(v. t.) To soak in a liquid; to macerate; to extract the essence of by soaking; as, to soften seed by steeping it in water. Often used figuratively.
(v. i.) To undergo the process of soaking in a liquid; as, the tea is steeping.
(n.) Something steeped, or used in steeping; a fertilizing liquid to hasten the germination of seeds.
(n.) A rennet bag.
(v. t.) Making a large angle with the plane of the horizon; ascending or descending rapidly with respect to a horizontal line or a level; precipitous; as, a steep hill or mountain; a steep roof; a steep ascent; a steep declivity; a steep barometric gradient.
(v. t.) Difficult of access; not easy reached; lofty; elevated; high.
(v. t.) Excessive; as, a steep price.
(n.) A precipitous place, hill, mountain, rock, or ascent; any elevated object sloping with a large angle to the plane of the horizon; a precipice.
Example Sentences:
(1) The dose response effect in this tumor is steep and combinations which compromise the dose of adriamycin too greatly are showing inferior results.
(2) Steep longitudinal and transverse gradients of glycogen are known to exist in the organ of Corti of the guinea pig, with preferential accumulation in the outer hair cells of the apical turns.
(3) The steep portion of the relationship between Retzius cell action potential amplitude and membrane potential extrapolated to an apparent reversal potential of -13 mV.
(4) This property of endotoxin can serve as a sensitive bioassay, although the dose-response curve is steep.
(5) With its steep hills and cobblestones, the neighbourhood of São Cristóvão in Ouro Preto isn’t an easy place to play football.
(6) Four patients with herpes zoster ophthalmicus developed peripheral corneal ulcers with steep central edges.
(7) The results showed that measurements of impression profiles and SEM photogrammetry gave the most accurate results adjacent to regions simulating steep cavity margins, whereas the profilometric technique gave erroneous results in these regions.
(8) The intensity dependence of the early ganglion cell discharge, its latency and initial impulse frequency, is shown to follow from such a waveform, assuming that 1) latency L = l + D, where l is the time it takes for the rod response linearly summed over the ganglion cell's receptive field to reach a criterion amplitude, and D is a constant delay; and 2) the initial frequency (below saturation) is proportional to the steepness of rise of the summed rod response at time l. It is shown that the intensity dependences of 1) human visual latency and 2) brightness sensation, including effects of stimulus area and duration, are accounted for by the same model.
(9) The new protocol (standardised exponential exercise protocol, STEEP) is suitable for use on either a treadmill or a bicycle ergometer.
(10) Based on the signals observed by organ absorbance spectrophotometry from two compartments with oxidases of markedly different O2 sensitivity, the mitochondria and the peroxisomes, a distribution between high O2 and zero O2 zones is postulated, an intermediate border zone of O2 concentrations between the K0,5 (O2) values being virtually absent (steep intercellular O2 gradients).
(11) A man who had been near them reached the hotel terrace first, scrambling up a steep sandy bank.
(12) Patients with steep sloping audiograms understand better and patients with a conductive hearing loss component understand less in noisy circumstances with a hearing aid.
(13) The operational values are useful in characterising the steepness of dose-incidence curves for normal tissue injury after different fractionation schedules.
(14) Scarborough council said leaving the houses standing could cause a domino-effect down the steep slope above the picturesque harbour where the explorer Captain James Cook lodged and learned his seafaring skills.
(15) It is shown that this individual exhibits approximate alignment of her photoreceptors with the center of the retinal sphere, clear evidence of side lobes on functions, and surprisingly steep SCE I functions.
(16) For cross-linked alpha alpha, however, the curve sags at temperatures somewhat below the region of principal cooperative loss of helix, the latter occurring at higher temperature but with the same steepness as in the non-cross-linked case.
(17) A reduced venous compliance (VC) and inadequate venoconstriction may impair hemodynamics during hemodialysis, the first by impairing plasma volume preservation and by inducing a steep fall in central venous pressure (CVP) during minor plasma volume loss, the second by inadequate mobilization of hemodynamically inactive blood volume.
(18) A generally similar pattern is seen in healthy controls and in patients with untreated pulmonary tuberculosis, treated leprosy, haemophilia A and chronic obstructive lung disease (COLD) patients treated with prednisolone, but the gradient of increasing CD4:CD8 ratio with depth into the dermis is significantly less steep in patients with tuberculosis, haemophilia and prednisolone-treated COLD than in the healthy controls.
