concomitant mild tachycardia.
(7) We have evaluated the action of hypnotics on the sleep-wakefulness cycle in freely implanted rats during their maximally active period because it is easier to estimate the duration of the sedative effect.
(8) A survey into the current usage of tracheal tubes and associated procedures, such as various sedation regimes and antacid therapy, in intensive care units was carried out in Sweden by sending a questionnaire to physicians in charge of intensive care units in 70 acute hospitals which included seven main teaching hospitals.
(9) The results show that both drugs possess sedative, antispasmodic, antipyretic, antiinflammatory, cardiotonic and hypotensive effects, the strength of effect and toxicity being similar.
(10) This suggests that the fluphenazine-induced sedation is not mediated via its effect on brain NA content, but is possibly due to the effect of the drug on NA turnover rates in the brain.
(11) The introduction of non-sedating H1-selective antihistamine drugs and local corticosteroids has been an important therapeutic advance.
(12) Neither a sedative nor other side effects could be seen.
(13) Sedation was measured by asking the subjects to complete visual analog scales.
(14) Smoking behaviour, self-reported mood and cardiac activity were examined in 12 "sedative" and 12 "stimulant" smokers, defined using Mangan and Golding's questionnaire.
(15) Patients in the reference group used more sedatives and long-acting nitroglycerine and had a lower return-to-work rate during the study period.
(16) A prospective study of the necessity of sedation, or analgesia, or both in total colonoscopy was performed.
(17) Fifteen consecutive patients on peritoneal dialysis who complained of chronic sleep disturbance and requested sedative were selected.
(18) Sedative interaction between midazolam and morphine was found to have a tendency for synergism (interaction coefficient of 1.56, P greater than 0.05) with decreased individual variability in the sedative response to the combination.
(19) Both drugs were relatively well tolerated, but trimipramine had a sedative effect which proved troublesome in some patients.
(20) None of the patients required anaesthesia, analgesics or sedatives.
Sober
Definition:
(superl.) Temperate in the use of spirituous liquors; habitually temperate; as, a sober man.
(superl.) Not intoxicated or excited by spirituous liquors; as, the sot may at times be sober.
(superl.) Not mad or insane; not wild, visionary, or heated with passion; exercising cool, dispassionate reason; self-controlled; self-possessed.
(superl.) Not proceeding from, or attended with, passion; calm; as, sober judgment; a man in his sober senses.
(superl.) Serious or subdued in demeanor, habit, appearance, or color; solemn; grave; sedate.
(v. t.) To make sober.
(v. i.) To become sober; -- often with down.
Example Sentences:
(1) It's typically sober and elegant, and Cotillard excels in a nervy, vulnerable role.
(2) Read Rachel’s full story Facebook Twitter Pinterest Chris Owen: ‘I’ve been sober for six years now, and I don’t miss alcohol.’ Photograph: Graeme Robertson for the Guardian I spent my 20s playing Russian roulette with alcohol The NHS has been there time and time again for Chris Owen, who battled alcoholism throughout his 20s.
(3) Anthony Wells, director of YouGov’s political and social research team, said: “While there will be speculation about whether this movement is connected to the tragic death of Jo Cox, we do not think that it is... We are now in the final week of the referendum campaign and the swing back towards the status quo appears to be in full force.” EU referendum voters unconvinced by scare tactics: ‘I just want to do what’s right’ Read more Today, both sides will resume their battle to capture the votes of the undecided and to persuade people to switch sides, though both the Leave and Remain camps say that the manner of their campaigning will be more sober and less combative.
(4) Previous research has found a relationship between increased quantity of alcohol usually consumed per drinking occasion and decreased sober cognitive performance.
(5) "Yet the sobering fact remains that a transition to a low-carbon, inclusive green economy is happening far too slowly and the opportunity for meeting the 44 gigatonne target is narrowing annually," Steiner said.
(6) The haemostatic imbalance normalizes within two or three weeks of soberness while the immune system requires about two months to recover.
(7) Chambers claims she became extremely intoxicated while her ex-boyfriend remained much more sober, and says she has no memory of him having sex with her that night.
(8) Therefore, the presence of pulmonary emboli in association with sagittal sinus thrombosis mandates a sober assessment of the need of anticoagulation therapy in the absence of obvious contraindication.
(9) Mutual intoxication was a feature in 44% of the cases and in 34% both participants were sober.
(10) Impulsive and bonhomous, Saakashvili, meanwhile, is clearly the temperamental opposite of Putin, the sober and clinical former KGB colonel.
(11) Barton rubs Old Firm up the wrong way Joey Barton apologises ‘unreservedly’ after being sent home by Rangers Read more The phrase “Joey Barton Twitter storm” is pretty much a tautology, so it was no surprise that his decision to sign for Rangers in May had social media in a kerfuffle when his 2012 tweet – “I am a Celtic fan” – was dredged up so that it might be subject to calm and sober scrutiny from all concerned.
(12) And yet here I am today, a sober, emancipated, successful and happy woman.
(13) After all, on any sober calculation of relative sins, HSBC's dealings with Mexican drug bandits were surely several leagues more serious than other banks' Libor-rigging scandals.
(14) In the swinging 1960s, Peck's sober style seemed a little out of place, though he appeared in a couple of flashy Hitchcockian thrillers, Mirage (1965) and Arabesque (1966), and adapted to the new Hollywood as best he could, looking rather bothered as the father of a demon in The Omen (1976).
(15) Alcoholics reported more anger and aggression when drinking than when sober and this effect was greatest among individuals with a history of childhood aggression.
(16) She observed soberly that "the moment human beings lacked their own government and had to fall back upon their minimum rights, no authority was left to protect them and no institution was willing to guarantee them … Loss of national rights was identical with loss of human rights … The rights of man, supposedly inalienable, proved to be unenforceable … whenever people appeared who were no longer citizens of any sovereign state."
(17) It's not the most groundbreaking piece of research, but I did find it both instructive and sobering.
(18) In a year that will be punctuated by sober reflection and a series of commemorative occasions, it is tempting to assume a certain inevitability to events, especially when looking at them through the prism of hindsight.
(19) Even in alcoholics who have been sober for a long time, increased cardiac output is very common and these changes are similar to those seen in some patients with labile hypertension.
(20) He was a vegan, sober, nonsexual God-botherer partying in the blood-soaked Meatpacking District with the sex-and-druggers.