(1) The value of K (4000 M-1) is similar for anti-BADE and 3-MCDE, although the latter is not intercalated in the classical sense since the short axis of the molecule is tilted closer to the axis of the DNA double helix.
(2) More than half a century after the US military draft put Elvis Presley's career on hold, his modern-day South Korean counterpart bade farewell to tearful fans this week as he prepared for two years' national service.
(3) However, the Portuguese said expectations had not been met as he bade his farewells.
(4) Significant differences were found between benzo[a]pyrene-diol-epoxide (BPDE)-DNA adducts, which align 5' in the minor groove, and benz[a]anthracene-diol-epoxide (BADE)-DNA and dibenz[a,c]anthracene-diol-epoxide-DNA adducts, which align 3' within the minor groove.
(5) Last month, Lily Allen bade goodbye to the internet.
(6) Doctor Who was the second most popular show, attracting an average of 8.3 million viewers, and achieved the biggest peak audience of the day, as 10.2 million bade farewell to Matt Smith and saw Capaldi's regeneration as the 12th Time Lord.
(7) I bade farewell to my old friend and my new friend and left the site around 12.30.
(8) And what kind of world greeted them when they bade farewell to the old year?
(9) There were also high-profile casualties from last year's MediaGuardian 100, including the Today presenter Evan Davis, X Factor judge Cheryl Cole, and Jonathan Ross, who bade farewell to the BBC at the weekend after nine years presenting his BBC1 chatshow and 11 years hosting the Saturday morning show on Radio 2.
(10) Chrysene-diol-epoxide-DNA adducts were found to have only a weak preference for 5' alignment and therefore share topographical characteristics with both BPDE-DNA and BADE-DNA adducts.
(11) It has previously been shown that the transcription of Mu is asymmetric and takes place on the heavy DNA strand (Bade, 1972; Wijffelman et al., 1974).
(12) "We are now being forced into war,' said Stephen Bading, a civil servant.
(13) The kinetics of the enzymatic conjugation of glutathione (GSH) with the anti-diastereoisomers of trans-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene (BPDE), trans-3,4-dihydroxy-1,2-epoxy-1,2,3, 4-tetrahydrobenz[a]anthracene (BADE) and trans-1,2- dihydroxy-3,4-epoxy-1,2,3,4-tetrahydrochrysene (CDE) catalyzed by transferase 4-4 from rat liver have been compared.
(14) It was unlike her father-in-law George HW Bush, who only served one term; that departure was a lot more abrupt.” Last month Obama bade farewell to staff at her beloved White House vegetable garden.
(15) Monoclonal antibodies produced against BADE-DNA also bound to chrysene diolepoxide-DNA but not to BPDE-DNA or to two other PAH-DNA adducts.
(16) In the case of the less tumorigenic syn-BADE, both the non-covalent complexes and the covalent adducts are of the site I-type.
(17) Last week alone, the doomed universal credit project bade farewell to yet another IT manager .
(18) Defoe would enter on 85 minutes for what was his final Premier League appearance at White Hart Lane before he joins FC Toronto on 28 February and he bade an emotional farewell to the fans.
(19) Both tumorigens, anti-BADE and 3-MCDE, undergo a marked re-orientation from a non-covalent site I to a covalent site II conformation upon binding chemically with the DNA bases, although a small fraction of the covalent anti-BADE adducts remains quasi-intercalated; in contrast, the alkyl substituents in 3-MCDE not only prevent the formation of intercalative physical complexes, but also the formation of site I covalent adducts.
(20) Monoclonal antibodies were produced against two different PAH-DNA adducts, benzo[a]pyrene diolepoxide-DNA (BPDE-DNA) and benz[a]anthracene diolepoxide-DNA (BADE-DNA).
Base
Definition:
(a.) Of little, or less than the usual, height; of low growth; as, base shrubs.
(a.) Low in place or position.
(a.) Of humble birth; or low degree; lowly; mean.
(a.) Illegitimate by birth; bastard.
(a.) Of little comparative value, as metal inferior to gold and silver, the precious metals.
(a.) Alloyed with inferior metal; debased; as, base coin; base bullion.
(a.) Morally low. Hence: Low-minded; unworthy; without dignity of sentiment; ignoble; mean; illiberal; menial; as, a base fellow; base motives; base occupations.
(a.) Not classical or correct.
(a.) Deep or grave in sound; as, the base tone of a violin.
(a.) Not held by honorable service; as, a base estate, one held by services not honorable; held by villenage. Such a tenure is called base, or low, and the tenant, a base tenant.
(n.) The bottom of anything, considered as its support, or that on which something rests for support; the foundation; as, the base of a statue.
(n.) Fig.: The fundamental or essential part of a thing; the essential principle; a groundwork.
(n.) The lower part of a wall, pier, or column, when treated as a separate feature, usually in projection, or especially ornamented.
(n.) The lower part of a complete architectural design, as of a monument; also, the lower part of any elaborate piece of furniture or decoration.
