(n.) The column of bones in the back which sustains and gives firmness to the frame; the spine; the vertebral or spinal column.
(n.) Anything like , or serving the purpose of, a backbone.
(n.) Firmness; moral principle; steadfastness.
Example Sentences:
(1) A method for the introduction of side chains containing isonitrile (isocyanide, functional group) on the backbone of polysaccharides and other hydroxylic polymers was developed.
(2) The chromophore of octopus rhodopsin is 11-cis retinal, linked via a protonated Schiff base to the protein backbone.
(3) An unprincipled coward with the backbone of an amoeba."
(4) The Pr(III)-induced shifts for several resolved nonexchangeable backbone proton resonances were compared with calculated shifts using the known x-ray structure.
(5) Here we present images of polydeoxyadenylate molecules aligned in parallel, with their bases lying flat on a surface of highly oriented pyrolytic graphite and with their charged phosphodiester backbones protruding upwards.
(6) These data suggest that the somnogenic actions of these lipid A analogs depend on the acylation or phosphorylation pattern and backbone structures of the molecules.
(7) The resulting family of structures has a mean backbone rmsd of 0.63 A (N, C alpha, C', O atoms), excluding the segments containing residues 45-59 and 84-88.
(8) wt polypeptide backbone, modified by an endoglycosidase F-sensitive carbohydrate moiety.
(9) The backbone dynamics of Ca(2+)-saturated recombinant Drosophila calmodulin has been studied by 15N longitudinal and transverse relaxation experiments, combined with 15N(1H) NOE measurements.
(10) A central eight-stranded beta-pleated sheet is the main feature of the polypeptide backbone folding in dihydrofolate reductase.
(11) To investigate the topochemical preference of backbone and side chains, unusual amino acids, including beta-methylphenylalanine7 or 11, beta-methyltryptophan8, as well as backbone modifications such as retro-inverso structures have been incorporated.
(12) The angle obtained for the C alpha-D resonance was consistent with a single-stranded beta 6.3-helical model for the backbone but not with double-helical models.
(13) In the holopeptide corticotropin, the side chain-side chain effects, as reflected by the titration curves obtained from variations in the aromatic region, support the idea of an helical organization of part of the backbone even in aqueous solution.
(14) The local secondary structure was calculated from sequential and medium-range backbone NOEs with the double-iterated Kalman filter method [Altman, R. B., & Jardetzky, O.
(15) Although the (n-h) plots predict the stereochemical possibility of both right-handed and left-handed helices, nucleic acids apparently prefer right-handed conformation because of the energetics associated with the sugar-phosphate backbone and the base.
(16) And 96% of our grants go to African organisations, universities, scientists and small businesses to achieve a single goal: reduce hunger and poverty on our continent by unleashing the potential of the millions of small, family farmers who are the backbone of African agriculture and African economies.
(17) In addition the bare central backbone showed transverse striations.
(18) Misfolded models were constructed by introducing incorrect side chains onto polypeptide backbones: side chains of the alpha-helical hemerythrin were modeled on the beta-sheeted backbone of immunoglobulin VL domain, whereas those of the VL domain were similarly modeled on the hemerythrin backbone.
(19) Complete assignments were obtained for the backbone 1H, 15N and 13C resonances, using three-dimensional heteronuclear 1H NOE 1H-15N multiple-quantum coherence spectroscopy (3D-NOESY-HMQC) and three-dimensional heteronuclear total correlation 1H-15N multiple-quantum coherence spectroscopy (3D-TOCSY-HMQC) experiments on 15N-enriched HPr and an additional three-dimensional triple-resonance 1HN-15N-13C alpha correlation spectroscopy (HNCA) experiment on 13C, 15N-enriched HPr.
(20) Teh presence of the polyglycerol phosphate backbone and fatty acid was required for maximum immunosuppression of the primary immunoglobulin M response to sheep cells.
Support
Definition:
(v. t.) To bear by being under; to keep from falling; to uphold; to sustain, in a literal or physical sense; to prop up; to bear the weight of; as, a pillar supports a structure; an abutment supports an arch; the trunk of a tree supports the branches.
