(n.) A catch to hold the wheel of a carriage on a declivity.
(n.) A piece, as a lever, which is connected with a catch or detent as a means of releasing it; especially (Firearms), the part of a lock which is moved by the finger to release the cock and discharge the piece.
Example Sentences:
(1) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(2) PMNs could be primed for PMA-triggered oxidative burst by muramyl peptide molecules (MDP) and two of its adjuvant active nonpyrogenic derivatives.
(3) The automatic half of both the motor which advances the trepan as well as the second motor which rotates the trepan is triggered by the sudden change in electrical resistance between the trepan and the patient's internal body fluid, at the final stage of penetration.
(4) The mechanism by which gp55 causes increased erythroblastosis and ultimately leukaemia is unknown, but a reasonable suggestion is that gp55 can mimic the action of erythropoietin by binding to its receptor (Epo-R), thereby triggering prolonged proliferation of erythroid cells.
(5) Tactile stimulation of a coin-sized area in a T-2 dermatome consistently triggered a lancinating pain in the ipsilateral C-8 dermatome in a 38-year-old woman.
(6) It did the job of triggering growth, but it also fueled real-estate speculation, similar to what was going on in the mid-2000s here.” Slowing economic growth may be another concern.
(7) The findings suggest that mast cell prostaglandins are an important factor in the pathogenesis of pruritus and that local vascular responses may trigger mast cell degranulation.
(8) Among the agents triggering such an infection Chlamydia (30.9% of the cases of non-gonorrhoic urethritis), as well as mycoplasma, ureaplasma, anaerobic bacteria and herpes simplex viruses have gained particular significance.
(9) The role of surgery in triggering the reactivation of latent HSV-1, and the differences in rates of viral shedding between American and Japanese are discussed.
(10) The present results suggest that TMB-8 blocks twitches by preventing the release of Ca++ ions bound to the intracellular surface of the t-tubular membrane which is often called the store of 'trigger-calcium' ions.
(11) The figures, published in the company’s annual report , triggered immediate anger from fuel poverty campaigners who noted that energy suppliers had just been rapped over the knuckles by the Competition and Markets Authority (CMA) for overcharging .
(12) This is triggered not so much by climate change but the cause of global warming itself: the burning of fossil fuels both inside and outside the home, says Farrar.
(13) Although the Ca2+-independent mechanism accounts for about two thirds of the total acetylcholine release in the dark, the amount of acetylcholine released in this way is small compared with the release of acetylcholine triggered by stimulation of the retina with light.
(14) The results suggest an essential role of IL-6 for triggering of CD4+ T cells via the CD2 molecule.
(15) Defects in self-tolerance mechanisms could provide the genetic basis of disease or the target for environmental triggers.
(16) It is therefore suggested that salt water adaptation triggers a cellular reorganization of the epithelium in such a way that leaky junctions (a low resistance pathway) appear at the apex of the chloride cells.
(17) We report that kainic acid lesions of the posterior corpus striatum, which preferentially spare fibers of passage while destroying striatopallidal neurons, produce a stimulus-sensitive movement pattern in rats that has a highly specific sensory trigger.
(18) These results are consistent with the idea that RPE pigment dispersion is triggered by a substance that diffuses from the retina at light onset.
(19) The additional value of these methods, especially of the intensive monitoring, lies also in the possibility of compiling new knowledge about semiology and electro-clinical correlation of epileptic seizures, possible trigger mechanisms and long-term therapeutic effects.
(20) The publicity surrounding the Rotherham child exploitation scandal, which triggered the resignation of Shaun Wright, the previous PCC, did not translate into a high turnout, with only 14.65% of the electorate casting a vote.
Wheel
Definition:
(n.) A circular frame turning about an axis; a rotating disk, whether solid, or a frame composed of an outer rim, spokes or radii, and a central hub or nave, in which is inserted the axle, -- used for supporting and conveying vehicles, in machinery, and for various purposes; as, the wheel of a wagon, of a locomotive, of a mill, of a watch, etc.
(n.) Any instrument having the form of, or chiefly consisting of, a wheel.
(n.) A spinning wheel. See under Spinning.
(n.) An instrument of torture formerly used.
(n.) A circular frame having handles on the periphery, and an axle which is so connected with the tiller as to form a means of controlling the rudder for the purpose of steering.
(n.) A potter's wheel. See under Potter.
