(a.) To lower or depress; to throw or cast down; as, to abase the eye.
(a.) To cast down or reduce low or lower, as in rank, office, condition in life, or estimation of worthiness; to depress; to humble; to degrade.
Example Sentences:
(1) And then, proving that in the celebrity world of self-abasement there really is no such thing as "bottoming out", Shane started tweeting Ping Pong, otherwise known as Elizabeth Hurley's parrot Why has Australia not staged an intervention?
(2) These studies establish that the exocyclic ring of the 1,N2-propanodeoxyguanosine adduct fits into the cavity generated by the abasic site.
(3) Covalently closed circular DNA containing a synthetic analog of an abasic site at a unique position was used as a substrate to study DNA repair.
(4) In this study, we present structural and dynamic properties of duplex oligodeoxynucleotides containing G, C and T opposite a model abasic site studied by one and two-dimensional nuclear magnetic resonance spectroscopy.
(5) By this assay, we first identified the formation of C-4'-hydroxy abasic sites in calf thymus DNA by neocarzinostatin.
(6) Abasic lesions in the template had relatively little effect on the polymerase incorporation reaction at sites proximal to the lesion.
(7) Facebook Twitter Pinterest A composite handout of CCTV pictures from the Metropolitan police showing British teenagers (L-R) Kadiza Sultana, Amira Abase and Shamima Begum passing through security barriers at Gatwick Airport en route to Syria.
(8) Proton and phosphorus NMR studies are reported for two complementary nonanucleotide duplexes containing acyclic abasic sites.
(9) Shamima Begum, 15, Amira Abase, 15, and Kadiza Sultana, 16, left their homes in east London last month to join the extremist group.
(10) However, incorporation opposite an abasic site was undetectable relative to that which occurred opposite a normal template nucleotide.
(11) But with the People's Daily writing that progress had only been possible because of David Cameron's admission that he had mishandled Tibet (where, since 2009, 100 monks and nuns have set fire to themselves in protest against Chinese rule), Britain's abasement was complete.
(12) Shamima Begum, 15, Kadiza Sultana, 16, and Amira Abase, 15, fled in February from Britain after deceiving their parents and siblings.
(13) The long pilgrimage of pregnancy with its wonders and abasements, the apotheosis of childbirth, the sacking and slow rebuilding of every last corner of my private world that motherhood has entailed – all unmentioned, wilfully or casually forgotten as time has passed.
(14) Before and after training they were low in need for order, endurance, abasement, and deference and high in need for autonomy and aggression.
(15) All the sequenced mutants correspond to single base-pair substitutions targeted at the abasic site.
(16) These results indicate that dTMP, and not dAMP, was mainly incorporated into the sites opposite to the abasic site analogue, and that incorrect deoxynucleotides were incorporated in the position adjacent to the abasic site analogue.
(17) Our results in human cells contrast markedly with those published previously for the mutational specificity of AP sites in Escherichia coli, in which a large majority of the mutants resulted from insertion of an A opposite the abasic site.
(18) The repair-related DNA synthesis was localized within 3 or 4 nucleotides surrounding the abasic site.
(19) The enzyme is able to incorporate nucleotides efficiently opposite the abasic template lesion and to continue DNA synthesis.
(20) The Met statement did appear to show some contrition stating: “With the benefit of hindsight, we acknowledge that the letters could have been delivered direct to the parents.” The disappearance of the 15-year-old girl in December led to a counter-terrorism investigation that saw Begum, Sultana and Abase identified as friends of the missing girl and being spoken to by detectives.
Base
Definition:
(a.) Of little, or less than the usual, height; of low growth; as, base shrubs.
(a.) Low in place or position.
(a.) Of humble birth; or low degree; lowly; mean.
(a.) Illegitimate by birth; bastard.
(a.) Of little comparative value, as metal inferior to gold and silver, the precious metals.
(a.) Alloyed with inferior metal; debased; as, base coin; base bullion.
(a.) Morally low. Hence: Low-minded; unworthy; without dignity of sentiment; ignoble; mean; illiberal; menial; as, a base fellow; base motives; base occupations.
(a.) Not classical or correct.
(a.) Deep or grave in sound; as, the base tone of a violin.
(a.) Not held by honorable service; as, a base estate, one held by services not honorable; held by villenage. Such a tenure is called base, or low, and the tenant, a base tenant.
(n.) The bottom of anything, considered as its support, or that on which something rests for support; the foundation; as, the base of a statue.
(n.) Fig.: The fundamental or essential part of a thing; the essential principle; a groundwork.
(n.) The lower part of a wall, pier, or column, when treated as a separate feature, usually in projection, or especially ornamented.
(n.) The lower part of a complete architectural design, as of a monument; also, the lower part of any elaborate piece of furniture or decoration.
(n.) That extremity of a leaf, fruit, etc., at which it is attached to its support.
