(a.) Of little, or less than the usual, height; of low growth; as, base shrubs.
(a.) Low in place or position.
(a.) Of humble birth; or low degree; lowly; mean.
(a.) Illegitimate by birth; bastard.
(a.) Of little comparative value, as metal inferior to gold and silver, the precious metals.
(a.) Alloyed with inferior metal; debased; as, base coin; base bullion.
(a.) Morally low. Hence: Low-minded; unworthy; without dignity of sentiment; ignoble; mean; illiberal; menial; as, a base fellow; base motives; base occupations.
(a.) Not classical or correct.
(a.) Deep or grave in sound; as, the base tone of a violin.
(a.) Not held by honorable service; as, a base estate, one held by services not honorable; held by villenage. Such a tenure is called base, or low, and the tenant, a base tenant.
(n.) The bottom of anything, considered as its support, or that on which something rests for support; the foundation; as, the base of a statue.
(n.) Fig.: The fundamental or essential part of a thing; the essential principle; a groundwork.
(n.) The lower part of a wall, pier, or column, when treated as a separate feature, usually in projection, or especially ornamented.
(n.) The lower part of a complete architectural design, as of a monument; also, the lower part of any elaborate piece of furniture or decoration.
(n.) That extremity of a leaf, fruit, etc., at which it is attached to its support.
(n.) The positive, or non-acid component of a salt; a substance which, combined with an acid, neutralizes the latter and forms a salt; -- applied also to the hydroxides of the positive elements or radicals, and to certain organic bodies resembling them in their property of forming salts with acids.
(n.) The chief ingredient in a compound.
(n.) A substance used as a mordant.
(n.) The exterior side of the polygon, or that imaginary line which connects the salient angles of two adjacent bastions.
(n.) The line or surface constituting that part of a figure on which it is supposed to stand.
(n.) The number from which a mathematical table is constructed; as, the base of a system of logarithms.
(n.) A low, or deep, sound. (Mus.) (a) The lowest part; the deepest male voice. (b) One who sings, or the instrument which plays, base.
(n.) A place or tract of country, protected by fortifications, or by natural advantages, from which the operations of an army proceed, forward movements are made, supplies are furnished, etc.
(n.) The smallest kind of cannon.
(n.) That part of an organ by which it is attached to another more central organ.
(n.) The basal plane of a crystal.
(n.) The ground mass of a rock, especially if not distinctly crystalline.
(n.) The lower part of the field. See Escutcheon.
(n.) The housing of a horse.
(n.) A kind of skirt ( often of velvet or brocade, but sometimes of mailed armor) which hung from the middle to about the knees, or lower.
(n.) The lower part of a robe or petticoat.
(n.) An apron.
(n.) The point or line from which a start is made; a starting place or a goal in various games.
(n.) A line in a survey which, being accurately determined in length and position, serves as the origin from which to compute the distances and positions of any points or objects connected with it by a system of triangles.
(n.) A rustic play; -- called also prisoner's base, prison base, or bars.
(n.) Any one of the four bounds which mark the circuit of the infield.
(n.) To put on a base or basis; to lay the foundation of; to found, as an argument or conclusion; -- used with on or upon.
(a.) To abase; to let, or cast, down; to lower.
(a.) To reduce the value of; to debase.
Example Sentences:
(1) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
(2) However, CT will be insensitive in the detection of the more cephalic proximal lesions, especially those in the brain stem, basal cisterns, and skull base.
(3) Recently, the validity of the American Thoracic Society (ATS) standards for selection of spirometric test results has been questioned based on the finding of inverse dependence of FEV1 on effort.
(4) The omission of Crossrail 2 from the Conservative manifesto , in which other infrastructure projects were listed, was the clearest sign yet that there is little appetite in a Theresa May government for another London-based scheme.
(5) Squadron Leader Kevin Harris, commander of the Merlins at Camp Bastion, the main British base in Helmand, praised the crews, adding: "The Merlins will undergo an extensive programme of maintenance and cleaning before being packed up, ensuring they return to the UK in good order."
(6) The analysis is based on the personal experience of the authors with 117 cases and the review of 223 cases published in the literature.
(7) In the fall of 1975, 1,915 children in grades K through eight began a school-based program of supervised weekly rinsing with 0.2 percent aqueous solution of sodium fluoride in an unfluoridated community in the Finger Lakes area of upstate New York.
(8) Basing the prediction of student performance in medical school on intellective-cognitive abilities alone has proved to be more pertinent to academic achievement than to clinical practice.
(9) Induction of labor, based upon only (1) a finding of meconium in the amniocentesis group or (2) a positive test in the OCT group, was nearly three times more frequent in the amniocentesis group.
(10) Therefore, we have developed a powerful new microcomputer-based system which permits detailed investigations and evaluation of 3-D and 4-D (dynamic 3-D) biomedical images.
(11) The distance between the end of fic and the start of pabA was 31 base pairs.
(12) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(13) The method is based on two-dimensional scanning photon absorptiometry on the distal part of the forearm.
(14) At the fepB operator, a 31 base-pair Fur-protected region was identified, corresponding to positions -19 to +12 with respect to the transcriptional start site.
(15) Facebook Twitter Pinterest With a plot based around fake (or real?)
