(n.) A sign made for the purpose of giving notice to a person of some occurence, command, or danger; also, a sign, event, or watchword, which has been agreed upon as the occasion of concerted action.
(n.) A token; an indication; a foreshadowing; a sign.
(a.) Noticeable; distinguished from what is ordinary; eminent; remarkable; memorable; as, a signal exploit; a signal service; a signal act of benevolence.
(a.) Of or pertaining to signals, or the use of signals in conveying information; as, a signal flag or officer.
(v. t.) To communicate by signals; as, to signal orders.
(v. t.) To notify by a signals; to make a signal or signals to; as, to signal a fleet to anchor.
Example Sentences:
(1) Such a signal must be due to a small ferromagnetic crystal formed when the nerve is subjected to pressure, such as that due to mechanical injury.
(2) Glucocorticoids have numerous effects some of which are permissive; steroids are thus important not only for what they do, but also for what they permit or enable other hormones and signal molecules to do.
(3) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(4) Theresa May signals support for UK-EU membership deal Read more Faull’s fix, largely accepted by Britain, also ties the hands of national governments.
(5) Type 1 changes (decreased signal intensity on T1-weighted spin-echo images and increased signal intensity on T2-weighted images) were identified in 20 patients (4%) and type 2 (increased signal intensity on T1-weighted images and isointense or slightly increased signal intensity on T2-weighted images) in 77 patients (16%).
(6) The presently available data allow us to draw the following conclusions: 1) G proteins play a mediatory role in the transmission of the signal(s) generated upon receptor occupancy that leads to the observed cytoskeletal changes.
(7) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(8) The region containing the injection stop signal (iss) has been cloned and sequenced and found to contain numerous large repeats and inverted repeats which may be part of the iss.
(9) Here, we review the nature of the heart sound signal and the various signal-processing techniques that have been applied to PCG analysis.
(10) The present study was designed to test the hypothesis that the decreased Epi response following ET was due to 1) depletion of adrenal Epi content such that adrenomedullary stimulation would not release Epi, 2) decreased Epi release with direct stimulation, i.e., desensitization of release, or 3) decreased afferent signals generated by ET itself.
(11) In documents due to be published by the bank, it will signal a need to shed costs from a business that employs 10,000 people as it scrambles to return to profit.
(12) In fact, you might read it as a signal … that the president might well lose on this,” she said.
(13) Further study both of the signaling events that lead to MPF activation and of the substrates for phosphorylation by MPF should lead to a comprehensive understanding of the biochemistry of cell division.
(14) After several months, a temporal discrimination was well established, as shown by maximum suppression toward the end of the signal period.
(15) 2010 2 May : In a move that signals the start of the eurozone crisis, Greece is bailed out for the first time , after eurozone finance ministers agree to grant the country rescue loans worth €110bn (£84bn).
(16) Protein kinase C (PKC) is activated rapidly and transiently following ionizing radiation exposure and is postulated to activate downstream nuclear signal transducers.
(17) During that time they have repeatedly demonstrated the likely existence of signalling molecules or morphogens that control the pattern of development in the embryo.
(18) Recently, we have designed a series of simplified artificial signal sequences and have shown that a proline residue in the signal sequence plays an important role in the secretion of human lysozyme in yeast, presumably by altering the conformation of the signal sequence [Yamamoto, Y., Taniyama, Y., & Kikuchi, M. (1989) Biochemistry 28, 2728-2732].
(19) After calving, probably the position of new follicles is temporally influenced by direct signals from the uterine horns affected differently by pregnancy.
(20) The purpose of the present study was to investigate whether the signaling behaviors of female Long-Evans rats varies over the estrous cycle.
Target
Definition:
(n.) A kind of small shield or buckler, used as a defensive weapon in war.
(n.) A butt or mark to shoot at, as for practice, or to test the accuracy of a firearm, or the force of a projectile.
(n.) The pattern or arrangement of a series of hits made by a marksman on a butt or mark; as, he made a good target.
(n.) The sliding crosspiece, or vane, on a leveling staff.
(n.) A conspicuous disk attached to a switch lever to show its position, or for use as a signal.
Example Sentences:
(1) The resulting dose distribution is displayed using traditional 2-dimensional displays or as an isodose surface composited with underlying anatomy and the target volume.
(2) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(3) The fraction of the viral dose which became cell associated was independent of the incubation temperature and increased with increasing target membrane concentration.
(4) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(5) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(6) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(7) After midazolam infusion, there was a 50% decrease in amplitude of P3 in response to target tones (P less than 0.006), whereas N3 latency increased by 40 ms (P less than 0.05).
(8) In the absence of an authentic target for the MASH proteins, we examined their DNA binding and transcriptional regulatory activity by using a binding site (the E box) from the muscle creatine kinase (MCK) gene, a target of MyoD.
(9) Despite a 10-year deadline to have the same number of ethnic minority officers in the ranks as in the populations they serve, the target was missed and police are thousands of officers short.
(10) A 24-h test trial employing a dry target demonstrated a robust memory for the training manifested in passive avoidance behavior.
(11) For related pairs, both the primes (first pictures) and targets (second pictures) varied in rated "typicality" (Rosch, 1975), being either typical or relatively atypical members of their primary superordinate category.
(12) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(13) Charge data from the target hospital showed a statistically significant reduction in laboratory charges per patient in the quarter following program initiation (P = 0.02) and no evidence for change in a group of five comparison hospitals.
(14) Consequently, it is important to predict accurately dose for such fields to ensure adequate coverage of the target region and sparing of healthy tissues.
(15) Three effector: target ratios (6.2:1, 25:1, and 50:1) were studied in quadruplicate using 3, 4 and 5-h incubations.
(16) It is proposed that microoscillations of the eye increase the threshold for detection of retinal target displacements, leading to less efficient lateral sway stabilization than expected, and that the threshold for detection of self motion in the A-P direction is lower than the threshold for object motion detection used in the calculations, leading to more efficient stabilization of A-P sway.
(17) However, since these levels were unaltered by reducing the antiandrogen dosage, the main action of the therapy is probably that of the antiandrogen within the target cells.
(18) We are pleased to see the process moving forward and look forward to its resolution,” a Target spokeswoman, Molly Snyder, said in an emailed statement.
(19) The matter is now in the hands of the Guernsey police and the law officers.” One resident who is a constant target of the paper and has complained to police, Rosie Guille, said the allegations had a “huge impact on morale” on the island.
(20) This article describes a method of selecting a potentially successful strategy using a combination of two factors: change target and level of change willingness and ability.