(n.) The positive, or non-acid component of a salt; a substance which, combined with an acid, neutralizes the latter and forms a salt; -- applied also to the hydroxides of the positive elements or radicals, and to certain organic bodies resembling them in their property of forming salts with acids.
(n.) The chief ingredient in a compound.
(n.) A substance used as a mordant.
(n.) The exterior side of the polygon, or that imaginary line which connects the salient angles of two adjacent bastions.
(n.) The line or surface constituting that part of a figure on which it is supposed to stand.
(n.) The number from which a mathematical table is constructed; as, the base of a system of logarithms.
(n.) A low, or deep, sound. (Mus.) (a) The lowest part; the deepest male voice. (b) One who sings, or the instrument which plays, base.
(n.) A place or tract of country, protected by fortifications, or by natural advantages, from which the operations of an army proceed, forward movements are made, supplies are furnished, etc.
(n.) The smallest kind of cannon.
(n.) That part of an organ by which it is attached to another more central organ.
(n.) The basal plane of a crystal.
(n.) The ground mass of a rock, especially if not distinctly crystalline.
(n.) The lower part of the field. See Escutcheon.
(n.) The housing of a horse.
(n.) A kind of skirt ( often of velvet or brocade, but sometimes of mailed armor) which hung from the middle to about the knees, or lower.
(n.) The lower part of a robe or petticoat.
(n.) An apron.
(n.) The point or line from which a start is made; a starting place or a goal in various games.
(n.) A line in a survey which, being accurately determined in length and position, serves as the origin from which to compute the distances and positions of any points or objects connected with it by a system of triangles.
(n.) A rustic play; -- called also prisoner's base, prison base, or bars.
(n.) Any one of the four bounds which mark the circuit of the infield.
(n.) To put on a base or basis; to lay the foundation of; to found, as an argument or conclusion; -- used with on or upon.
(a.) To abase; to let, or cast, down; to lower.
(a.) To reduce the value of; to debase.
Example Sentences:
(1) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
(2) However, CT will be insensitive in the detection of the more cephalic proximal lesions, especially those in the brain stem, basal cisterns, and skull base.
(3) Recently, the validity of the American Thoracic Society (ATS) standards for selection of spirometric test results has been questioned based on the finding of inverse dependence of FEV1 on effort.
(4) The omission of Crossrail 2 from the Conservative manifesto , in which other infrastructure projects were listed, was the clearest sign yet that there is little appetite in a Theresa May government for another London-based scheme.
(5) Squadron Leader Kevin Harris, commander of the Merlins at Camp Bastion, the main British base in Helmand, praised the crews, adding: "The Merlins will undergo an extensive programme of maintenance and cleaning before being packed up, ensuring they return to the UK in good order."
(6) The analysis is based on the personal experience of the authors with 117 cases and the review of 223 cases published in the literature.
(7) In the fall of 1975, 1,915 children in grades K through eight began a school-based program of supervised weekly rinsing with 0.2 percent aqueous solution of sodium fluoride in an unfluoridated community in the Finger Lakes area of upstate New York.
(8) Basing the prediction of student performance in medical school on intellective-cognitive abilities alone has proved to be more pertinent to academic achievement than to clinical practice.
(9) Induction of labor, based upon only (1) a finding of meconium in the amniocentesis group or (2) a positive test in the OCT group, was nearly three times more frequent in the amniocentesis group.
(10) Therefore, we have developed a powerful new microcomputer-based system which permits detailed investigations and evaluation of 3-D and 4-D (dynamic 3-D) biomedical images.
(11) The distance between the end of fic and the start of pabA was 31 base pairs.
(12) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(13) The method is based on two-dimensional scanning photon absorptiometry on the distal part of the forearm.
(14) At the fepB operator, a 31 base-pair Fur-protected region was identified, corresponding to positions -19 to +12 with respect to the transcriptional start site.
(15) Facebook Twitter Pinterest With a plot based around fake (or real?)
(16) Based on our results, we propose the following hypotheses for the neurochemical mechanisms of motion sickness: (1) the histaminergic neuron system is involved in the signs and symptoms of motion sickness, including vomiting; (2) the acetylcholinergic neuron system is involved in the processes of habituation to motion sickness, including neural store mechanisms; and (3) the catecholaminergic neuron system in the brain stem is not related to the development of motion sickness.
(17) Based on these results, we concluded that the inhibition of putrefactive anaerobe 3679 by sorbate resulted from a stringent-type regulatory response induced by the protonophoric activity of sorbic acid.
(18) Thus, mechanical restitution of the ventricle is a dynamic process that can be assessed using an elastance-based approach in the in situ heart.
(19) Mapping of the cross-link position between U2 and U6 RNAs is consistent with base-pairing between the 5' domain of U2 and the 3' end of U6 RNA.
(20) Descriptive features of the syndrome in children, adults and adolescents are given based on the respective work of Pine, Masterson and Kernberg.