(16) Based on our results, we propose the following hypotheses for the neurochemical mechanisms of motion sickness: (1) the histaminergic neuron system is involved in the signs and symptoms of motion sickness, including vomiting; (2) the acetylcholinergic neuron system is involved in the processes of habituation to motion sickness, including neural store mechanisms; and (3) the catecholaminergic neuron system in the brain stem is not related to the development of motion sickness.
(17) Based on these results, we concluded that the inhibition of putrefactive anaerobe 3679 by sorbate resulted from a stringent-type regulatory response induced by the protonophoric activity of sorbic acid.
(18) Thus, mechanical restitution of the ventricle is a dynamic process that can be assessed using an elastance-based approach in the in situ heart.
(19) Mapping of the cross-link position between U2 and U6 RNAs is consistent with base-pairing between the 5' domain of U2 and the 3' end of U6 RNA.
(20) Descriptive features of the syndrome in children, adults and adolescents are given based on the respective work of Pine, Masterson and Kernberg.
Guanidine
Definition:
(n.) A strongly alkaline base, CN3H5, formed by the oxidation of guanin, and also obtained combined with methyl in the decomposition of creatin. Boiled with dilute sulphuric acid, it yields urea and ammonia.
Example Sentences:
(1) In a previous report dealing with the guanidine hydrochloride protocol for the extraction of RNA from mouse peritoneal macrophages, we identified a major source of RNA-degrading activity and showed that its removal early in the extraction procedure resulted in a more dependable method for the recovery of high-quality RNA.
(2) Guanidine hydrochloride was as effective as the best organic solvent in increasing the solubility of deoxyhemoglobin S; urea was far less effective.
(3) Circular dichroism studies show that the conformation of each subunit is unusually resistant to change in 6 M guanidine HC1 at 25 degrees C. This suggests that exposure of the epitope by dissociation requires minimal or no unfolding of subunits.
(4) It was found that alpha-1-AT easily forms polymers and higher aggregates when exposed to denaturing agents such as 8 M urea and 6 M guanidine.
(5) However, when periplasmic-side-out vesicles, prepared by cytochrome c affinity chromatography, were treated with the guanidinating reagent, three of the light-harvesting proteins (B850 alpha, B850 beta, and B870 beta) were not labeled.
(6) The data relative to the guanidine-induced unfolding show a sigmoidal increase of the distribution width, which is due to the transition of the protein structure from the native to the random-coiled state.
(7) Pretreatment of Con A-Sepharose 4B with urea or guanidine minimized this problem.
(8) The inactivation of equine liver alcohol dehydrogenase by guanidine hydrochloride and urea has been studied by monitoring the intrinsic tryptophan fluorescence and phosphorescence emission.
(9) The conformational stabilities of bovine lens gamma-crystallin fractions II, IIIA, IIIB, and IVA and those modified with glutathione were compared by studying the thermal and guanidine hydrochloride (Gdn-HCl) denaturation behavior.
(10) CD and viscosity measurements indicate that guanidine .
(11) The recombinant protein, His6-5.1-(NANP)19 with an apparent molecular size of 40 kDa could be highly purified by a combination of 4 steps: (1) release and solubilization of the recombinant fusion protein from E. coli in the presence of 6 M guanidine-HCl; (2) precipitation of over 60% of the bacterial proteins by the addition of ammonium sulphate to 50% saturation; (3) affinity chromatography on a Ni(2+)-chelate column in the presence of 6 M guanidine-HCl; (4) adsorption onto a cation exchange resin in the presence of 6 M urea, and elution with an increasing NaCl gradient.
(12) The most prominent band observed in the heart guanidine extract by electrophoresis had a molecular weight of 85,000 and minor components (Mr = 360,000 and 170,000) were also detected; approximately 20% of the proteoglycan associated [35S]sulfate was present in heparan sulfate chains.
(13) A third derivative with a free amino group at the amino terminus was prepared by guanidination of the 4 lysine residues with o-methylisourea.
(14) Impromidine (1) is a potent and selective histamine H2 receptor agonist and its structure comprises a strongly basic guanidine group containing two different imidazole-containing side chains.
(15) In the present study, the reversibility of the unfolding-refolding process induced by guanidine hydrochloride was investigated for the intact protein and the isolated domains.
(16) The insolubilized C3 was eluted with 5 M guanidine and, after extensive dialysis, was reduced with 0.2 M 2-mercaptoethanol and electrophoresed on SDS-polyacrylamide gels.
(17) Effects of the K+ channel blocking agent, glyburide, on the actions of two K+ channel openers, BRL 34915 (cromakalim) and P 1060 (Leo), a potent pinacidil derivative (N-(t-butyl)-N"-cyano-N'-3-pyridyl-guanidine), were ascertained.
(18) The Asn-108 codon was detected using a primer of 17 nucleotides with an adenosine at its 3' end, the Thr-108 codon with a 14-mer primer ending with a cytosine and the Ser-108 codon with a 16-mer containing guanidine at the critical 3' end.
(19) A two-stage reversible denaturation of the enzyme by guanidine HCl was observed with midpoints of 0.25 and 1.75 M, respectively.
(20) Protein unfolding was detected by ellipticity changes at 222 nm with increasing concentrations of guanidine hydrochloride (GdnHCl).