(superl.) Serious in feeeling or manner; sedate; grave; austere; not light, lively, or cheerful.
(superl.) Very strict in judgment, discipline, or government; harsh; not mild or indulgent; rigorous; as, severe criticism; severe punishment.
(superl.) Rigidly methodical, or adherent to rule or principle; exactly conformed to a standard; not allowing or employing unneccessary ornament, amplification, etc.; strict; -- said of style, argument, etc.
(superl.) Sharp; afflictive; distressing; violent; extreme; as, severe pain, anguish, fortune; severe cold.
(superl.) Difficult to be endured; exact; critical; rigorous; as, a severe test.
Example Sentences:
(1) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(2) The newborn with critical AS typically presents with severe cardiac failure and the infant with moderate failure, whereas children may be asymptomatic.
(3) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(4) The main clinical features pertaining to the concept of the "psycho-organic syndrome" (POS) were investigated in a sample of children who suffered from severe craniocerebral trauma.
(5) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
(6) Collins said she asked Sullivan several questions, including who the women were.
(7) Single-case experimental designs are presented and discussed from several points of view: Historical antecedents, assessment of the dependent variable, internal and external validity and pre-experimental vs experimental single-case designs.
(8) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
(9) Histological studies showed that the resulting pancreatitis was usually mild to moderate, being severe only in association with sepsis.
(10) An “out” vote would severely disrupt our lives, in an economic sense and a private sense.
(11) No consistent relationship could be found between the time interval from SAH to operation and the severity of vasospasm.
(12) Also we found that the lipid deposition in the glomeruli of patients with Alagille syndrome is related to an abnormal lipid metabolism, which is the consequence of severe cholestasis.
(13) Sixteen patients in whom schizophrenia was initially diagnosed and who were treated with fluphenazine enanthate or decanoate developed severe depression for a short period after the injection.
(14) Concentrations of several gastrointestinal hormonal peptides were measured in lymph from the cisterna chyli and in arterial plasma; in healthy, conscious pigs during ingestion of a meal.
(15) In addition to the changes associated with blood group A, we also found a decrease in sugar content, alterations in other antigens, and changes in the levels of several glycosyltransferases in cancerous tissues.
(16) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(17) The severity and site of hypertrophy is important in determining the clinical picture and the natural history of hypertrophic cardiomyopathy (HCM).
(18) After a discussion of the therapeutic relationship, several coping strategies which have been used successfully by many women are described and therapeutic applications are offered.
(19) To clarify the functional roles of His40, Glu58, and His92, we analyzed the consequences of several amino acid substitutions (His40Ala, His40Lys, His40Asp, Glu58Ala, Glu58Gln, and His92Gln) on the kinetics of GpC transesterification.
(20) Moreover, in DCVC-treated cells the mitochondria could not be stained with rhodamine-123, indicating severe mitochondrial damage and loss of membrane potential.
Urgent
Definition:
(a.) Urging; pressing; besetting; plying, with importunity; calling for immediate attention; instantly important.
Example Sentences:
(1) This case demonstrates that the manifestations may be delayed and that urgent surgical intervention may be lifesaving despite the precarious status of these patients.
(2) Enright said: “We call on the home secretary and chair of IICSA [the independent inquiry into child sexual abuse] to engage actively and urgently to find a way forward that secures the confidence of survivors and provides the inquiry’s legal team with the resources and support they need to deliver justice and truth that survivors deserve.” Stein said his clients were “deeply disatisfied” with aspects of how the inquiry had been conducted but called for Emmerson to stay, adding: “I urge the home secretary to seek to find a way in which his valuable contribution can be maintained”.
(3) We are urgently investigating this incident with our supplier and ask customers to return this product to their local store."
(4) The patient presented urgently for Caesarean section, with fluid overload and worsening thrombocytopaenia.
(5) Their confidence in the practitioner's clinical judgment was greater in their care of nonurgent and urgent patients.
(6) The pope has written in his encyclical of the urgent need to reduce climate change gases.
(7) Zoellick was also clear that action was now urgently needed.
(8) The following year yet another Bank analyst wrote a report on BCCI entitled "Why action is now urgently required".
(9) And we owe [Hickox] better than that and all the people who do this work better than that.” The White House indicated that it was urgently reviewing the federal guidelines for returning healthcare workers, “recognising that these medical professionals’ selfless efforts to fight this disease on the front lines will be critical to bringing this epidemic under control, the only way to eliminate the risk of additional cases here at home”.
(10) The urgent endoscopy of the superior gastrointestinal haemorrhage carefully and quickly helps in clarifying the following questions: Is the patient going on bleeding?
(11) Close cooperation of ophthalmological departments with vitreoretinal centres and early performance of urgent surgery are the basic prerequisites of better functional results of PPV in EHE.
(12) "Ministers must urgently get behind a different approach to food and farming that delivers real sustainable solutions rather than peddling the snake oil that is GM ."
(13) Urinary frequency was normalized in 6 out of 16 (37.5%), urgency ceased in 6 out of 17 (35.7%) and urgent incontinence disappeared in 9 out of 14 (50%) patients.
(14) This issue should attract attention more urgently now in light of the deaths in Savar.
(15) Guide-wire fragments retained in the coronary artery system after PTCA are removed either immediately by means of catheter techniques or by urgent operation.
(16) Ownership is not the problem, affordable homes for people are what are urgently needed and will, it seems, need a new government.
(17) It is understood that counterterrorism police at Heathrow are urgently seeking a meeting with senior UKBA management over the missed alerts.
(18) Alongside investment in health campaigns to help people reduce their risk of cancer, the government urgently needs to take action to stop children starting smoking by introducing standardised packaging for cigarettes without delay”, he added.
(19) Four of the six related deaths and half the urgent operations occurred among 18 patients iwth colonic dilatation.
(20) The other two patients underwent urgent adrenalectomy and had postoperative improvement in their multiple organ system failure.