(1) The fine structure of neurofibrillary tangles in the hippocampal gyrus, substantia nigra, pontine nuclei and locus coeruleus of the brain was postmortem studied in a case of progressive supranuclear palsy.
(2) It was the ease with which minor debt could slide into a tangle of hunger and despair.
(3) Although a trend was observed for TMA-DPH mobility to parallel histopathologic severity in hippocampal specimens, the biophysical changes did not appear to reflect a loss of neuronal membranes relative to glial membranes or the presence of senile plaques or neurofibrillary tangles.
(4) Neurofibrillary tangles (NFT), one of the pathological hallmarks of Alzheimer's disease are observed in very high densities in the brains of former professional boxers suffering from dementia pugilistica.
(5) Elevated brain Al concentrations, especially in cortical regions, were associated with behavioral changes and the development of neurofibrillary tangles (NFTs).
(6) The smoky density of the mackerel was nicely offset by the pointed black olive tapenade and the fresh, zingy flavours present in little tangles of tomato, shallot, red pepper and spring onion, a layer of pea shoots and red chard, and the generous dressing of grassy olive oil.
(7) Changes were more severe in white matter close to cortical areas with a great density of neurofibrillary tangles.
(8) There is a tangled web between Salazar, Nike, Farah and the Nike Oregon Project on one hand, and the British Athletics performance director, Neil Black, and head of endurance, Barry Fudge, on the other.
(9) Whereas cortical senile plaque count did not distinguish well between demented and nondemented subjects, every subject with numerous cortical neurofibrillary tangles was demented.
(10) Clinical symptoms of amnesia appear when amyloid induces neighbouring neuritic alterations: paired helical filaments and distant neuronal body lesions: neurofibrillary tangles.
(11) Staggerer cerebellar cortex exhibits the greatest fluorescence with most terminals appearing as matted tangles adjacent cell bodies.
(12) Tangle-free neurons in both diseased and control brains showed weak to absent intracytoplasmic immunoreactivity.
(13) But tangled up in its visions of thousands of new “starter homes” – 5,000 more of which were promised on Monday, when the government said it was going to directly commission housebuilding on five sites in the south of England – are an array of drastic measures aimed at what remains of England’s council homes.
(14) The capacity for protein synthesis in tangled cells appears, therefore, to be progressively decreased with accumulation of tangle, whereas that for oxidative metabolism is maintained and lysosomal activity, perhaps, increased.
(15) On electron microscopy the normal lamellar pattern made up of orientated collagen fibrils all about 80 nm diameter is replaced by a random tangled pattern of much thinner irregularly curved fibrils, some as thin as 5nm.
(16) Eight brains failed to reveal considerable numbers of neuritic plaques, neurofibrillary tangles, and neuropil threads, but these brains showed the presence of abnormal and intensely argyrophilic grains loosely scattered throughout the neuropil.
(17) N-Terminal and C-terminal domains of tau were found to be present in tangles in situ.
(18) The neuropathological lesions were assessed using a fluorescent stain for neuritic plaques and neurofibrillary tangles.
(19) However, increased knowledge concerning macromolecular abnormalities in amyloid containing plaques and neurofibrillary tangles makes the outlook for a diagnostic test for AD on CSF promising.
(20) The trial, originally expected to be staid, has exposed severe dysfunction within Bo's family and detailed the complicated tangle of allegiances and affairs that led to his downfall .
Twisted
Definition:
(imp. & p. p.) of Twist
(a.) Contorted; crooked spirally; subjected to torsion; hence, perverted.
Example Sentences:
(1) Aberrant forms (elongated and twisted) in the vacuole and double virions in the plasma membrane were observed as early as 65 h after infection.
(2) Electron microscopy shows that at neutral pH, CEA particles consist of homogeneous, morphologically distinctive, twisted rod-shaped particles, about 9 X 40 nm.
(3) Rapid swelling of the knee following a blow or twisting injury is considered a significant injury.
(4) Intermolecular contacts occur in both oligomers in the minor groove: in the B form through twisted guanine-guanine hydrogen bonding, and in the Z form through base-base stacking and the water network.
(5) Ings twisted the knee during his first training session with Klopp in charge and tests have shown the former Burnley forward ruptured an anterior cruciate ligament, meaning that a player who has just broken into England’s senior team will be out for a minimum of six months.
(6) Leicester looked a little sorry for themselves and, with their concentration down, United twisted the knife.
(7) Gowher Rizvi, chief representative of the prime minister, Sheik Hasina, told the Guardian that preparations for the forthcoming elections, were "completely on track" and that the tribunal, probing crimes committed during the 1971 war in which Bangladesh broke away from Pakistan, was about bringing justice previously denied by "the twists and turns" of the country's history.
(8) The base orientations are characterized by a substantial inclination and propellor twist.
(9) Among the non-standard postures examined were: twisting while lifting or lowering, lifting and lowering from lying, sitting, kneeling, and squatting positions, and carrying loads under conditions of constricted ceiling heights.
(10) A vicious feud playing out within Uzbekistan's ruling family took a new twist on Monday , when prosecutors announced that the clan's most flamboyant member faces charges of involvement in mafia-style corruption.
(11) The possible arrangements of molecules within the twisted ribbons have been deduced and are found to be fairly closely related.
(12) Idiopathic torsion dystonia (ITD) is characterized by sustained, involuntary muscle contractions, frequently causing twisting and repetitive movements or abnormal postures.
(13) These results indicate that the polypeptide chain, driven by energetics (nonbonded and electrostatic interactions), is folded into a typical left-handed twisted four-helix bundle with an approximately 4-fold symmetric array, as observed in most four alpha-helix proteins.
(14) In the mutants twist and snail, which fail to differentiate the ventrally derived mesoderm, mitoses specific to the mesoderm are absent.
(15) Fulham were helped by United being forced into a trio of substitutions at the interval, as Rafael succumbed to a twisted ankle, Cleverly had double vision and Evans had back trouble.
(16) Blockage of the balloon system was possibly caused by twisting the system to reach and pass the lesion in the branch of left circumflex coronary artery.
(17) In the tradition of the American author Patricia Highsmith, creator of the charming psychopath Tom Ripley, Rendell used twisting plots to expose twisted minds.
(18) From previous genetic and biochemical studies it was hypothesized that dorsal might be responsible for the activation of the zygotic gene twist.
(19) Finally, the twisted nose was treated by freeing the nasal components, straightening the bone and cartilage, and replacing them in their anatomical positions.
(20) It doesn’t do a lot at the moment, but there’s a lot of potential for a modern twist on board games here.