(v. t.) A goad; hence, something that rouses the mind or spirits; an incentive; as, the hope of gain is a powerful stimulus to labor and action.
(v. t.) That which excites or produces a temporary increase of vital action, either in the whole organism or in any of its parts; especially (Physiol.), any substance or agent capable of evoking the activity of a nerve or irritable muscle, or capable of producing an impression upon a sensory organ or more particularly upon its specific end organ.
Example Sentences:
(1) In the absence of atrial dilatation there was minimal stimulus for ANF secretion.
(2) At the same time the duodenum can be isolated from the stomach and maintained under constant stimulus by a continual infusion at regulated pressure, volume and temperature into the distal cannula.
(3) With glucose and protein as intraduodenal stimulus (no pancreatin added), the plasma amino acids rose significantly less (by approximately 50% of the control experiment) and the increment in insulin (but not C-peptide) concentrations was significantly reduced by loxiglumide.
(4) Since intracellular Ca2+ seems to play a role in stimulus-secretion coupling and ion movements, several aspects of Ca2+ homeostasis have been investigated in CF.
(5) Three coyotes were operantly conditioned to depress one of two foot treadles, left or right, depending on the condition of the stimulus light.
(6) Clinical measurements of the loudness discomfort level (LDL) are generally performed while the subject listens to a particular stimulus presented from an audiometer through headphones (AUD-HP).
(7) NE differentially affected responses to stimulus movement in the preferred and non-preferred direction in one-third of these neurons, such that directional selectivity was increased.
(8) II, the visual and auditory stimuli were exposed conversely over the habituation- (either stimulus) and the test-periods (both stimuli).
(9) The marine vibrio alone is a powerful stimulus to mucus secretion but lethal for the host.
(10) Taken together with our previous studies showing that MDMA substitutes for the phenylisopropylamine stimulant (+)amphetamine, but that neither MDE nor N-OH MDA substitute for (+)amphetamine or for the phenylisopropylamine hallucinogen 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM), the present results [i.e., MDMA-stimulus generalization to MDE, N-OH MDA, but not to (+)amphetamine] suggest that 1) MDMA produces effects other than those that may be considered amphetamine-like, and 2) MDE and N-OH MDA are MDMA-like agents with even less of an amphetamine-like component of action than MDMA itself.
(11) Changes in pain tolerance after administration of differently labelled placebos were studied by measuring the reaction time after a cold stimulus.
(12) 27% of the neurons revealed high sensitivity to the temperature stimulus with coefficient Q10 from 2.4 to 30; 6% of the neurons reacted by the on-response type; 5% of the neurons changed their activity and preserved the new level.
(13) Isolated outer hair cells from the organ of Corti of the guinea pig have been shown to change length in response to a mechanical stimulus in the form of a tone burst at a fixed frequency of 200 Hz (Canlon et al., 1988).
(14) Adhesion and O2- production were also found to be differentially affected by the NADPH oxidase inhibitor diphenylene iodonium, the sulfhydryl reagent N-ethylmaleimide and the A2 agonist adenosine, indicating that these neutrophil responses have various transductional pathways that also depend on the type of stimulus.
(15) The following results were obtained: 1) In normal subjects, the changes in ABR waveforms according to the changes of the rise-time, interstimulus interval and frequency of the stimulus were mainly attributed to component wave C. 2) In patients with central disorders, component wave C were initially affected.
(16) Following each stimulus, the subject had to press a button for RT and then report the digit perceived.
(17) Subjects with high ocular-dominance scores (right- or left-dominant subjects) showed for the green stimulus asymmetric behavior, while subjects with low ocular-dominance scores showed a tendency toward symmetry in perception.
(18) Prior to each long-term intake test, rats received a 1 min, 1 ml intraoral infusion of the same chemical stimulus.
(19) In positive patterning, elemental stimuli, A and B, were presented without an unconditioned stimulus while their compound, AB, was paired with electric shock.
