What's the difference between base and homology?

Base


Definition:

  • (a.) Of little, or less than the usual, height; of low growth; as, base shrubs.
  • (a.) Low in place or position.
  • (a.) Of humble birth; or low degree; lowly; mean.
  • (a.) Illegitimate by birth; bastard.
  • (a.) Of little comparative value, as metal inferior to gold and silver, the precious metals.
  • (a.) Alloyed with inferior metal; debased; as, base coin; base bullion.
  • (a.) Morally low. Hence: Low-minded; unworthy; without dignity of sentiment; ignoble; mean; illiberal; menial; as, a base fellow; base motives; base occupations.
  • (a.) Not classical or correct.
  • (a.) Deep or grave in sound; as, the base tone of a violin.
  • (a.) Not held by honorable service; as, a base estate, one held by services not honorable; held by villenage. Such a tenure is called base, or low, and the tenant, a base tenant.
  • (n.) The bottom of anything, considered as its support, or that on which something rests for support; the foundation; as, the base of a statue.
  • (n.) Fig.: The fundamental or essential part of a thing; the essential principle; a groundwork.
  • (n.) The lower part of a wall, pier, or column, when treated as a separate feature, usually in projection, or especially ornamented.
  • (n.) The lower part of a complete architectural design, as of a monument; also, the lower part of any elaborate piece of furniture or decoration.
  • (n.) That extremity of a leaf, fruit, etc., at which it is attached to its support.
  • (n.) The positive, or non-acid component of a salt; a substance which, combined with an acid, neutralizes the latter and forms a salt; -- applied also to the hydroxides of the positive elements or radicals, and to certain organic bodies resembling them in their property of forming salts with acids.
  • (n.) The chief ingredient in a compound.
  • (n.) A substance used as a mordant.
  • (n.) The exterior side of the polygon, or that imaginary line which connects the salient angles of two adjacent bastions.
  • (n.) The line or surface constituting that part of a figure on which it is supposed to stand.
  • (n.) The number from which a mathematical table is constructed; as, the base of a system of logarithms.
  • (n.) A low, or deep, sound. (Mus.) (a) The lowest part; the deepest male voice. (b) One who sings, or the instrument which plays, base.
  • (n.) A place or tract of country, protected by fortifications, or by natural advantages, from which the operations of an army proceed, forward movements are made, supplies are furnished, etc.
  • (n.) The smallest kind of cannon.
  • (n.) That part of an organ by which it is attached to another more central organ.
  • (n.) The basal plane of a crystal.
  • (n.) The ground mass of a rock, especially if not distinctly crystalline.
  • (n.) The lower part of the field. See Escutcheon.
  • (n.) The housing of a horse.
  • (n.) A kind of skirt ( often of velvet or brocade, but sometimes of mailed armor) which hung from the middle to about the knees, or lower.
  • (n.) The lower part of a robe or petticoat.
  • (n.) An apron.
  • (n.) The point or line from which a start is made; a starting place or a goal in various games.
  • (n.) A line in a survey which, being accurately determined in length and position, serves as the origin from which to compute the distances and positions of any points or objects connected with it by a system of triangles.
  • (n.) A rustic play; -- called also prisoner's base, prison base, or bars.
  • (n.) Any one of the four bounds which mark the circuit of the infield.
  • (n.) To put on a base or basis; to lay the foundation of; to found, as an argument or conclusion; -- used with on or upon.
  • (a.) To abase; to let, or cast, down; to lower.
  • (a.) To reduce the value of; to debase.

Example Sentences:

  • (1) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
  • (2) However, CT will be insensitive in the detection of the more cephalic proximal lesions, especially those in the brain stem, basal cisterns, and skull base.
  • (3) Recently, the validity of the American Thoracic Society (ATS) standards for selection of spirometric test results has been questioned based on the finding of inverse dependence of FEV1 on effort.
  • (4) The omission of Crossrail 2 from the Conservative manifesto , in which other infrastructure projects were listed, was the clearest sign yet that there is little appetite in a Theresa May government for another London-based scheme.
  • (5) Squadron Leader Kevin Harris, commander of the Merlins at Camp Bastion, the main British base in Helmand, praised the crews, adding: "The Merlins will undergo an extensive programme of maintenance and cleaning before being packed up, ensuring they return to the UK in good order."
  • (6) The analysis is based on the personal experience of the authors with 117 cases and the review of 223 cases published in the literature.
  • (7) In the fall of 1975, 1,915 children in grades K through eight began a school-based program of supervised weekly rinsing with 0.2 percent aqueous solution of sodium fluoride in an unfluoridated community in the Finger Lakes area of upstate New York.
  • (8) Basing the prediction of student performance in medical school on intellective-cognitive abilities alone has proved to be more pertinent to academic achievement than to clinical practice.
  • (9) Induction of labor, based upon only (1) a finding of meconium in the amniocentesis group or (2) a positive test in the OCT group, was nearly three times more frequent in the amniocentesis group.
  • (10) Therefore, we have developed a powerful new microcomputer-based system which permits detailed investigations and evaluation of 3-D and 4-D (dynamic 3-D) biomedical images.
  • (11) The distance between the end of fic and the start of pabA was 31 base pairs.
  • (12) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
  • (13) The method is based on two-dimensional scanning photon absorptiometry on the distal part of the forearm.
  • (14) At the fepB operator, a 31 base-pair Fur-protected region was identified, corresponding to positions -19 to +12 with respect to the transcriptional start site.
  • (15) Facebook Twitter Pinterest With a plot based around fake (or real?)
  • (16) Based on our results, we propose the following hypotheses for the neurochemical mechanisms of motion sickness: (1) the histaminergic neuron system is involved in the signs and symptoms of motion sickness, including vomiting; (2) the acetylcholinergic neuron system is involved in the processes of habituation to motion sickness, including neural store mechanisms; and (3) the catecholaminergic neuron system in the brain stem is not related to the development of motion sickness.
  • (17) Based on these results, we concluded that the inhibition of putrefactive anaerobe 3679 by sorbate resulted from a stringent-type regulatory response induced by the protonophoric activity of sorbic acid.
  • (18) Thus, mechanical restitution of the ventricle is a dynamic process that can be assessed using an elastance-based approach in the in situ heart.
  • (19) Mapping of the cross-link position between U2 and U6 RNAs is consistent with base-pairing between the 5' domain of U2 and the 3' end of U6 RNA.
  • (20) Descriptive features of the syndrome in children, adults and adolescents are given based on the respective work of Pine, Masterson and Kernberg.

