(n.) Doing; trouble; difficulty; troublesome business; fuss; bustle; as, to make a great ado about trifles.
Example Sentences:
(1) This inhibition was correlated with the enhanced Ado toxicity, suggesting inhibition of methylation as a possible causal factor for the great increase in Ado sensitivity.
(2) S-Adenosyl-L-methionine (Ado-met) administration to rats significantly improved liver necrosis induced by thioacetamide (TAA) as evidenced by reduction of TAA-elevated catalytic activity of serum aspartate aminotransferase (AST) and alanine aminotransferase (ALAT).
(3) Apparent Michaelis (Km) constants for the two cosubstrates for the reaction, 6-MP and S-adenosyl-L-methionine (Ado-Met), in mouse kidney were 7.0 X 10(-4) M and 2.4 X 10(-6) M respectively.
(4) Since ADO is a metabolic substrate and a nonselective receptor agonist, while CHA is A1-selective and a poor substrate for cellular uptake, neither A2 activation nor cellular uptake altered expression of the A1 effect of exogenous ADO.
(5) Both 20 microM nitrobenzylthioinosine (NBMPR), an inhibitor of the purine nucleoside carrier, and 0.1 mM alpha,beta-methylene adenosine diphosphate (AOPCP), an inhibitor of 5'-nucleotidase activity, attenuate DNP-stimulated ADO release (NBMPR by 62% and ADOCP by 76%).
(6) The effect of adenosine (ADO) on the recovery of cellular adenine nucleotides (AN) was evaluated in the cultured cells deprived of oxygen and substrates (ischemia) and in nonischemic cells (control).
(7) The brain dialysis technique was used to (a) deliver drugs locally to brain tissue, (b) estimate cerebral ISF ADO levels, and (c) measure local CBF (hydrogen clearance).
(8) The present experiments were designed to examine the effects of Ado and adenosine analogues on net chloride (JCl) and bicarbonate (JHCO3) absorption by the isolated, perfused MTAL of the rat.
(9) In other tissues, such as adipose and skeletal muscle, much attention has focused on the role of ADO as a metabolic regulator of the actions of insulin.
(10) Adenosine (ADO) in low micromolar levels and hypoxanthine (HYP) in millimolar levels have been shown to inhibit maturation of cumulus-enclosed oocytes.
(11) Mitogenic stimulation of B cell DNA synthesis was antagonized by 2Cl Ado while adenosine produced both stimulations and inhibitions.
(12) These results suggest that the beta-adrenergic stimulation the interstitial level of ADO in the heart increases to levels that are sufficient to manifest its antiadrenergic effects.
(13) In an experiment with tRNAPhe which is a substrate for a single, namely m5C methylase, the type of inhibition of this methylase by S-Cyd-Hcy was revealed; it was found to be non-competitive with respect to S-Ado-Met, and the S-Cyd-Hcy concentration reducing the methylation by 50 percent was 1.2-10(-4) M.
(14) He also appeared in a number of Branagh's films including Much Ado About Nothing (1993) and as Polonius in Hamlet (1996).
(15) These results provide indirect evidence that in enterocytes methylmalonyl-CoA mutase, the coenzyme of which is Ado-Cbl, is located in the mitochondrial fraction and that methionine synthetase, the coenzyme of which is Me-Cbl, is located in the sap fraction.
(16) Now Michael, what was the word I just said?” I told her the word was “Monday” and, with no more ado, she returned to her desk and clattered something out on her computer.
(17) Nevertheless, the antiviral action of F-C-Ado appears to be targeted at AdoHcy hydrolase.
(18) Low (nM) amounts of the Ado agonists inhibited cAMP formation in both cell types.
(19) This was confirmed by the comparison of the rates of hydrolysis of m7Guo5'PPP5'Ado by the enzyme in the presence of various nucleotides.
(20) He owed his late-flourishing film career to Branagh, appearing in a string of his movies: as Bardolph in Henry V (1989), Leonato in Much Ado About Nothing (1993), the old blind man in Mary Shelley's Frankenstein (1994), a cantankerous old thespian in A Midwinter's Tale (1995), Polonius in Hamlet (1996) and Sir Nathaniel in the musical Love's Labour's Lost (2000).
Agreement
Definition:
(n.) State of agreeing; harmony of opinion, statement, action, or character; concurrence; concord; conformity; as, a good agreement subsists among the members of the council.
(n.) Concord or correspondence of one word with another in gender, number, case, or person.
(n.) A concurrence in an engagement that something shall be done or omitted; an exchange of promises; mutual understanding, arrangement, or stipulation; a contract.
(n.) The language, oral or written, embodying reciprocal promises.
Example Sentences:
(1) The predicted non-Lorentzian line shapes and widths were found to be in good agreement with experimental results, indicating that the local orientational order (called "packing" by many workers) in the bilayers of small vesicles and in multilamellar membranes is substantially the same.
(2) The highest rate of discontinuation occurred when method choice was denied in the presence of husband-wife agreement on method choice, and the lowest rate occurred when method choice was granted in the presence of such concurrence.
(3) At the heart of the payday loan profit bonanza is the "continuous payment authority" (CPA) agreement, which allows lenders to access customer bank accounts to retrieve funds.
(4) Interadjudicator agreement was stronger on 'originality' than on 'aesthetic pleasingness'.
(5) The prospectus revealed he has an agreement with Dorsey to vote his shares, which expires when the company goes public in November.
(6) Reasonably good agreement is seen between theoretical apparent rate-vesicle concentration relationships and those measured experimentally.
(7) The data for the eubacterial ribosomes are in full agreement with the model of the 50S protein topography derived from immunological data.
(8) Cytochemical studies on renal peroxisomes were in agreement with these biochemical findings.
(9) Amid the acrimony of the failed debate on the Malaysia Agreement, something was missed or forgotten: many in the left had changed their mind.
(10) The White House denied there had been an agreement, but said it was open in principle to such negotations.
(11) Couples in need of help will be "encouraged" to come to a private agreement.
(12) In agreement with the data in the literature, melanocytes incubated with IFN-gamma acquire HLA-DR, -DQ, and -DP antigens.
(13) These calculated values are compared with observed values and implications of the agreement are discussed.
(14) In 0.17 M Na+(aq), tRNA(Phe) exists in its native conformation and the number of strong binding sites (Ka greater than or equal to 10(4)) was estimated to be 3-4 by titration experiments, in agreement with X-ray structural data for crystalline tRNA(Phe) (Jack et al., 1977).
(15) These data were in agreement with those from a previous comparative study which had a very different research design and a somewhat different type of schizophrenic population.
(16) There was good agreement between the survival of normally oxygenated cells in culture and bright cells from tumors and between hypoxic cells in culture and dim cells from tumors over a radiation dosage range of 2-5 Gray.
(17) Herman Van Rompuy, the European Council president chairing the summit, hoped to finesse an overall agreement on the banking supervisor.
(18) Time-resolved tyrosine fluorescence anisotropy shows global correlation times broadly in agreement with the NMR results, but with an additional faster correlation time [approximately 600 ps].
(19) Off The Hook has facilities of up to £30,000 from the bank, a signatory to the Project Merlin agreement.
(20) Analysts say Zuma's lawyers may try to reach agreement with the prosecutors, while he can also appeal against yesterday's ruling before the constitutional court.