What's the difference between base and polybasic?

Base


Definition:

  • (a.) Of little, or less than the usual, height; of low growth; as, base shrubs.
  • (a.) Low in place or position.
  • (a.) Of humble birth; or low degree; lowly; mean.
  • (a.) Illegitimate by birth; bastard.
  • (a.) Of little comparative value, as metal inferior to gold and silver, the precious metals.
  • (a.) Alloyed with inferior metal; debased; as, base coin; base bullion.
  • (a.) Morally low. Hence: Low-minded; unworthy; without dignity of sentiment; ignoble; mean; illiberal; menial; as, a base fellow; base motives; base occupations.
  • (a.) Not classical or correct.
  • (a.) Deep or grave in sound; as, the base tone of a violin.
  • (a.) Not held by honorable service; as, a base estate, one held by services not honorable; held by villenage. Such a tenure is called base, or low, and the tenant, a base tenant.
  • (n.) The bottom of anything, considered as its support, or that on which something rests for support; the foundation; as, the base of a statue.
  • (n.) Fig.: The fundamental or essential part of a thing; the essential principle; a groundwork.
  • (n.) The lower part of a wall, pier, or column, when treated as a separate feature, usually in projection, or especially ornamented.
  • (n.) The lower part of a complete architectural design, as of a monument; also, the lower part of any elaborate piece of furniture or decoration.
  • (n.) That extremity of a leaf, fruit, etc., at which it is attached to its support.
  • (n.) The positive, or non-acid component of a salt; a substance which, combined with an acid, neutralizes the latter and forms a salt; -- applied also to the hydroxides of the positive elements or radicals, and to certain organic bodies resembling them in their property of forming salts with acids.
  • (n.) The chief ingredient in a compound.
  • (n.) A substance used as a mordant.
  • (n.) The exterior side of the polygon, or that imaginary line which connects the salient angles of two adjacent bastions.
  • (n.) The line or surface constituting that part of a figure on which it is supposed to stand.
  • (n.) The number from which a mathematical table is constructed; as, the base of a system of logarithms.
  • (n.) A low, or deep, sound. (Mus.) (a) The lowest part; the deepest male voice. (b) One who sings, or the instrument which plays, base.
  • (n.) A place or tract of country, protected by fortifications, or by natural advantages, from which the operations of an army proceed, forward movements are made, supplies are furnished, etc.
  • (n.) The smallest kind of cannon.
  • (n.) That part of an organ by which it is attached to another more central organ.
  • (n.) The basal plane of a crystal.
  • (n.) The ground mass of a rock, especially if not distinctly crystalline.
  • (n.) The lower part of the field. See Escutcheon.
  • (n.) The housing of a horse.
  • (n.) A kind of skirt ( often of velvet or brocade, but sometimes of mailed armor) which hung from the middle to about the knees, or lower.
  • (n.) The lower part of a robe or petticoat.
  • (n.) An apron.
  • (n.) The point or line from which a start is made; a starting place or a goal in various games.
  • (n.) A line in a survey which, being accurately determined in length and position, serves as the origin from which to compute the distances and positions of any points or objects connected with it by a system of triangles.
  • (n.) A rustic play; -- called also prisoner's base, prison base, or bars.
  • (n.) Any one of the four bounds which mark the circuit of the infield.
  • (n.) To put on a base or basis; to lay the foundation of; to found, as an argument or conclusion; -- used with on or upon.
  • (a.) To abase; to let, or cast, down; to lower.
  • (a.) To reduce the value of; to debase.

Example Sentences:

  • (1) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
  • (2) However, CT will be insensitive in the detection of the more cephalic proximal lesions, especially those in the brain stem, basal cisterns, and skull base.
  • (3) Recently, the validity of the American Thoracic Society (ATS) standards for selection of spirometric test results has been questioned based on the finding of inverse dependence of FEV1 on effort.
  • (4) The omission of Crossrail 2 from the Conservative manifesto , in which other infrastructure projects were listed, was the clearest sign yet that there is little appetite in a Theresa May government for another London-based scheme.
  • (5) Squadron Leader Kevin Harris, commander of the Merlins at Camp Bastion, the main British base in Helmand, praised the crews, adding: "The Merlins will undergo an extensive programme of maintenance and cleaning before being packed up, ensuring they return to the UK in good order."
  • (6) The analysis is based on the personal experience of the authors with 117 cases and the review of 223 cases published in the literature.
  • (7) In the fall of 1975, 1,915 children in grades K through eight began a school-based program of supervised weekly rinsing with 0.2 percent aqueous solution of sodium fluoride in an unfluoridated community in the Finger Lakes area of upstate New York.
  • (8) Basing the prediction of student performance in medical school on intellective-cognitive abilities alone has proved to be more pertinent to academic achievement than to clinical practice.
  • (9) Induction of labor, based upon only (1) a finding of meconium in the amniocentesis group or (2) a positive test in the OCT group, was nearly three times more frequent in the amniocentesis group.
  • (10) Therefore, we have developed a powerful new microcomputer-based system which permits detailed investigations and evaluation of 3-D and 4-D (dynamic 3-D) biomedical images.
  • (11) The distance between the end of fic and the start of pabA was 31 base pairs.
  • (12) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
  • (13) The method is based on two-dimensional scanning photon absorptiometry on the distal part of the forearm.
  • (14) At the fepB operator, a 31 base-pair Fur-protected region was identified, corresponding to positions -19 to +12 with respect to the transcriptional start site.
  • (15) Facebook Twitter Pinterest With a plot based around fake (or real?)
  • (16) Based on our results, we propose the following hypotheses for the neurochemical mechanisms of motion sickness: (1) the histaminergic neuron system is involved in the signs and symptoms of motion sickness, including vomiting; (2) the acetylcholinergic neuron system is involved in the processes of habituation to motion sickness, including neural store mechanisms; and (3) the catecholaminergic neuron system in the brain stem is not related to the development of motion sickness.
  • (17) Based on these results, we concluded that the inhibition of putrefactive anaerobe 3679 by sorbate resulted from a stringent-type regulatory response induced by the protonophoric activity of sorbic acid.
  • (18) Thus, mechanical restitution of the ventricle is a dynamic process that can be assessed using an elastance-based approach in the in situ heart.
  • (19) Mapping of the cross-link position between U2 and U6 RNAs is consistent with base-pairing between the 5' domain of U2 and the 3' end of U6 RNA.
  • (20) Descriptive features of the syndrome in children, adults and adolescents are given based on the respective work of Pine, Masterson and Kernberg.