(19) Some problem drugs may be recognized if they display one or more of the following characteristics: narrow therapeutic index, steep dose-effect relationship, nonlinear kinetics, variable bioavailability, and pharmacogenetically determined kinetics.
(20) Replacement of a half of Ca++ ions by Sr++ resulted in an augmentation of steepness of the dependence on sum of [Ca++] and [Sp++], and in a more prominent fall in relaxation velocity as compared with contraction velocity.
Surface
Definition:
(n.) The exterior part of anything that has length and breadth; one of the limits that bound a solid, esp. the upper face; superficies; the outside; as, the surface of the earth; the surface of a diamond; the surface of the body.
(n.) Hence, outward or external appearance.
(n.) A magnitude that has length and breadth without thickness; superficies; as, a plane surface; a spherical surface.
(n.) That part of the side which is terminated by the flank prolonged, and the angle of the nearest bastion.
(v. t.) To give a surface to; especially, to cause to have a smooth or plain surface; to make smooth or plain.
(v. t.) To work over the surface or soil of, as ground, in hunting for gold.
Example Sentences:
(1) The resulting dose distribution is displayed using traditional 2-dimensional displays or as an isodose surface composited with underlying anatomy and the target volume.
(2) Phospholipid methylation in human EGMs is distinctly different from that in rat EGMs (Hirata and Axelrod 1980) in that the human activity is not Mg++-dependent, and apparent methyltransferase I activity is located in the external membrane surface.
(3) To quantify the size of the lesion in mice, the area of the infarct on the brain surface was assessed planimetrically 48 h after MCA occlusion by transcardial perfusion of carbon black.
(4) Using monoclonal antibodies directed against the plasma membrane of Madin-Darby canine kidney (MDCK) cells, we demonstrated previously that a glycoprotein with an Mr = 23,000 (gp23) had a non-polarized cell surface distribution and was observed on both the apical and basolateral membranes (Ojakian, G. K., Romain, R. E., and Herz, R. E. (1987) Am.
(5) In the surface epithelial cells, the basolateral cell surface showed moderate enzymatic activity.
(6) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(7) The role of Ca2+ in cell agglutination may be either to activate the cell-surface dextran receptor or to form specific intercellular Ca2+ bridges.
(8) The subcellular distribution of sialyltransferase and its product of action, sialic acid, was investigated in the undifferentiated cells of the rat intestinal crypts and compared with the pattern observed in the differentiated cells present in the surface epithelium.
(9) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
(10) A total of 555 caries lesions were registered on proximal surfaces, 49.1% being primary lesions in the enamel, 21.4% primary lesions into the dentin and 29.5% secondary lesions.
(11) Contact angles of Silafocon A and PMMA were relatively uninfluenced by front surface radii between 7.7 and 8.85 and 7.3 to 8.8 mm, respectively.
(12) These cells contained organelles characteristic of the maturation stage ameloblast and often extended to the enamel surface, suggesting a possible origin from the ameloblast layer.
(13) Together these observations suggest that cytotactin is an endogenous cell surface modulatory protein and provide a possible mechanism whereby cytotactin may contribute to pattern formation during development, regeneration, tumorigenesis, and wound healing.
(14) Our Ph1-positive ALL revealed B-cell lineage leukemia, since their surface phenotype were Ia+ and CD10+ and they have rearranged immunoglobulin JH genes.
(15) The complete nucleotide sequence of the gene for a cell surface protein antigen (SpaA) of Streptococcus sobrinus MT3791 (serotype g) was determined.
(16) To investigate the mechanism of enhanced responsiveness of cholesterol-enriched human platelets, we compared stimulation by surface-membrane-receptor (thrombin) and post-receptor (AlF4-) G-protein-directed pathways.
(17) Lysis of EAC4b,3b cellular intermediates formed to contain a low surface amount of C3b was more inhibited than was lysis of cells formed with a standard amount of C3b on the surface.
(18) After either 5 or 10 days of culture with both cytokines, intense immunofluorescent staining for Ia could be identified on the surface of greater than 80-90% of the viable islet cells.
(19) Within the capillary-perfused mucosa and muscularis (between 50 and 2000 microns from the urothelial surface), concentrations decreased by 50% for each 500-microns distance.
(20) Displacement of the surface of the cornea of bovine eyes after disruption of intact structures was investigated by means of holographic interferometry.