(n.) A carpentry obstruction, stockade, or other obstacle made in a passage in order to stop an enemy.
(n.) A fortress or fortified town, on the frontier of a country, commanding an avenue of approach.
(n.) A fence or railing to mark the limits of a place, or to keep back a crowd.
(n.) An any obstruction; anything which hinders approach or attack.
(n.) Any limit or boundary; a line of separation.
Example Sentences:
(1) Here we have asked whether protection from blood-borne antigens afforded by the blood-brain barrier is related to the lack of MHC expression.
(2) We conclude that chloramphenicol resistance encoded by Tn1696 is due to a permeability barrier and hypothesize that the gene from P. aeruginosa may share a common ancestral origin with these genes from other gram-negative organisms.
(3) The findings clearly reveal that only the Sertoli-Sertoli junctional site forms a restrictive barrier.
(4) This suggests that a physiological mechanism exists which can increase the barrier pressure to gastrooesophageal reflux during periods of active secretion of the stomach, as occurs in digestion.
(5) Comparison of the 50% binding concentrations of the compounds for the various PBPs of the five strains with their antibacterial activity indicates that the different antibiotics are excluded to a greater or lesser degree by the outer membrane permeability barrier and that the exclusion is most pronounced in P. aeruginosa.
(6) Preservation of dopaminergic and H1 neurotransmission, probably within the blood barrier, is needed to allow the neuroendocrine transduction of cholinergic inputs, whereas the role of 5-HT neurotransmission remains uncertain.
(7) Their levels in urine are a useful indicator of the integrity of membrane barriers of the kidney glomerular capillary wall.
(8) The IgG index (formula: see text) corrects for the influence of serum protein abnormalities as well as a bloodbrain barrier damage and is, therefore, a better measure for the presence of an IgG elevation in CSF due to IgG synthesis, when compared with other IgG quotients commonly used.
(9) In the far east is the arid, depressed country leading down Hell’s Canyon, which bottoms out at the Snake River, which the wolves crossed when they moved from Idaho, and which they now treat more as a crosswalk than a barrier.
(10) No signs of the blood-brain barrier disruption were observed.
(11) Although no anatomical 'barrier' has been described, it has been suggested that the gel mucus and epithelial phospholipids are constituents.
(12) Despite their wide dispersion, Vmax and the stereological determinations correlated strongly at 2 mo of age, confirming that Vmax is a robust indicator of the surface area of the air-blood barrier.
(13) Developmental changes are delineated, with particular reference to recent work on the ovine blood-brain barrier.
(14) Features of barrier island physiography and ecology were studied relative to selective bait deployment and site biosecurity.
(15) This study sought to determine if and why barriers to the over-the-counter purchase of syringes in the St. Louis metropolitan area might exist, given that no ordinance prohibits such a sale there.
(16) It is suggested that the intercalated disc functioned as a barrier to the freezing process.
(17) To explain some of these results a theoretical model is presented to demonstrate that while short circuiting can block the passive ionic movement, it will cause an increase in the energy consumption of the system and introduce certain important changes in the ionic barriers and e.m.fs.
(18) Our results show that paramagnetic enhancement with T1-weighted imaging adds specificity and enables rapid assessment of abnormalities of the blood-brain barrier.
(19) A functional impairment of the amino acid transport systems at the level of the blood-brain barrier seems to play a crucial role in causing deleterious modifications of the synaptic neurotransmission in the central nervous system.
(20) There was a significant correlation between the lesion index and the PD reduction, although the integrity of the resting gastric mucosal barrier remained unaltered.
Gate
Definition:
(n.) A large door or passageway in the wall of a city, of an inclosed field or place, or of a grand edifice, etc.; also, the movable structure of timber, metal, etc., by which the passage can be closed.
(n.) An opening for passage in any inclosing wall, fence, or barrier; or the suspended framework which closes or opens a passage. Also, figuratively, a means or way of entrance or of exit.