Polybasic


Definition:

  • (a.) Capable of neutralizing, or of combining with, several molecules of a monacid base; having several hydrogen atoms capable of being replaced by basic radicals; -- said of certain acids; as, sulphuric acid is polybasic.

Example Sentences:

  • (1) The polypeptide does not, however, have a deswelling effect on the tissue; the ultimate reduction in swelling is influenced by the absolute amount of polybase which enters the tissue during the swelling process.
  • (2) Only casein kinase-2 and a spleen tyrosine protein kinase (TPK-III) proved effective, their phosphorylation efficiency being dramatically enhanced by histones and other polybasic peptides while being depressed by 50 microM Ca2+.
  • (3) Within the hypervariable domain of p21K-ras(B), which is not palmitoylated, we have identified a novel plasma membrane targeting signal consisting of a polybasic domain that also acts in combination with the CAAX motif.
  • (4) The polybasic acids trypan blue and its analogue trypan red, bromphenol blue and its analogue bromthymol blue at concentrations of 0.22 mM and ethylenediaminetetra-acetic acid (EDTA) at a concentration of 1 mM are strong inhibitors of the enzyme.3.
  • (5) Mutational analysis of p21ras has shown that plasma membrane targeting requires the combination of a CAAX motif with a polybasic domain of six lysine residues or a nearby palmitoylation site.
  • (6) A method for the isolation of vacuoles based on polybase induced lysis of protoplasts of the cell wall deficient Neurospora crassa slime variant is described.
  • (7) Plasma membrane targeting of p21K-ras(B) requires a CAAX motif and a polybasic domain.
  • (8) The swelling kinetics of polybasic gels consisting of copolymers of methyl methacrylate and dimethylaminoethyl methacrylate are studied in solutions at various acidic pH values, with monoacidic derivatives of acetic acid added as buffers.
  • (9) Polybasic acids affording insoluble salts were evaluated for their ability to form drug:acid:metal complexes with the polyvalent metal ions, Zn++, Al+++, Mg++ and Ca++.
  • (10) Modification of BHV tissue was obtained by covalently binding protamine sulfate, a polybasic peptide, via glutaraldehyde.
  • (11) Potassium chloride in high concentrations and calcium chloride in low concentrations inhibited polybase induced lysis of spheroplasts by preventing or even reversing the polybase adsorption.
  • (12) Profilin with one covalently attached actin CNBr peptide was purified by gel filtration followed by gel electrophoresis and electroblotting on polybase-coated glass-fiber membranes.
  • (13) Modification of BHV tissue was obtained by covalently binding protamine sulfate, a polybasic peptide, via formaldehyde and subsequent glutaraldehyde tissue crosslinking.
  • (14) With labeled proteins used as models, it is found that the transport proceeds at very low rates, requires little energy, and is markedly enhanced by polybasic compounds.
  • (15) The polybasic macromolecules DEAE-dextran (diethylaminoethyl-dextran, molecular weight 500000) and poly-DL-lysine (molecular weight 30000-70000) were absorbed with a high affinity by spheroplasts of Candida utilis and subsequently, induced lysis.
  • (16) The differences in accumulation levels of Mn2+ and Sr2+ attained after prolonged incubation are completely abolished in cells of which the plasmamembrane has been permeabilized with the polybase DEAE-dextran under isotonic conditions.
  • (17) Adsorption of polybases was rapidly completed even at 0 degrees C; however, with small doses, lysis was poor at 0-12 degrees C and extensive at temperatures above 12 degrees C. This permitted the completion of adsorption before initiating lysis.
  • (18) The results indicate that the phosphorylated form of PGKARKKSSC-geranylgeranyl stoichiometrically interacts with smg p21 GDS, that the presence of the geranylgeranyl moiety is essential for, but not sufficient for, the smg p21 GDS action, and that the presence of the methyl moiety, removal of the three C-terminal amino acids, and the presence of the polybasic amino acids also affect the smg p21 GDS action.
  • (19) Vacuoles isolated from polybase lysed spheroplasts still contained large pools of soluble amino acids, and their ability to transport arginine specifically is a further indication of their functional integrity.
  • (20) It is proposed that the cationic C3a molecule activates rat mast cells in a secretory and nonlytic manner by a nonspecific mechanism similar to that of other polybasic compounds.

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