(v. i.) To take rest by a suspension of the voluntary exercise of the powers of the body and mind, and an apathy of the organs of sense; to slumber.
(v. i.) To be careless, inattentive, or uncouncerned; not to be vigilant; to live thoughtlessly.
(v. i.) To be dead; to lie in the grave.
(v. i.) To be, or appear to be, in repose; to be quiet; to be unemployed, unused, or unagitated; to rest; to lie dormant; as, a question sleeps for the present; the law sleeps.
(v. t.) To be slumbering in; -- followed by a cognate object; as, to sleep a dreamless sleep.
(v. t.) To give sleep to; to furnish with accomodations for sleeping; to lodge.
(v. i.) A natural and healthy, but temporary and periodical, suspension of the functions of the organs of sense, as well as of those of the voluntary and rational soul; that state of the animal in which there is a lessened acuteness of sensory perception, a confusion of ideas, and a loss of mental control, followed by a more or less unconscious state.
(1) AEDs may also have differential effects on nighttime sleep.
(2) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
(3) For assessment of clinical status, investigators must rely on the use of standardized instruments for patient self-reporting of fatigue, mood disturbance, functional status, sleep disorder, global well-being, and pain.
(4) We investigated whether these peptides also affect the sleep EEG in humans when given intravenously by comparing polysomnographically the effects of four boluses of (1) placebo, (2) 50 micrograms GHRH or (3) 50 micrograms SRIF administered at 22.00, 23.00, 24.00 and 1.00 h to 7 male controls.
(5) Polygraphic recordings during sleep were performed on 18 elderly persons (age range: 64-100 years).
(6) This was carried out on the healthy subjects for a total of 12 nights without medication (control nights asleep), a total of 12 nights following 40 mg of flucortolone the previous morning, and a total of 6 nights with similar blood sampling when sleep was prevented (control nights awake).
(7) Although temazepam was effective for maintaining sleep with short-term use, there was rapid development of tolerance for this effect with intermediate-term use.
(8) The occurrence of episodes of desaturation during sleep in patients suffering from chronic airflow obstruction is well known.
(9) A lower than normal percentage of REM sleep in these patients was consistent with their retarded intellectual development, which supports current thinking that REM sleep may be a sensitive index of brain function integrity.
(10) Amine metabolites, 5-hydroxyindoleacetic acid (5HIAA), and homovanillic acid (HVA) were not substantially affected by sleep deprivation, although there was a significant interaction of clinical response and direction of 3-methoxy-4-hydroxyphenylglycol (MHPG) change.
(11) Results of sleep sampling under electroencephalographic control of the assessment of GH secretion are comparable to conventional pharmacological studies in terms of efficiency, sensitivity, and percentage false-negatives.
(12) Sleep was defined behaviorally as failure to respond to the faint auditory RT cue.
(13) We have evaluated the action of hypnotics on the sleep-wakefulness cycle in freely implanted rats during their maximally active period because it is easier to estimate the duration of the sedative effect.
(14) However, patients can be taught how to retard the onset of wrinkles by avoiding unprotected sun exposure, unnecessary facial movements, and certain sleeping positions.
(15) The analogy with infant sleep patterns and results of studies of brain function in narcoleptics suggest that forebrain inhibitory processes are more important in narcoleptic symptomology than is brainstem dysfunction.
(16) In short term clinical studies, the beneficial effects of transdermal estradiol on plasma gonadotrophins, maturation of the vaginal epithelium, metabolic parameters of bone resorption and menopausal symptoms (hot flushes, sleep disturbance, genitourinary discomfort and mood alteration) appear to be comparable to those of oral and subcutaneous estrogens, while the undesirable effects of oral estrogens on hepatic metabolism are avoided.
(17) Sleep alterations in addicted newborns could be related to central nervous system (CNS) distress caused by withdrawal.