Homology


Definition:

  • (n.) The quality of being homologous; correspondence; relation; as, the homologyof similar polygons.
  • (n.) Correspondence or relation in type of structure in contradistinction to similarity of function; as, the relation in structure between the leg and arm of a man; or that between the arm of a man, the fore leg of a horse, the wing of a bird, and the fin of a fish, all these organs being modifications of one type of structure.
  • (n.) The correspondence or resemblance of substances belonging to the same type or series; a similarity of composition varying by a small, regular difference, and usually attended by a regular variation in physical properties; as, there is an homology between methane, CH4, ethane, C2H6, propane, C3H8, etc., all members of the paraffin series. In an extended sense, the term is applied to the relation between chemical elements of the same group; as, chlorine, bromine, and iodine are said to be in homology with each other. Cf. Heterology.

Example Sentences:

  • (1) Trifluoroacetylated rabbit serum albumin was 5 times more reactive with these antibodies and thus more antigenic than the homologous acetylated moiety confirming the importance of the trifluoromethyl moiety as an epitope in the immunogen in vivo.
  • (2) The ORF2 showed homology with the Escherichia coli regulatory gene ompR, and ORF4 showed homology with E. coli and Rhizobium meliloti regulatory genes fnr and fixK, respectively.
  • (3) Nucleotide sequence analysis of cDNAs for asparagine synthetase (AS) of Pisum sativum has uncovered two distinct AS mRNAs (AS1 and AS2) encoding polypeptides that are highly homologous to the human AS enzyme.
  • (4) In four main regions the conservation varied from 83-91% while in the remaining regions the homology dropped to between 56-62%.
  • (5) It has 61% homology with tRNA(Leu)(anticodon m5CAA) and 63% homology with tRNA(Leu)(anticodon UAG), the two other known yeast tRNAs(Leu).
  • (6) The specified region of the inner E2 core domain was highly homologous to the region of the E2 subunit of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase.
  • (7) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
  • (8) This unusual insertion could affect the interaction of cat CD4 with class II molecules, or with FIV, a feline homolog of HIV.
  • (9) On the basis of primary sequence homology with other known Pseudomonas lipases, a number of putative active site residues located in conserved areas were found.
  • (10) Extensive sequence homologies and other genetic features are shared with the related oncogenic virus, human papillomavirus type 16, especially in the major reading frames.
  • (11) Since the plasmid-cured strains did not contain DNA sequences homologous to plasmid DNA, the gene for the free-inclusion protein must be encoded in the chromosome.
  • (12) Examination of the deduced amino acid sequence revealed an apparent homology to cAMP binding sites in several other proteins.
  • (13) Thus, introduction of arginine in position 5 with a hydrophobic amino acid in position 6 is compatible with high potency in several biological systems and results in compounds with lowered potency to release histamine compared to homologous peptides with tyrosine in position 5 and D-arginine in position 6.
  • (14) This receptor and a growing family of related cytokine receptors share homologous extracellular features, including a well-conserved WSXWS motif.
  • (15) Amino acid analysis indicated a significant number of serine amino acids: N-terminal sequence data demonstrated a high level of homology; and trypsin digestion followed by reversed-phase HPLC indicated the possibility of multiple phosphorylation sites.
  • (16) Homologous insemination in 52 couples during a period of one year yields a conception rate of 38.5%.
  • (17) The region is distinctive in that the sequence is absent from the homologous domain of the erythroid alpha chain and diverges from the normal internal repeat structure observed throughout other spectrins.
  • (18) Surrounding intact ipsilateral structures are more important for the recovery of some of the language functions, such as motor output and phonemic assembly, than homologous contralateral structures.
  • (19) The results show that in both viral DNAs cleavage occurs at the origin and at one additional site which shows striking sequence homology with the origin region.
  • (20) The most striking homology was to yeast SEC7 in the central domain of the gene (57% identical over 466 bp) and also the protein level (42% identical amino acids; 39% conserved amino acids).