(superl.) Serious in feeeling or manner; sedate; grave; austere; not light, lively, or cheerful.
(superl.) Very strict in judgment, discipline, or government; harsh; not mild or indulgent; rigorous; as, severe criticism; severe punishment.
(superl.) Rigidly methodical, or adherent to rule or principle; exactly conformed to a standard; not allowing or employing unneccessary ornament, amplification, etc.; strict; -- said of style, argument, etc.
(superl.) Sharp; afflictive; distressing; violent; extreme; as, severe pain, anguish, fortune; severe cold.
(superl.) Difficult to be endured; exact; critical; rigorous; as, a severe test.
Example Sentences:
(1) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(2) The newborn with critical AS typically presents with severe cardiac failure and the infant with moderate failure, whereas children may be asymptomatic.
(3) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(4) The main clinical features pertaining to the concept of the "psycho-organic syndrome" (POS) were investigated in a sample of children who suffered from severe craniocerebral trauma.
(5) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
(6) Collins said she asked Sullivan several questions, including who the women were.
(7) Single-case experimental designs are presented and discussed from several points of view: Historical antecedents, assessment of the dependent variable, internal and external validity and pre-experimental vs experimental single-case designs.
(8) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
(9) Histological studies showed that the resulting pancreatitis was usually mild to moderate, being severe only in association with sepsis.
(10) An “out” vote would severely disrupt our lives, in an economic sense and a private sense.
(11) No consistent relationship could be found between the time interval from SAH to operation and the severity of vasospasm.
(12) Also we found that the lipid deposition in the glomeruli of patients with Alagille syndrome is related to an abnormal lipid metabolism, which is the consequence of severe cholestasis.
(13) Sixteen patients in whom schizophrenia was initially diagnosed and who were treated with fluphenazine enanthate or decanoate developed severe depression for a short period after the injection.
(14) Concentrations of several gastrointestinal hormonal peptides were measured in lymph from the cisterna chyli and in arterial plasma; in healthy, conscious pigs during ingestion of a meal.
(15) In addition to the changes associated with blood group A, we also found a decrease in sugar content, alterations in other antigens, and changes in the levels of several glycosyltransferases in cancerous tissues.
(16) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(17) The severity and site of hypertrophy is important in determining the clinical picture and the natural history of hypertrophic cardiomyopathy (HCM).
(18) After a discussion of the therapeutic relationship, several coping strategies which have been used successfully by many women are described and therapeutic applications are offered.
(19) To clarify the functional roles of His40, Glu58, and His92, we analyzed the consequences of several amino acid substitutions (His40Ala, His40Lys, His40Asp, Glu58Ala, Glu58Gln, and His92Gln) on the kinetics of GpC transesterification.
(20) Moreover, in DCVC-treated cells the mitochondria could not be stained with rhodamine-123, indicating severe mitochondrial damage and loss of membrane potential.
Sewer
Definition:
(n.) One who sews, or stitches.
(n.) A small tortricid moth whose larva sews together the edges of a leaf by means of silk; as, the apple-leaf sewer (Phoxopteris nubeculana)
(n.) A drain or passage to carry off water and filth under ground; a subterraneous channel, particularly in cities.
(n.) Formerly, an upper servant, or household officer, who set on and removed the dishes at a feast, and who also brought water for the hands of the guests.
Example Sentences:
(1) After visiting the H-blocks, the Catholic archbishop Cardinal Tomás Ó Fiaich compared the conditions to "the sewer pipes in the slums of Calcutta".
(2) Christmas 2013 caused 2,635 sewer blockages in Yorkshire alone.
(3) Soon, reformers known as “sanitarians” focused their attention on replacing the haphazard and unsanitary plumbing arrangements in homes and workplaces with technologically advanced public sewer systems.
(4) But nothing has been done about the stinking open sewers that run through the densely packed community and overflow whenever there is heavy rain.
(5) The use of self-topping aqua privies, discharging through sewers to oxidation ponds, has made possible the economic installation of water-carriage systems of waste disposal in low-cost high-density housing areas.In the oxidation ponds, typhoid bacteria appear to be more resistant than indicator organisms; helminths, cysts and ova settle out; there are no snails and, if peripheral vegetation is removed, mosquitos will not breed.
(6) Although the efficiency of the method was influenced by the composition and source of the sediments it was used successfully to detect viruses occurring in marine and freshwater sediments near sewer outfalls.
(7) In general, there is an improvement in chlorination, sewers and sewage-depuration equipment.
(8) Fatbergs build up on sewer roofs like mushy stalactites.
(9) In common usage, “myth” is at best the word we use to refer to amusingly preposterous urban legends – tales about albino alligators in the Manhattan sewers or the Holy Grail’s hiding place under the floor of a Paris shopping mall.
(10) No demographic risk factors were associated with the incidence of this disease including population density, median family income, crowding in housing units, percentage of households with public water supply, and percentage of households with public sewers.
(11) The apparent sources of these organisms were a residential storm sewer and a University of Wisconsin Experimental Farms' washwater drain.
(12) • Wipes, nappies, sanitary towels, rags and condoms do not break down easily and can snag on pipes, drains and the walls of sewers, leading to blockages.
(13) Inspection of the pool revealed significant plumbing defects which had allowed ingress of sewage from the main sewer into the circulating pool water.
(14) Paint and pesticides were disposed of by 10% of the households, but were dumped on the ground sewer or landfills more than 90% of the time.
(15) "So you've got open sewers, and shared toilets out in the open.
(16) Animals near the Los Angeles County sewer outfall contain over 45 times as much tDDT as animals near major agricultural drainage areas.
(17) But that’s for the future – a vast concrete sewer that may well be serviced by robots, or even drones.
(18) The effluent open sewer, situated in the north suburban district, drives into the sea the content of three maximum sewers that recollect domiciliary branches.
(19) They believed they wanted to take control and believed Britain would be better off … These kind of awful things are done by a minority who come from the sewers who want to exploit division and have their own racist agenda.” Map Halfon, who backed remain, added: “All of us need to stand up for tolerance and kindness and against any kind of division.” Police in Harlow have been given the power to order anyone involved in crime or harassment to leave The Stow.
(20) The effective energetic expenditure during a work shift was from 659 to 1020 kcal for weavers, from 740 to 1000 kcal for spinners and from 522 to 1105 kcal for sewers, which points to an uncomparable load at monomial workplaces equipped with different machines.