(18) "Our black, Muslim and Jewish citizens will sleep much less easily now the BBC has legitimised the BNP by treating its racist poison as the views of just another mainstream political party when it is so uniquely evil and dangerous."
(19) Stage REM frequently appeared within 10 min of stage 1 onset and the normal sequence of stages REM and 4 were altered, demonstrating that the organization of sleep within a nap is quite different from that in monophasic nocturnal sleep.
(20) This result is discussed in terms of either a function of time-of-day effect or of prior sleep intensity.
(a.) Causing sleep; tending to cause sleep; soporiferous; as, the soporific virtues of opium.
(n.) A medicine, drug, plant, or other agent that has the quality of inducing sleep; a narcotic.
(1) The maximum soporific effect did not occur until 90-120 s after injection.
(2) His answer threatened a soporific summer-long contest that would expose a great gap between the self-styled people's party and the people themselves.
(3) 'P ublic sector commissioning": I can't think of a phrase that conveys something so important and yet sounds so soporific.
(4) Soporific effect of hexenal was distinctly increased in the burns, which correlated to the severity of thermic impairment.
(5) Pebble-dashed walls, red roof tiles, Velux windows, cherry trees... these things make me think not of daring strokes of oil on canvas, but of the safe, the soporific - a round of golf, perhaps, or a gentle Sunday-night sitcom.
(6) Less drugs were used in general, and the use of tranquillizers and soporifics was cut down to a third.
(7) Higher doses of naloxone (1Opmol into the LC) were however, required to antagonize the behavioural and ECoG soporific effects induced by the Kappa-receptor agonist U 50,488H.
(8) The drug is well tolerated by the patients and does not produce any inhibitory or soporific action.
(9) And, intriguingly, a 2009 study at Mashhad University in Iran revealed an extract of saffron did have soporific qualities, on mice at least.
(10) Instead, the atmosphere is soporific, with an underlying threat of menace.
(11) Toxicological urine analysis for drugs--directed mainly at soporifics, sedatives, tranquilizers, and pain-relievers--on 84 patients involved in industrial accidents yielded the following results.
(12) What had been a sombre occasion for City fans as they looked at an Etihad Stadium dugout without Mancini for a first time since December 2009 became further muted when a soporific start to the game had ended with Anthony Pilkington opening the scoring for Norwich.
(13) 1 Experiments were performed on a variety of tissues from different species to establish whether or not the properties of p-chlorophenylalanine methyl ester (PCPA) included a 5-hydroxytryptamine (5-HT)-like action which might explain the soporific action of PCPA in chicks.
(14) Because of their pharmacologic action, alcohol and high doses of soporifics used as remedies may produce REM-deficit sleep and actually prolong insomnia.
(15) Imagine my surprise in the morning to find it was gone 7am – the soporific effect of the loud snoring made my baby sleep through the night for the first time!
(16) Long sleep (LS) and short sleep (SS) mice have a differential sensitivity to the behavioral actions of an adenosine agonist, R-phenylisopropyl-adenosine (PIA) that parallels their differential sensitivity to the soporific effects of ethanol.
(17) If so, the soporific way Per Mertesacker dawdled in possession and Kieran Gibbs clumsily punted the ball into the air suggested there had been scant impact.
(18) After 53 days of alcohol ingestion there was no evidence of tolerance to the soporific effects of parenterally administered ethanol and removal of the ethanol solutions failed to produce any signs of alcohol withdrawal.
(19) Further, much evidence also supports the conclusion that most of these hypnotic-depressants and anesthetics could exert their soporific influence by a potentiation of GABA activity.
(20) Recent evidence, as well as reevaluated previous evidence, indicates that Long-Sleep mice are more sensitive to the soporific effects of three major classes of CNS depressants (alcohols, barbiturates, and benzodiazepines), as well as many other anesthesia-inducing compounds (adenosine, chloral hydrate, trichloroethanol, paraldehyde, nitrous oxide, enflurane, and isoflurane).