What's the difference between base and topology?

Base


Definition:

  • (a.) Of little, or less than the usual, height; of low growth; as, base shrubs.
  • (a.) Low in place or position.
  • (a.) Of humble birth; or low degree; lowly; mean.
  • (a.) Illegitimate by birth; bastard.
  • (a.) Of little comparative value, as metal inferior to gold and silver, the precious metals.
  • (a.) Alloyed with inferior metal; debased; as, base coin; base bullion.
  • (a.) Morally low. Hence: Low-minded; unworthy; without dignity of sentiment; ignoble; mean; illiberal; menial; as, a base fellow; base motives; base occupations.
  • (a.) Not classical or correct.
  • (a.) Deep or grave in sound; as, the base tone of a violin.
  • (a.) Not held by honorable service; as, a base estate, one held by services not honorable; held by villenage. Such a tenure is called base, or low, and the tenant, a base tenant.
  • (n.) The bottom of anything, considered as its support, or that on which something rests for support; the foundation; as, the base of a statue.
  • (n.) Fig.: The fundamental or essential part of a thing; the essential principle; a groundwork.
  • (n.) The lower part of a wall, pier, or column, when treated as a separate feature, usually in projection, or especially ornamented.
  • (n.) The lower part of a complete architectural design, as of a monument; also, the lower part of any elaborate piece of furniture or decoration.
  • (n.) That extremity of a leaf, fruit, etc., at which it is attached to its support.
  • (n.) The positive, or non-acid component of a salt; a substance which, combined with an acid, neutralizes the latter and forms a salt; -- applied also to the hydroxides of the positive elements or radicals, and to certain organic bodies resembling them in their property of forming salts with acids.
  • (n.) The chief ingredient in a compound.
  • (n.) A substance used as a mordant.
  • (n.) The exterior side of the polygon, or that imaginary line which connects the salient angles of two adjacent bastions.
  • (n.) The line or surface constituting that part of a figure on which it is supposed to stand.
  • (n.) The number from which a mathematical table is constructed; as, the base of a system of logarithms.
  • (n.) A low, or deep, sound. (Mus.) (a) The lowest part; the deepest male voice. (b) One who sings, or the instrument which plays, base.
  • (n.) A place or tract of country, protected by fortifications, or by natural advantages, from which the operations of an army proceed, forward movements are made, supplies are furnished, etc.
  • (n.) The smallest kind of cannon.
  • (n.) That part of an organ by which it is attached to another more central organ.
  • (n.) The basal plane of a crystal.
  • (n.) The ground mass of a rock, especially if not distinctly crystalline.
  • (n.) The lower part of the field. See Escutcheon.
  • (n.) The housing of a horse.
  • (n.) A kind of skirt ( often of velvet or brocade, but sometimes of mailed armor) which hung from the middle to about the knees, or lower.
  • (n.) The lower part of a robe or petticoat.
  • (n.) An apron.
  • (n.) The point or line from which a start is made; a starting place or a goal in various games.
  • (n.) A line in a survey which, being accurately determined in length and position, serves as the origin from which to compute the distances and positions of any points or objects connected with it by a system of triangles.
  • (n.) A rustic play; -- called also prisoner's base, prison base, or bars.
  • (n.) Any one of the four bounds which mark the circuit of the infield.
  • (n.) To put on a base or basis; to lay the foundation of; to found, as an argument or conclusion; -- used with on or upon.
  • (a.) To abase; to let, or cast, down; to lower.
  • (a.) To reduce the value of; to debase.

Example Sentences:

  • (1) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
  • (2) However, CT will be insensitive in the detection of the more cephalic proximal lesions, especially those in the brain stem, basal cisterns, and skull base.
  • (3) Recently, the validity of the American Thoracic Society (ATS) standards for selection of spirometric test results has been questioned based on the finding of inverse dependence of FEV1 on effort.
  • (4) The omission of Crossrail 2 from the Conservative manifesto , in which other infrastructure projects were listed, was the clearest sign yet that there is little appetite in a Theresa May government for another London-based scheme.
  • (5) Squadron Leader Kevin Harris, commander of the Merlins at Camp Bastion, the main British base in Helmand, praised the crews, adding: "The Merlins will undergo an extensive programme of maintenance and cleaning before being packed up, ensuring they return to the UK in good order."
  • (6) The analysis is based on the personal experience of the authors with 117 cases and the review of 223 cases published in the literature.
  • (7) In the fall of 1975, 1,915 children in grades K through eight began a school-based program of supervised weekly rinsing with 0.2 percent aqueous solution of sodium fluoride in an unfluoridated community in the Finger Lakes area of upstate New York.
  • (8) Basing the prediction of student performance in medical school on intellective-cognitive abilities alone has proved to be more pertinent to academic achievement than to clinical practice.
  • (9) Induction of labor, based upon only (1) a finding of meconium in the amniocentesis group or (2) a positive test in the OCT group, was nearly three times more frequent in the amniocentesis group.
  • (10) Therefore, we have developed a powerful new microcomputer-based system which permits detailed investigations and evaluation of 3-D and 4-D (dynamic 3-D) biomedical images.
  • (11) The distance between the end of fic and the start of pabA was 31 base pairs.
  • (12) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
  • (13) The method is based on two-dimensional scanning photon absorptiometry on the distal part of the forearm.
  • (14) At the fepB operator, a 31 base-pair Fur-protected region was identified, corresponding to positions -19 to +12 with respect to the transcriptional start site.
  • (15) Facebook Twitter Pinterest With a plot based around fake (or real?)
  • (16) Based on our results, we propose the following hypotheses for the neurochemical mechanisms of motion sickness: (1) the histaminergic neuron system is involved in the signs and symptoms of motion sickness, including vomiting; (2) the acetylcholinergic neuron system is involved in the processes of habituation to motion sickness, including neural store mechanisms; and (3) the catecholaminergic neuron system in the brain stem is not related to the development of motion sickness.
  • (17) Based on these results, we concluded that the inhibition of putrefactive anaerobe 3679 by sorbate resulted from a stringent-type regulatory response induced by the protonophoric activity of sorbic acid.
  • (18) Thus, mechanical restitution of the ventricle is a dynamic process that can be assessed using an elastance-based approach in the in situ heart.
  • (19) Mapping of the cross-link position between U2 and U6 RNAs is consistent with base-pairing between the 5' domain of U2 and the 3' end of U6 RNA.
  • (20) Descriptive features of the syndrome in children, adults and adolescents are given based on the respective work of Pine, Masterson and Kernberg.