(n.) A door, valve, or other device, for stopping the passage of water through a dam, lock, pipe, etc.
(n.) The places which command the entrances or access; hence, place of vantage; power; might.
(n.) In a lock tumbler, the opening for the stump of the bolt to pass through or into.
(n.) The channel or opening through which metal is poured into the mold; the ingate.
(n.) The waste piece of metal cast in the opening; a sprue or sullage piece.
(v. t.) To supply with a gate.
(v. t.) To punish by requiring to be within the gates at an earlier hour than usual.
(n.) A way; a path; a road; a street (as in Highgate).
(n.) Manner; gait.
Example Sentences:
(1) Modulation of the voltage-gated K+ conductance in T-lymphocytes by substance P was examined.
(2) She said that even as she approached the gates, she was debating with the boy’s father whether to let the first-grader enter.
(3) The Brandenburg Gate was lit up in the colours of the German flag.
(4) The committee is chaired by John Thompson, the board's lead independent director, and includes Microsoft founder and chairman, Bill Gates, as well as other board members Chuck Noski and Steve Luczo.
(5) Right ventricular volumes were determined in 12 patients with different levels of right and left ventricular function by magnetic resonance imaging (MRI) using an ECG gated multisection technique in planes perpendicular to the diastolic position of the interventricular septum.
(6) Britain has been the Gates foundation’s second largest recipient, receiving 25 grants worth $156m since 2003.
(7) A method using selective saturation pulses and gated spin-echo MRI automatically corrects for this motion and thus eliminates misregistration artifact from regional function analysis.
(8) Gated blood pool images were stored in modified left anterior oblique views by the multiple gated method (28 frames per beat) after the in vivo labeling of erythrocytes using 25 mCi 99m-Tc.
(9) Four days after a 5 minute bilateral carotid artery occlusion, receptor autoradiography was performed to measure the binding of [35S]t-butylbicyclophosphorothionate (TBPS) to the GABA-gated chloride channel.
(10) Similar responses were obtained with gated noise bursts and by pauses in a series of clicks.
(11) The estimated forward (k) and backward (1) rate constants are: 2.45 x I05 M-1 s- and 0.23 x 103 s-1, respectively, for k and I for the case when the drug is trapped by both activation and inactivation gates, and 3.58 x 105 M-l s-l and 4.15 x 10-3 S-l for the case when the drug is not trapped.
(12) p-NCS-TBOB should prove useful in electrophysiological and biochemical studies examining the properties of GABA-gated Cl- channels.
(13) The involvement of the endothelium and the role of change in membrane potential are evaluated and lead to the conclusion that pressure and flow effects do not depend exclusively on the release of endothelial factors nor the activation of voltage-gated Ca2+ channels.
(14) Norwich Ownership Delia Smith and her husband Michael Wynn Jones own 53.1% of the club’s shares; deputy chairman Michael Foulger owns approximately 16% Gate receipts £12m Broadcasting and media £70m Catering £4m Commercial & other income £12m Net debt Not stated; £2.7m bank overdraft, no directors’ loans.
(15) This conductance is activated when the cis side is made positive, with an apparent gating charge of 3.
(16) In addition to improved image quality, the characteristics of 99mTc sestamibi allow gated planar or SPECT perfusion images to be obtained.
(17) Perijunctional Na+ channels had the same voltage dependence, gating kinetics and sensitivity to tetrodotoxin as extrajunctional Na+ channels, suggesting that these cells express a single type of Na+ channel.
(18) Charge conservation analysis explicitly includes the gating charge when applied in the laboratory frame.
(19) We found the incorporated channels to be insensitive to calcium and octanol, and in most cases to pH in the range of 5-7, suggesting that either these agents do not interact directly with the junctional channels or that the corresponding gating regions are inactivated during the isolation and reconstitution procedures.
(20) "You could be in an open-world single-player environment where you can go up to a gate and when you enter that base, you're walking into a multiplayer map.