(superl.) Serious in feeeling or manner; sedate; grave; austere; not light, lively, or cheerful.
(superl.) Very strict in judgment, discipline, or government; harsh; not mild or indulgent; rigorous; as, severe criticism; severe punishment.
(superl.) Rigidly methodical, or adherent to rule or principle; exactly conformed to a standard; not allowing or employing unneccessary ornament, amplification, etc.; strict; -- said of style, argument, etc.
(superl.) Sharp; afflictive; distressing; violent; extreme; as, severe pain, anguish, fortune; severe cold.
(superl.) Difficult to be endured; exact; critical; rigorous; as, a severe test.
Example Sentences:
(1) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(2) The newborn with critical AS typically presents with severe cardiac failure and the infant with moderate failure, whereas children may be asymptomatic.
(3) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(4) The main clinical features pertaining to the concept of the "psycho-organic syndrome" (POS) were investigated in a sample of children who suffered from severe craniocerebral trauma.
(5) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
(6) Collins said she asked Sullivan several questions, including who the women were.
(7) Single-case experimental designs are presented and discussed from several points of view: Historical antecedents, assessment of the dependent variable, internal and external validity and pre-experimental vs experimental single-case designs.
(8) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
(9) Histological studies showed that the resulting pancreatitis was usually mild to moderate, being severe only in association with sepsis.
(10) An “out” vote would severely disrupt our lives, in an economic sense and a private sense.
(11) No consistent relationship could be found between the time interval from SAH to operation and the severity of vasospasm.
(12) Also we found that the lipid deposition in the glomeruli of patients with Alagille syndrome is related to an abnormal lipid metabolism, which is the consequence of severe cholestasis.
(13) Sixteen patients in whom schizophrenia was initially diagnosed and who were treated with fluphenazine enanthate or decanoate developed severe depression for a short period after the injection.
(14) Concentrations of several gastrointestinal hormonal peptides were measured in lymph from the cisterna chyli and in arterial plasma; in healthy, conscious pigs during ingestion of a meal.
(15) In addition to the changes associated with blood group A, we also found a decrease in sugar content, alterations in other antigens, and changes in the levels of several glycosyltransferases in cancerous tissues.
(16) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(17) The severity and site of hypertrophy is important in determining the clinical picture and the natural history of hypertrophic cardiomyopathy (HCM).
(18) After a discussion of the therapeutic relationship, several coping strategies which have been used successfully by many women are described and therapeutic applications are offered.
(19) To clarify the functional roles of His40, Glu58, and His92, we analyzed the consequences of several amino acid substitutions (His40Ala, His40Lys, His40Asp, Glu58Ala, Glu58Gln, and His92Gln) on the kinetics of GpC transesterification.
(20) Moreover, in DCVC-treated cells the mitochondria could not be stained with rhodamine-123, indicating severe mitochondrial damage and loss of membrane potential.
Suffocate
Definition:
(a.) Suffocated; choked.
(v. t.) To choke or kill by stopping respiration; to stifle; to smother.
(v. t.) To destroy; to extinguish; as, to suffocate fire.
(v. i.) To become choked, stifled, or smothered.
Example Sentences:
(1) In his only specific growth measure, he said Britain's planning laws would have to be scrapped so more housing could be built, vowing to scrap "the suffocating bureaucracy" that he said was holding economic growth back.
(2) Because of inspiration into the tracheo-bronchial aireays, regurgitation from purely oesophageal diseases can provoke various respiratory affections: acute broncho-pulmonary blocking broncho-pneumonia, pulmonary suppuration, night cough, fits of nocturnal suffocation, chronic bronchitis sometimes hemoptic.
(3) An orderly process of dealing with asylum claims at the earliest point would be infinitely preferable to desperate families laying siege to central European railway stations, risking their lives clinging on to vehicles at Calais or suffocating in vehicles transporting them across borders.
(4) If any of them is neglected or isolated from the rest, the whole will be impoverished-the student will suffocate in disconnected, empirical facts; fanciful theories will be spun from tenuous evidence; well established theory will be neglected by the practitioner; the best-intentioned schemes will have disastrous long-term consequences.
(5) But his growing band of critics fear the suffocation of democracy and human rights.
(6) There is nothing he said which could be understood as an incitement to violence, and nothing which is not obviously true, and commonplace outside the squalid little dogma that suffocates the human spirit in Saudi.
(7) On day one, we were almost stampeded by elephants, and I had to suffocate a goat and then drink its blood directly from the jugular.
(8) I marvel now at how he learned to anchor himself – physically and mentally – in that suffocating darkness.
(9) This trip to Basel should, in theory, be as tough as it gets and that layer of insurance may have helped Hodgson’s team to play without feeling too suffocated by external pressures.
(10) In sum, we will render impotent the government's efforts to use its coercive pressure over corporations to suffocate not only WikiLeaks but any other group it may similarly target in the future.
(11) Every weekend ... you end up getting suffocated by what happens on the football field.
(12) "We are so used to seeing one idea of what a young man or woman is in the popular media," she says, adding that it is "suffocating" how homogeneously young people are represented on screen.
(13) Patients with advanced esophageal carcinoma with tracheobronchial obstruction usually present with severe dyspnea or hemoptysis or both and may die of suffocation.
(14) His head pounds, “my chest gets heavy, stomach gets tight” and “I feel suffocated, anxious.” “I have difficulty breathing at the end of the day, my face is black with soot,” says Kumar, waiting for his next fare on a noisy corner in south Delhi, beside a road jammed with honking cars, trucks and buses.
(15) The notoriously suffocating tone of the 50th anniversary in 1966, when veterans of 1916 were still alive and the all-Ireland republic was treated as unfinished business, has been replaced by a more open and inclusive approach today, as the rising recedes into history, though without diminishing its narrative potency.
(16) From 1 January, residents in India’s capital city, which had been suffocating under a blanket of smog in recent days, will only be able to drive on alternate days based on their licence plate number; odd numbers on one day, even on the other.
(17) Some were related to age group specific behaviour, such as drownings and falls in young children and suffocations in infants.
(18) But is it really so bad that Lydia refuses to conform to the strict and suffocating conventions of female propriety?
(19) She died of the suffocation caused by bronchopneumonia at the age of 60 years.
(20) With Greece suffocating under capital controls and the banks fighting for survival under a mountain of bad debt, a main focus of the bailout programme is saving and reviving the banking sector through the recapitalisation of ailing financial institutions.