(20) In a recent study, Orr and Lanzetta (1984) showed that the excitatory properties of fear facial expressions previously described (Lanzetta & Orr, 1981; Orr & Lanzetta, 1980) do not depend on associative mechanisms; even in the absence of reinforcement, fear faces intensify the emotional reaction to a previously conditioned stimulus and disrupt extinction of an acquired fear response.
Trigger
Definition:
(n.) A catch to hold the wheel of a carriage on a declivity.
(n.) A piece, as a lever, which is connected with a catch or detent as a means of releasing it; especially (Firearms), the part of a lock which is moved by the finger to release the cock and discharge the piece.
Example Sentences:
(1) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(2) PMNs could be primed for PMA-triggered oxidative burst by muramyl peptide molecules (MDP) and two of its adjuvant active nonpyrogenic derivatives.
(3) The automatic half of both the motor which advances the trepan as well as the second motor which rotates the trepan is triggered by the sudden change in electrical resistance between the trepan and the patient's internal body fluid, at the final stage of penetration.
(4) The mechanism by which gp55 causes increased erythroblastosis and ultimately leukaemia is unknown, but a reasonable suggestion is that gp55 can mimic the action of erythropoietin by binding to its receptor (Epo-R), thereby triggering prolonged proliferation of erythroid cells.
(5) Tactile stimulation of a coin-sized area in a T-2 dermatome consistently triggered a lancinating pain in the ipsilateral C-8 dermatome in a 38-year-old woman.
(6) It did the job of triggering growth, but it also fueled real-estate speculation, similar to what was going on in the mid-2000s here.” Slowing economic growth may be another concern.
(7) The findings suggest that mast cell prostaglandins are an important factor in the pathogenesis of pruritus and that local vascular responses may trigger mast cell degranulation.
(8) Among the agents triggering such an infection Chlamydia (30.9% of the cases of non-gonorrhoic urethritis), as well as mycoplasma, ureaplasma, anaerobic bacteria and herpes simplex viruses have gained particular significance.
(9) The role of surgery in triggering the reactivation of latent HSV-1, and the differences in rates of viral shedding between American and Japanese are discussed.
(10) The present results suggest that TMB-8 blocks twitches by preventing the release of Ca++ ions bound to the intracellular surface of the t-tubular membrane which is often called the store of 'trigger-calcium' ions.
(11) The figures, published in the company’s annual report , triggered immediate anger from fuel poverty campaigners who noted that energy suppliers had just been rapped over the knuckles by the Competition and Markets Authority (CMA) for overcharging .
(12) This is triggered not so much by climate change but the cause of global warming itself: the burning of fossil fuels both inside and outside the home, says Farrar.
(13) Although the Ca2+-independent mechanism accounts for about two thirds of the total acetylcholine release in the dark, the amount of acetylcholine released in this way is small compared with the release of acetylcholine triggered by stimulation of the retina with light.
(14) The results suggest an essential role of IL-6 for triggering of CD4+ T cells via the CD2 molecule.
(15) Defects in self-tolerance mechanisms could provide the genetic basis of disease or the target for environmental triggers.
(16) It is therefore suggested that salt water adaptation triggers a cellular reorganization of the epithelium in such a way that leaky junctions (a low resistance pathway) appear at the apex of the chloride cells.
(17) We report that kainic acid lesions of the posterior corpus striatum, which preferentially spare fibers of passage while destroying striatopallidal neurons, produce a stimulus-sensitive movement pattern in rats that has a highly specific sensory trigger.
(18) These results are consistent with the idea that RPE pigment dispersion is triggered by a substance that diffuses from the retina at light onset.
(19) The additional value of these methods, especially of the intensive monitoring, lies also in the possibility of compiling new knowledge about semiology and electro-clinical correlation of epileptic seizures, possible trigger mechanisms and long-term therapeutic effects.
(20) The publicity surrounding the Rotherham child exploitation scandal, which triggered the resignation of Shaun Wright, the previous PCC, did not translate into a high turnout, with only 14.65% of the electorate casting a vote.