Topology


Definition:

  • (n.) The art of, or method for, assisting the memory by associating the thing or subject to be remembered with some place.

Example Sentences:

  • (1) The scheme is based on topological information, i.e.
  • (2) These results provide knowledge of the interrelationships between antibiotic and substrate ribosome binding sites which should eventually contribute to a map of ribosomal topology.
  • (3) The conformational properties of these new TASPs are now under investigation, with special emphasis on the relationship between overall conformation and the nature of the topological template.
  • (4) In the context of a simplified diamond lattice model of a six-member, Greek key beta-barrel protein that is closely related in topology to plastocyanin, the nature of the folding and unfolding pathways have been investigated using dynamic Monte Carlo techniques.
  • (5) At the Second Scandinavian Congress on Image Analysis in 1981 Kohonen provided evidence that the map of signals has the same topological order as the map of reactions.
  • (6) Phylogenetic analysis of the aligned sequences by both phenetic and cladistic methods with H. perryi as an outgroup generated one best topology which pairs S. alpinus with S. malma as the most recently derived species, and pairs S. confluentus with S. leucomaenis.
  • (7) Then, a 'hyperstructure matrix' is generated, containing the unique topological relationship between every pair of regions.
  • (8) Linear DNA substrates in which pairing is topologically restricted to a paranemic joint also follow this relationship.
  • (9) The subgroups of carcinoma of the bladder, determined by topology, have markedly different long-term prognoses.
  • (10) The fluorescence properties of Hoechst 33342 (HO 33342) were examined with plasmid pBR322 in the supercoiled (Form I) or relaxed covalently closed circular (Form Io) conformation in order to determine whether qualitative or quantitative differences in fluorescence properties might provide an assay for topological states of DNA.
  • (11) An exhaustive search of all possible trees also supported this topology, although one haplotype had to be eliminated from this analysis to save computer time.
  • (12) This superfamily of proteins is predicted to share the topology of the seven transmembrane helices of bacteriorhodopsin (BR), even though no significant sequence homology had been identified.
  • (13) These data demonstrate the utility of this approach for determining membrane protein topology and extend potential applications to include at least some proteins not normally expressed in E. coli.
  • (14) The unique topology of the products indicates that resolvase fixes the sum of the number of supercoils between recombination sites at synapsis and the number of such supercoils lost or gained during strand exchange.
  • (15) Such explanations are possible because the relatively few structural proteins of the erythrocyte are regularly distributed over the entire cytoplasmic surface of the cell membrane and because the well-understood topological associations of these proteins seem to be stable in comparison with the time required for the cell to change shape.
  • (16) The objectives of the present investigations were to document a composite, new approach for the evaluation of the structure-function dependencies of proteins based on the analysis of the informational content of the primary amino acid sequence as well as the topological and functional regions of a protein.
  • (17) When the input topology is supercoiled, high levels of transcription are observed, whereas input relaxed DNA is transcribed to a much lower extent.
  • (18) It is believed that one or more basic residues at the extreme amino terminus of precursor proteins and the lack of a net positive charge immediately following the signal peptide act as topological determinants that promote the insertion of the signal peptide hydrophobic core into the cytoplasmic membrane of Escherichia coli cells with the correct orientation required to initiate the protein export process.
  • (19) We observe that the effect of osmotic shock is an elevation of superhelical tension; quantitative comparison with changes in plasmid linking number indicates that the alteration in DNA topology is all unconstrained.
  • (20) Anomalous correspondence most probably has its seat where the retinal topology is not exact, i.e., where the binocular receptive fields are very large and encompass the corpus callosum, such as in area 20 or 21.