(superl.) Having an even surface, or a surface so even that no roughness or points can be perceived by the touch; not rough; as, smooth glass; smooth porcelain.
(superl.) Evenly spread or arranged; sleek; as, smooth hair.
(superl.) Gently flowing; moving equably; not ruffled or obstructed; as, a smooth stream.
(superl.) Flowing or uttered without check, obstruction, or hesitation; not harsh; voluble; even; fluent.
(superl.) Bland; mild; smoothing; fattering.
(superl.) Causing no resistance to a body sliding along its surface; frictionless.
(adv.) Smoothly.
(n.) The act of making smooth; a stroke which smooths.
(n.) That which is smooth; the smooth part of anything.
(a.) To make smooth; to make even on the surface by any means; as, to smooth a board with a plane; to smooth cloth with an iron.
(a.) To free from obstruction; to make easy.
(a.) To free from harshness; to make flowing.
(a.) To palliate; to gloze; as, to smooth over a fault.
(a.) To give a smooth or calm appearance to.
(a.) To ease; to regulate.
(v. i.) To flatter; to use blandishment.
Example Sentences:
(1) These immunocytochemical studies clearly demonstrated that cells encountered within the fibrous intimal thickening in the vein graft were inevitably smooth muscle cell in origin.
(2) Thus adrenaline, via pre- and post-junctional adrenoceptors, may contribute to enhanced vascular smooth muscle contraction, which most likely is sensitized by the elevated intracellular calcium concentration.
(3) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(4) Peripheral eosinocytes increased by 10%, and tests for HBsAg, antiHBs, antimitochondrial antibody and anti-smooth muscle antibody were all negative.
(5) After vascular injury, smooth muscle cells proliferate, reaching a maximum rate at day 2.
(6) Recent studies have shown that an aberration in platelet-derived growth factor gene expression is unlikely to be a factor in proliferation of smooth-muscle cells.
(7) The Ta loop was a smooth, elongated ellipse in configuration and showed clockwise rotation in all planes, as did the P loop.
(8) This series of tests included tests for pathologic nystagmus, saccades, smooth pursuit, and optokinetic nystagmus, as well as bithermal caloric testing and rotational testing.
(9) It inhibits platelet and vascular smooth muscle activation by cGMP-dependent attenuation of the agonist-induced rise of intracellular free Ca2+.
(10) It is concluded that a Na-H antiport system in vascular smooth muscle regulates Na influx rate, contributes to intracellular pH regulation and influences basal levels of Na,K-pump activity.
(11) By 30 min after insemination, the surface of the egg is relatively smooth.
(12) An electrogenic sodium-potassium pump appears to contribute materially to the steady-state potential and to certain of the transient potential responses of vascular smooth muscle.
(13) Distribution patterns of phosphatidylserine and phosphatidylinositol in the smooth muscle as well as in the mucosa were different from those in the liver.
(14) Ultrastructural study of the uterine lesion demonstrated smooth muscle cells with only a few "autophagic" facuoles to cells nearly replaced by lysosomes.
(15) These early hyperplastic lesions revealed stellate-shaped dilated bile canaliculi lined by blebs and abnormally thick elongated microvilli, a decreased number of microvilli on the sinusoidal surface, a marked increase in smooth endoplasmic reticulum, large nucleoli, and bundles of pericanalicular microfilaments.
(16) We conclude that once daily doxazosin provides smooth and effective blood pressure control throughout a 24 h post-dose period.
(17) It is suggested that contractile responses to electrical stimulation in isolated sheep urethral smooth muscle are mediated by the sympathetic nervous system, mainly through release of noradrenaline stimulating postjunctional alpha 1-adrenoceptors.
(18) Four fractions enriched, respectively, in plasma membrane (PM), smooth endoplasmic reticulum (SER), rough endoplasmic reticulum (RER), and mitochondria were isolated from estrogen-dominated rat myometrium.
(19) From the findings of this study the authors recommend wide excision of colorectal smooth-muscle tumours whenever there is a suggestion of malignancy.
(20) All smooth strains of Brucella bear two lipopolysaccharide (LPS) antigens in a ratio that defines the classification of strains in serovars, A (A greater than M), M (M greater than A) and A.M (A = M).
Sophisticated
Definition:
(imp. & p. p.) of Sophisticate
(a.) Adulterated; not pure; not genuine.
Example Sentences:
(1) "With the advent of sophisticated data-processing capabilities (including big data), the big number-crunchers can detect, model and counter all manner of online activities just by detecting the behavioural patterns they see in the data and adjusting their tactics accordingly.
(2) A developing sophistication on the part of both children and parents, coupled with a rapidly expanding recognition of the need to minimize the amount of physical and psychological trauma that a child has to experience, has led to a growing use of premedication agents for children.
(3) The initial defect can be directly measured by glucose clamp and other sophisticated techniques; the clinical syndrome may be derived from a network of related variables known to be associated with reduced insulin action.
(4) While simple assays of complex I activity are unlikely to be useful in the preclinical detection of Parkinson's disease, other more sophisticated physical-chemical approaches including detection of free radical damage may have utility.
(5) This is not some sophisticated, Westminstery battle, but a life-and-death, misery-or-decency choice about the very basics of life for hundreds of thousands of older British people.
(6) While the high sophistication subjects rated the interpretation as accurate across validity conditions, the low sophistication subjects rated the interpretation according to the validity instructions they received.
(7) Lateralization may be an expression of reflex constraints bound initially to the infant's tonic-neck posture, with later development less reflex-patterned during the acquisition of more sophisticated information-processing strategies.
(8) A simple multiband volume control is expected to provide much of the benefit of more sophisticated systems without the need for separate estimation of input speech and noise spectra.
(9) What’s imperative from an organizational standpoint, he added, is “understanding where voters are, what their concerns are, and building a sophisticated operation around that.
(10) The laws of functioning applicable to these approaches are those coming from liberal and planified economical theories while health planning has developed more and more sophisticated and convincing methodologies.
(11) Therefore, controlled hypotension, being a sophisticated technique, requires handling by an experienced anesthetist well aware of contraindications and the need for adequate monitoring for prevention of tissue ischemia.
(12) However, a homemade pipe bomb thrown at a police patrol in north Belfast earlier this year was described as of a new, sophisticated variety that the PSNI had not seen before.
(13) While numerous studies on infant perception have demonstrated the infant's ability to discriminate sounds having different frequencies, little research has evaluated more sophisticated pitch perception abilities such as perceptual constancy and perception of the missing fundamental.
(14) It is concluded that imaging of the urinary tract is not necessary for pure nightwetters, while ultrasonography or uroflowmetry and more sophisticated radiological or urological methods should be focused on those children with daytime wetting and clinical symptoms of voiding disturbances.
(15) When multiple database systems are present, a flexible front end can provide sophisticated querying capabilities that bridge the systems, while hiding the complexities of the multiple systems from the user.
(16) This validity coefficient turned out to be so high (r = 0.967) that it does not seem necessary to adopt a more sophisticated method, despite a few demonstrable shortcomings of the one in use.
(17) The comparison of drug responder and non-responder group has also been made more meaningful by the availability of more reliable methods of assessing clinical phenomena, more sophisticated diagnostic models and the introduction of other biological measures.
(18) The environment in the intensive therapy units (ITUs) has thus become increasingly sophisticated with the use of highly specialised equipment.
(19) Attempts to save parts of teeth go back 100 years or more, but it is the increased predictability of success of endodontic therapy and the increased sophistication of periodontal treatment that have given us the means to save molars with furcation problems that, otherwise, would be lost.
(20) The monitoring equipment gets more sophisticated and easier to use month by month.