(n.) That extremity of a leaf, fruit, etc., at which it is attached to its support.
(n.) The positive, or non-acid component of a salt; a substance which, combined with an acid, neutralizes the latter and forms a salt; -- applied also to the hydroxides of the positive elements or radicals, and to certain organic bodies resembling them in their property of forming salts with acids.
(n.) The chief ingredient in a compound.
(n.) A substance used as a mordant.
(n.) The exterior side of the polygon, or that imaginary line which connects the salient angles of two adjacent bastions.
(n.) The line or surface constituting that part of a figure on which it is supposed to stand.
(n.) The number from which a mathematical table is constructed; as, the base of a system of logarithms.
(n.) A low, or deep, sound. (Mus.) (a) The lowest part; the deepest male voice. (b) One who sings, or the instrument which plays, base.
(n.) A place or tract of country, protected by fortifications, or by natural advantages, from which the operations of an army proceed, forward movements are made, supplies are furnished, etc.
(n.) The smallest kind of cannon.
(n.) That part of an organ by which it is attached to another more central organ.
(n.) The basal plane of a crystal.
(n.) The ground mass of a rock, especially if not distinctly crystalline.
(n.) The lower part of the field. See Escutcheon.
(n.) The housing of a horse.
(n.) A kind of skirt ( often of velvet or brocade, but sometimes of mailed armor) which hung from the middle to about the knees, or lower.
(n.) The lower part of a robe or petticoat.
(n.) An apron.
(n.) The point or line from which a start is made; a starting place or a goal in various games.
(n.) A line in a survey which, being accurately determined in length and position, serves as the origin from which to compute the distances and positions of any points or objects connected with it by a system of triangles.
(n.) A rustic play; -- called also prisoner's base, prison base, or bars.
(n.) Any one of the four bounds which mark the circuit of the infield.
(n.) To put on a base or basis; to lay the foundation of; to found, as an argument or conclusion; -- used with on or upon.
(a.) To abase; to let, or cast, down; to lower.
(a.) To reduce the value of; to debase.
Example Sentences:
(1) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
(2) However, CT will be insensitive in the detection of the more cephalic proximal lesions, especially those in the brain stem, basal cisterns, and skull base.
(3) Recently, the validity of the American Thoracic Society (ATS) standards for selection of spirometric test results has been questioned based on the finding of inverse dependence of FEV1 on effort.
(4) The omission of Crossrail 2 from the Conservative manifesto , in which other infrastructure projects were listed, was the clearest sign yet that there is little appetite in a Theresa May government for another London-based scheme.
(5) Squadron Leader Kevin Harris, commander of the Merlins at Camp Bastion, the main British base in Helmand, praised the crews, adding: "The Merlins will undergo an extensive programme of maintenance and cleaning before being packed up, ensuring they return to the UK in good order."
(6) The analysis is based on the personal experience of the authors with 117 cases and the review of 223 cases published in the literature.
(7) In the fall of 1975, 1,915 children in grades K through eight began a school-based program of supervised weekly rinsing with 0.2 percent aqueous solution of sodium fluoride in an unfluoridated community in the Finger Lakes area of upstate New York.
(8) Basing the prediction of student performance in medical school on intellective-cognitive abilities alone has proved to be more pertinent to academic achievement than to clinical practice.
(9) Induction of labor, based upon only (1) a finding of meconium in the amniocentesis group or (2) a positive test in the OCT group, was nearly three times more frequent in the amniocentesis group.
(10) Therefore, we have developed a powerful new microcomputer-based system which permits detailed investigations and evaluation of 3-D and 4-D (dynamic 3-D) biomedical images.
(11) The distance between the end of fic and the start of pabA was 31 base pairs.
(12) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(13) The method is based on two-dimensional scanning photon absorptiometry on the distal part of the forearm.
(14) At the fepB operator, a 31 base-pair Fur-protected region was identified, corresponding to positions -19 to +12 with respect to the transcriptional start site.
(15) Facebook Twitter Pinterest With a plot based around fake (or real?)
(16) Based on our results, we propose the following hypotheses for the neurochemical mechanisms of motion sickness: (1) the histaminergic neuron system is involved in the signs and symptoms of motion sickness, including vomiting; (2) the acetylcholinergic neuron system is involved in the processes of habituation to motion sickness, including neural store mechanisms; and (3) the catecholaminergic neuron system in the brain stem is not related to the development of motion sickness.
(17) Based on these results, we concluded that the inhibition of putrefactive anaerobe 3679 by sorbate resulted from a stringent-type regulatory response induced by the protonophoric activity of sorbic acid.
(18) Thus, mechanical restitution of the ventricle is a dynamic process that can be assessed using an elastance-based approach in the in situ heart.
(19) Mapping of the cross-link position between U2 and U6 RNAs is consistent with base-pairing between the 5' domain of U2 and the 3' end of U6 RNA.
(20) Descriptive features of the syndrome in children, adults and adolescents are given based on the respective work of Pine, Masterson and Kernberg.