(superl.) Serious in feeeling or manner; sedate; grave; austere; not light, lively, or cheerful.
(superl.) Very strict in judgment, discipline, or government; harsh; not mild or indulgent; rigorous; as, severe criticism; severe punishment.
(superl.) Rigidly methodical, or adherent to rule or principle; exactly conformed to a standard; not allowing or employing unneccessary ornament, amplification, etc.; strict; -- said of style, argument, etc.
(superl.) Sharp; afflictive; distressing; violent; extreme; as, severe pain, anguish, fortune; severe cold.
(superl.) Difficult to be endured; exact; critical; rigorous; as, a severe test.
Example Sentences:
(1) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(2) The newborn with critical AS typically presents with severe cardiac failure and the infant with moderate failure, whereas children may be asymptomatic.
(3) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(4) The main clinical features pertaining to the concept of the "psycho-organic syndrome" (POS) were investigated in a sample of children who suffered from severe craniocerebral trauma.
(5) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
(6) Collins said she asked Sullivan several questions, including who the women were.
(7) Single-case experimental designs are presented and discussed from several points of view: Historical antecedents, assessment of the dependent variable, internal and external validity and pre-experimental vs experimental single-case designs.
(8) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
(9) Histological studies showed that the resulting pancreatitis was usually mild to moderate, being severe only in association with sepsis.
(10) An “out” vote would severely disrupt our lives, in an economic sense and a private sense.
(11) No consistent relationship could be found between the time interval from SAH to operation and the severity of vasospasm.
(12) Also we found that the lipid deposition in the glomeruli of patients with Alagille syndrome is related to an abnormal lipid metabolism, which is the consequence of severe cholestasis.
(13) Sixteen patients in whom schizophrenia was initially diagnosed and who were treated with fluphenazine enanthate or decanoate developed severe depression for a short period after the injection.
(14) Concentrations of several gastrointestinal hormonal peptides were measured in lymph from the cisterna chyli and in arterial plasma; in healthy, conscious pigs during ingestion of a meal.
(15) In addition to the changes associated with blood group A, we also found a decrease in sugar content, alterations in other antigens, and changes in the levels of several glycosyltransferases in cancerous tissues.
(16) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(17) The severity and site of hypertrophy is important in determining the clinical picture and the natural history of hypertrophic cardiomyopathy (HCM).
(18) After a discussion of the therapeutic relationship, several coping strategies which have been used successfully by many women are described and therapeutic applications are offered.
(19) To clarify the functional roles of His40, Glu58, and His92, we analyzed the consequences of several amino acid substitutions (His40Ala, His40Lys, His40Asp, Glu58Ala, Glu58Gln, and His92Gln) on the kinetics of GpC transesterification.
(20) Moreover, in DCVC-treated cells the mitochondria could not be stained with rhodamine-123, indicating severe mitochondrial damage and loss of membrane potential.
Spartan
Definition:
(a.) Of or pertaining to Sparta, especially to ancient Sparta; hence, hardy; undaunted; as, Spartan souls; Spartan bravey.
(n.) A native or inhabitant of Sparta; figuratively, a person of great courage and fortitude.
Example Sentences:
(1) When Nicolas Sarkozy held his first comeback rally, he sweated profusely on a small stage in a stuffy and spartan gymnasium in the south of France.
(2) They built spartan, concrete residential blocks on their remaining property, subdivided them into scores of tiny rooms and rented them out to migrant workers from the countryside.
(3) Simultaneous measurements of biochemical and physiological events of compensatory renal hypertrophy were made in groups of white Spartan rats.
(4) The very first inkling of what would be dubbed the Bristol sound was the Wild Bunch's spartan treatment of Bacharach and David's classic The Look of Love , released in 1988 on 4th & Broadway.
(5) The American author Jonathan Franzen might justly be called a perfectionist: his latest opus, Freedom, took nine years of painstaking effort to complete inside a spartan writing studio – and is now being widely acclaimed as a modern masterpiece.
(6) Gaskill’s Spartan staging of Macbeth, with Alec Guinness and Simone Signoret in 1966, received dreadful notices that led to a ferocious tussle with the London critics.
(7) Opened last year by the Irish Youth Hostel Association ( anoige.ie ), its somewhat institutional architecture, utilitarian concrete floors and Ikea furnishings may be too spartan for some, but the bright interiors and views of Glencree valley more than compensated.
(8) Alfred Parsons (1864-1952) was noted for his vigour of mind and body and Spartan habits and his dramatic teaching.
(9) Nevertheless, again, unusually "normally" for a royal, he attended school, even if it was the notoriously spartan Gordonstoun.
(10) George Jameson, rallying with Reclaim Australia in a replica Spartan military outfit, said they weren’t racists and had come together to stand up for freedom of speech.
(11) There's a suggestion the player will also take control of another Spartan investigating the series hero – more on that later.
(12) His later years, as the preachments of abolitionists and slaveholders reached their shrill adumbration of bloody war, were marked, even made notorious, by his fiery championing of John Brown, whom he had briefly met in Concord, finding him "a man of great common sense, deliberate and practical", endowed with "tact and prudence" and the Spartan habits and spare diet of a soldier.
(13) The episode is illustrative of Sontag's emotionally spartan childhood, which produced a self-contained but not insular child.
(14) Orwell's letters were bucolic - lots of stuff about horses, flowers and fishing - but the references to the house suggest that 'spartan' may be too generous a description.
(15) For now, Halo spin-off Halo: Spartan Assault remains exclusive to Windows-powered device.
(16) *** Five hours before the People’s PPE meeting, I pitch up at a grim-looking office block next to Euston station, buzz the entry phone and go up a couple of flights of stairs into a warren of spartan rooms.
(17) 10.10am: Barry Glendenning's paper view has arrived to round up the Fourth Estate's perspective this morning: In the Mirror, Oliver Holt is busily fighting John Terry's corner, claiming that the former skipper deserves credit, not opprobium, for being the only England player prepared to speak out about the "spartan regime they have been living under for the last five weeks".
(18) Apart, perhaps, from Skipper's spartan office which looks out over a car park and the windowless neighbouring building of the department of work and pensions.
(19) It was here that he refined his incomparable talent for drawing, but in his early years he was drawn to history painting – young Spartans , Semiramis – and the dreamy style of symbolists such as Pierre Puvis de Chavannes and Gustave Moreau .
(20) It portrays the heroic endeavours of 300 Spartans, under King Leonidas, who are shown resisting an invading force of 120,000 Persian troops led by Emperor Xerxes.