(v. t.) To endure without being overcome, exhausted, or changed in character; to sustain; as, to support pain, distress, or misfortunes.
(v. t.) To keep from failing or sinking; to solace under affictive circumstances; to assist; to encourage; to defend; as, to support the courage or spirits.
(v. t.) To assume and carry successfully, as the part of an actor; to represent or act; to sustain; as, to support the character of King Lear.
(v. t.) To furnish with the means of sustenance or livelihood; to maintain; to provide for; as, to support a family; to support the ministers of the gospel.
(v. t.) To carry on; to enable to continue; to maintain; as, to support a war or a contest; to support an argument or a debate.
(v. t.) To verify; to make good; to substantiate; to establish; to sustain; as, the testimony is not sufficient to support the charges; the evidence will not support the statements or allegations.
(v. t.) To vindicate; to maintain; to defend successfully; as, to be able to support one's own cause.
(v. t.) To uphold by aid or countenance; to aid; to help; to back up; as, to support a friend or a party; to support the present administration.
(v. t.) A attend as an honorary assistant; as, a chairman supported by a vice chairman; O'Connell left the prison, supported by his two sons.
(n.) The act, state, or operation of supporting, upholding, or sustaining.
(n.) That which upholds, sustains, or keeps from falling, as a prop, a pillar, or a foundation of any kind.
(n.) That which maintains or preserves from being overcome, falling, yielding, sinking, giving way, or the like; subsistence; maintenance; assistance; reenforcement; as, he gave his family a good support, the support of national credit; the assaulting column had the support of a battery.
Example Sentences:
(1) This excellent prognosis supports a regimen of conservative therapy for these patients.
(2) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
(3) Pathological and immunocytochemical data supported the diagnosis of medullary thyroid carcinoma.
(4) Technical factors that account for increased difficulty in these patients include: problems with guide catheter impaction and ostial trauma; inability to inflate the balloon with adequate guide catheter support; and need for increased intracoronary manipulation.
(5) Cantact placing reaction times were measured in cats which were either restrained in a hammock or supported in a conventional way.
(6) In a debate in the House of Commons, I will ask Britain, the US and other allies to convert generalised offers of help into more practical support with greater air cover, military surveillance and helicopter back-up, to hunt down the terrorists who abducted the girls.
(7) Models able to describe the events of cellular growth and division and the dynamics of cell populations are useful for the understanding of functional control mechanisms and for the theoretical support for automated analysis of flow cytometric data and of cell volume distributions.
(8) The presence of O-glycosidic linkages between carbohydrate and protein in the DF3 antigenic site was further supported by the presence of NaBH4-sensitive sites.
(9) Theresa May signals support for UK-EU membership deal Read more Faull’s fix, largely accepted by Britain, also ties the hands of national governments.
(10) Consensual but rationally weak criteria devised to extract inferences of causality from such results confirm the generic inadequacy of epidemiology in this area, and are unable to provide definitive scientific support to the perceived mandate for public health action.
(11) The program met with continued support and enthusiasm from nurse administrators, nursing unit managers, clinical educators, ward staff and course participants.
(12) Male sex, age under 19 or over 45, few social supports, and a history of previous suicide attempts are all factors associated with increased suicide rates.
(13) It also provides mechanical support for the collateral ligaments during valgus or varus stress of the knee.
(14) The data support the conclusion that accumulation of lipid II is responsible in some way for the hypersensitivity of delta rfbA mutants to SDS.
(15) The International Monetary Fund, which has long urged Nigeria to remove the subsidy, supports the move.
(16) He voiced support for refugees, trade unions, council housing, peace, international law and human rights.
(17) Training in social skills specific to fostering intimacy is suggested as a therapeutic step, and modifications to the social support measure for future use discussed.
(18) We want to be sure that the country that’s providing all the infrastructure and support to the business is the one that reaps the reward by being able to collect the tax,” he said.
(19) Evidence is presented in support of the hypothesis that fresh bat guano serves as a means of pathogenic fungi dissemination in caves.
(20) This postulate is supported by a limited study of the serovars present among the isolates.