(a.) Belonging to substance; actually existing; real; as, substantial life.
(a.) Not seeming or imaginary; not illusive; real; solid; true; veritable.
(a.) Corporeal; material; firm.
(a.) Having good substance; strong; stout; solid; firm; as, substantial cloth; a substantial fence or wall.
(a.) Possessed of goods or an estate; moderately wealthy; responsible; as, a substantial freeholder.
Example Sentences:
(1) The predicted non-Lorentzian line shapes and widths were found to be in good agreement with experimental results, indicating that the local orientational order (called "packing" by many workers) in the bilayers of small vesicles and in multilamellar membranes is substantially the same.
(2) 10D1 mAb induced a substantial proliferation of peripheral blood T cells when cross-linked with goat anti-mouse Ig antibody.
(3) Estimates of potential for gastrointestinal side effects using the rat enteropooling assay and in vivo monkey effects indicate that diarrhea will be substantially reduced with retention of uterine stimulating potency.
(4) Previous studies in this laboratory with particulate Mn3O4 have shown that preweanling rats have substantially higher tissue Mn concentrations than similarly treated adults, indicating possible differences in uptake or elimination or both.
(5) A more substantial decrease was found in Aberdeen and the larger towns near to Aberdeen than in the smaller towns further from the city.
(6) In contrast, human breast milk contained substantially increased levels of immunoreactive PTHrP.
(7) It was found that there was a substantial increase in mortality rates in the area under the jets where there was large noise radiation.
(8) But the amount of time spent above SPA has differed substantially between men and women due to women both living longer, and reaching state pension age earlier.
(9) Although statistical analysis did not show dramatic changes in all these parameters, some individual extreme values were substantially altered.
(10) Cholestyramine resin was beneficial in reducing stool bulk but had no substantial effect on fat absorption.
(11) Accordingly, LPA proved an extremely stable characteristic which did not show any substantial variations in the course of five years.
(12) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(13) Mitogen-stimulated cells always contain substantially higher levels of LDL receptor messenger RNA than corresponding resting cells.
(14) Considerable glucose 6-phosphatase activity survived 240min of treatment with phospholipase C at 5 degrees C, but in the absence of substrate or at physiological glucose 6-phosphate concentrations the delipidated enzyme was completely inactivated within 10min at 37 degrees C. However, 80mM-glucose 6-phosphate stabilized it and phospholipid dispersions substantially restored thermal stability.
(15) Amine metabolites, 5-hydroxyindoleacetic acid (5HIAA), and homovanillic acid (HVA) were not substantially affected by sleep deprivation, although there was a significant interaction of clinical response and direction of 3-methoxy-4-hydroxyphenylglycol (MHPG) change.
(16) The department of dietetics at a large teaching hospital has substantially reduced its food and labor costs through use of computerized systems that ensure efficient inventory management, recipe standardization, ingredient control, quantity and quality control, and identification of productive man-hours and appropriate staffing levels.
(17) Substantial percentages of both physicians and medical students reported access to drugs, family histories of substance abuse, stress at work and home, emotional problems, and sensation seeking.
(18) For further education, this would be my priority: a substantial increase in funding and an end to tinkering with the form of qualifications and bland repetition of the “parity of esteem” trope.
(19) The family members of depressed patients with six or more groups of DSM-III symptoms of major depression exhibited substantially higher rates of mood disorders than the family members of depressed patients with fewer than six groups of symptoms and the family members of patients with nonaffective disorders.
(20) The results presented here substantiate the hypothesis that in S. cerevisiae trehalose supplies energy during dormancy of the spores and not during the germination process.
Vast
Definition:
(superl.) Waste; desert; desolate; lonely.
(superl.) Of great extent; very spacious or large; also, huge in bulk; immense; enormous; as, the vast ocean; vast mountains; the vast empire of Russia.
(superl.) Very great in numbers, quantity, or amount; as, a vast army; a vast sum of money.
(superl.) Very great in importance; as, a subject of vast concern.
(n.) A waste region; boundless space; immensity.
Example Sentences:
(1) It is a place that occupies two thirds of our planet but very little is known of vast swaths of it.
(2) In this phase the educational practices are vastly determined by individual activities which form the basis for later regulations by the state.
(3) The effects of brain injury can be catastrophic and long-term so the impact of more research would be vast, but affected numbers are too small so it loses out.
(4) Does anybody honestly believe the vast majority of migrants don’t want that too?
(5) The vast majority of small cells were probably displaced amacrine cells.
(6) I never had any doubt that the vast majority of people engaged in "business" are not the exploiters but the exploited.
(7) In response, detainees – the vast majority of them failed asylum seekers who have committed no crime – waved and shared messages of solidarity.
(8) Not because we are “chippy, moronic gits” (thank you, Twitter), but because we do not see the social benefit of a two-tier education system that provides a small minority with vastly more opportunities than the rest.
(9) It is important to pay attention to the outcome of this study in (postgraduate) education for general practitioners, as they treat the vast majority of urethritis patients.
(10) The drugs used in early studies - diuretics, vasodilators and reserpine - greatly improved mortality from malignant hypertension, apoplectic stroke and congestive heart failure, but had little or no effect in persons with milder degrees of elevated blood pressure, who constitute the vast majority of hypertensives.
(11) We report that specific human (dC-dA)n.(dG-dT)n blocks are polymorphic in length among individuals and therefore represent a vast new pool of potential genetic markers.
(12) The discovery of this vast tranche of documents has prompted historians to suggest that a major reappraisal of the end of Britain's empire will be required once these materials have been digested – a "hidden history" if ever there were one.
(13) The vast majority of the epithelial cells were secretory, and the rest were ciliated.
(14) Even the landscape is secretive: vast tracts of crown land and hidden valleys with nothing but a dead end road and lonely farmhouse, with a tractor and trailer pulled across the farmyard for protection.
(15) Lethal pulmonary embolism is associated with hypoxemia and hypocapnia in the vast majority of cases.
(16) The vast majority of members would rather have a quiet body, offering technical assistance here and there and convening an occasional summit.
(17) Europe was never going to be another America or Soviet Union, with one constitution imposing national homogeneity over vast distances, and with people and investment migrating ceaselessly in search of employment.
(18) In the southern state of Karnataka, corruption is blamed for uncontrolled mining in vast areas of protected forest.
(19) Mali: a guide to the conflict Read more In response, the Tuareg separatists attacked military and police points as far as Tenenkou in the south, to prove it still controlled vast swaths of the desert territory.
(20) The vast majority of the subjects had correctly been given the diagnosis of cerebrovascular disease.