(n.) A firework which, while burning, is caused to revolve on an axis by the reaction of the escaping gases.
(n.) The burden or refrain of a song.
(n.) A bicycle or a tricycle; a velocipede.
(n.) A rolling or revolving body; anything of a circular form; a disk; an orb.
(n.) A turn revolution; rotation; compass.
(v. t.) To convey on wheels, or in a wheeled vehicle; as, to wheel a load of hay or wood.
(v. t.) To put into a rotatory motion; to cause to turn or revolve; to cause to gyrate; to make or perform in a circle.
(v. i.) To turn on an axis, or as on an axis; to revolve; to more about; to rotate; to gyrate.
(v. i.) To change direction, as if revolving upon an axis or pivot; to turn; as, the troops wheeled to the right.
(v. i.) To go round in a circuit; to fetch a compass.
(v. i.) To roll forward.
Example Sentences:
(1) By the 1860s, French designs were using larger front wheels and steel frames, which although lighter were more rigid, leading to its nickname of “boneshaker”.
(2) From the standpoint of breakeven facts and resource efficiency the minicenter and clinic-on-wheels were similar and superior to the other two.
(3) Among the improved patients, eight became ambulatory and independent in activities of daily living (ADL), eight became independent from a wheel-chair level, and eight returned home or to the community.
(4) This is where he would infuriate the neighbours by kicking the football over his house into their garden; this is Old Street, where his friends would wait in their car to whisk him off to basketball without his parents knowing; Pragel Street, where physiotherapists spotted him being wheeled in a Tesco shopping trolley by friends and suggested he took up basketball; the Housing Options Centre, where he sent a letter forged in his father's name saying he had thrown 16-year-old Ade out and he needed social housing.
(5) The chicks were individually placed in running wheels for 2 x 1 hr, 24 hr before testing.
(6) A total of 60 male Sprague-Dawley rats were randomly assigned at 6 weeks of age to a sedentary control group (n = 22) or to a group with unlimited access to a running wheel (n = 38).
(7) The relatively conservative behavior of these mice in selecting between multiple sources of food and water and different types of activity wheels suggests the need for careful experimental design in free-choice studies with inexperienced animals.
(8) Of course, if the wheels are falling off the regime, people will try to find a way out, but it is much more likely that they will simply defect, rather than try to pull off a coup and then negotiate a deal for the regime.
(9) The pressure sore resulted from the commonly practised habit of grasping the upright of the wheel chair with the upper arm in order to gain stability.
(10) Blinded female reats were placed in running-wheel cages to monitor the phase of their activity cycle.
(11) Cells have been injected iontophoretically with the calcium sensitive metallochromic dye arsenazo III and changes in differential absorbance have been measured using a spinning wheel microspectrophotometer.
(12) Motor vehicle occupants may suffer severe cervical airway injuries as the result of impaction with the steering wheel, dashboard, windshield, backseat, and seat belt.
(13) The 2008 financial crisis saw countries adopt extreme measures to keep the economic wheels turning, for example by reducing interest rates to record lows , pumping billions into the system through quantitative easing in the US, Japan, the UK and the euro-area, and striking trade deals to open markets further.
(14) The causes of barotrauma were: 1) Undue length of the tube pressed by machine's wheel which connect the ventilator to the anesthesia machine.
(15) The role of steering wheel design in maxillofacial trauma is discussed and new solutions briefly reviewed.
(16) For US allies, trying to follow Washington’s lead over the past four months has been akin to trying to drive in convoy behind a car swerving violently at high speed, as the competing factions inside lunge for the steering wheel.
(17) Last month, neighbours watched in silence as her bloodstained body was wheeled out of the front door of the small house she shared with her two daughters on the outskirts of the Honduran capital of Tegucigalpa.
(18) This tends to push buyers behind the wheel of a diesel, which usually produces less CO2 than an equivalent petrol.
(19) Towards the end, as entire eras wheeled past in a blur, I realised the programme itself would outlive me, and began desperately scrawling notes that described the broadcast's initial few centuries for the benefit of any descendants hoping to pick up from where I left off.
(20) But it also succeeded by elevating the likes of Luke Skywalker and Han Solo to the kind of status usually reserved for totemic superheroes such as Batman, Superman and Spider-Man, characters destined to be wheeled out time and time again in different big screen iterations.