(v. t.) To render larger, more extended, or more intense, and the like; -- used especially of telescopes, microscopes, etc.
(v. t.) To enlarge by addition or discussion; to treat copiously by adding particulars, illustrations, etc.; to expand; to make much of.
(v. i.) To become larger.
(v. i.) To speak largely or copiously; to be diffuse in argument or description; to dilate; to expatiate; -- often with on or upon.
Example Sentences:
(1) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(2) We have investigated the increase in the spcDNA population upon cycloheximide treatment of individual sequences, which are found to amplify differentially.
(3) We conclude that only one of the alleles was amplified and that either allele could be amplified with respect to both the SphI and PvuII polymorphisms.
(4) RNA preparations were reverse-transcribed, amplified by a polymerase chain reaction (PCR), and separated by electrophoresis.
(5) It was previously demonstrated that multidrug-resistant Chinese hamster cell lines contain an amplified, transcriptionally active DNA sequence designated mdr.
(6) Chloroquine increased the binding of 125I-labeled insulin to rat hepatoma cells (R-Y121B) at 4 degrees C. The effect of chloroquine on insulin binding was amplified at 23 degrees C, and a large increase in cell-associated radioactivity was observed.
(7) Overexpression of asparagine synthetase in beta-aspartyl hydroxamate-resistant lines without amplified copies of the gene was also correlated with DNA hypomethylation.
(8) (iii) The insertion plasmid pRSD102(R388::Tn1721) has conserved the capacity of the original plasmid pRSD1 to amplify the 3.55 Mdal-tet region.
(9) To identify the molecular defect in a patient with the intermediate form of the disease, arylsulfatase B mRNA from his fibroblasts was reverse-transcribed, amplified by the polymerase chain reaction, and subcloned.
(10) In addition to the fatigue tester and the pulse duplicator, a signal conditioner, a DC amplifier, an analog-to-digital converter, and a digital microcomputer comprised the essential hardware.
(11) The sensitivity of a PCR system to amplify the long terminal repeat (LTR) sequence of HIV-1 was not affected by the irradiation procedure; however, the ultimate sensitivity of a PCR system for the amplification of an early gene promotor sequence of the CMV genome was reduced 1000-fold.
(12) Thus MTX combined with PALA selected cells with an 'amplificator' phenotype (an increased ability to amplify parts of the genome).
(13) HDV cDNA was then directly amplified with Taq polymerase using three pairs of specific primers.
(14) As an extension to the variety of existing techniques using polymorphic DNA markers, the Random Amplified Polymorphic DNA (RAPD) technique may be used in molecular ecology to determine taxonomic identity, assess kinship relationships, analyse mixed genome samples, and create specific probes.
(15) cDNA was prepared by reverse transcription of peripheral blood mRNA and amplified by the polymerase chain reaction (PCR) using primers corresponding to sequences 400 bp apart on the cDNA, spanning the last three exons (X, Y, Z) of the beta-Sp gene.
(16) Whether we would use that to support and amplify the community ideals already present or go the way of gentrification remained to be seen.
(17) Optimum specific amplification resulted when the primer annealing temperature was 60 degrees C. The gene fragment was amplifiable in 25 different Brucella species and strains.
(18) The action of exogenous etiologic agents is usually mediated in part or amplified by endogenous mediators that very often exert biphasic, i.e., damaging and protective, effects.
(19) By using primer 1 (5'-AAAGAATTCATGGAATCCAGGATCTG-3', upstream nucleotides 157 to 2877), primer 2 (5'-AAAGAATTCATGAACGTGAAGGAATCG-3', upstream nucleotides 1846 to 2877), and primer 4(5'-ATAAAGCTTAATCAGACGTTCTCTTCTTC-3', downstream nucleotides 157 to 2877 and 1846 to 2877), the HCMV B gene code region sequence and its glycoprotein 52 kd antigenic domain sequence were amplified from the recombinant plasmid pBH1 DNA containing the HCMV B gene.
(20) The PCR amplified a 375-bp DNA fragment which was cloned and sequenced; the deduced amino acid sequence had significant identity with known TS sequences, including strict conservation of all phylogenetically invariant TS amino acid residues.
Booster
Definition:
Example Sentences:
(1) After 11 months, all vaccinees received a 20 micrograms booster of the recombinant vaccine.
(2) The serum-antibody titres after the primary and secondary injections or after a booster dose given before 12 months after the primary injection did not remain above the protective level in most of the sheep injected for longer than about 5 months.
(3) Twelve non-atopic and 27 atopic preschool children were studied to determine the effect of pertussis booster vaccination on cutaneous histamine sensitivity and IgE antibody response to the naturally-occurring ragweed aeroallergen.
(4) The four non responders received a supplementary vaccination a month later, beside the booster dose given one year later (T12).
(5) A booster vaccination at 56 wk induced a significant serologic response within 1 wk, suggesting an anamnestic response but titers began to decline within 8 wk in most foxes.
(6) The protective immunity elicited by TR-5 lasted longer and the booster effect was more prominent compared to the split vaccine.
(7) Of the 56 non-responders, 48 received a 40 micrograms booster dose of vaccine 6 weeks after completion of the initial course and a further eight seroconverted.
(8) Age, tumor stage, and the size of the booster field were found to be factors which influenced the survival rate with a fair statistical significance.
(9) 2nd and 3rd polio booster figures were 66.0 and 57.8% for 1982 and 76.5 and 74.8% for 1983.
(10) Four persons without anti-HBs after the basic vaccination received in turn two booster doses: at the 3rd and 46th month.
(11) Specific antibodies were further demonstrated by Western blot 4 days after the first booster immunization at 3 weeks.
(12) The booster radiation dose (1000 rad) given to the liver seems to be inadequate in preventing metastases there, as all the deaths were due to liver metastases.
(13) The choice of the carrier seemed to play an important role for both the level and maintenance of the secondary IgG response, attained as a consequence of a booster immunization with TT-alum.
(14) Acetaminophen did not result in significant reductions in reaction rates after the booster at 18 months.
(15) But the spacecraft's rocket boosters failed to ignite after it had been launched into a parking orbit around the Earth in November.
(16) We found a theophylline induced decrease of PGE2 production of M phi in normal but an increase in immunized animals which was less pronounced if given concomitantly with a booster injection.
(17) Boutik Services (+33 6 0958 0988) in 1850 has cots, booster seats, changing tables, buggies and child skis for hire.
(18) Antirabies gammaglobulin induced some inhibitory effect, but 2-3 booster injections of the tissue culture rabies vaccine completely compensated this effect.
(19) A polyvalent antiserum capable of neutralizing 82 isolates of feline calicivirus made from cats in various parts of North America was produced by the sequential inoculation of SPF cats at three-week intervals with feline calicivirus strains F-9, 68-2024 and FS, followed by a final booster inoculation two weeks after the third inoculation with all three strains combined.
(20) These findings support current recommendations for measles booster revaccination of school-age children and adolescents.