(n.) A species of pepper (Piper betle), the leaves of which are chewed, with the areca or betel nut and a little shell lime, by the inhabitants of the East Indies. It is a woody climber with ovate many-nerved leaves.
Example Sentences:
(1) Epidemiologists need to conduct studies to determine if there is an increased likelihood of developing cancer in betel chewing pregnant women and OC users due to increased sensitivity of their lymphocytes to genetic damage compared with nonchewing pregnant women and OC users.
(2) Boric acid, propionic acid and potassium metabisulphite were used for the control of aflatoxin B1 on betel nuts.
(3) The results suggest that formation of reactive oxygen species in the presence of NNN may be a key factor in the initiation of oral tumours in tobacco and betel-quid chewers.
(4) Betel leaf extract at the dose levels used in the present study did not affect the body weight gain among rats.
(5) It was found that among the betel chewers as well as the non betels chewers., the highest caries susceptibility was in the age group of 20-34 years.
(6) Powdered slaked lime applied to the chewed Areca nut with Piper betle inflorescence at the corner of the mouth causes the mean pH to rise to 10, at which reactive oxygen species are generated from betel quid ingredients in vitro.
(7) Moreover both the extracts of betel leaf reduce the mutagenicity of benzo(a)pyrene and dimethylbenzanthracene.
(8) Areca cattechu Linn is commonly known as areca nut or betel nut.
(9) The effect of betel leaf extract and some of its constituents, eugenol, hydroxychavicol, beta-carotene and alpha-tocopherol, on benzo[a]pyrene-induced forestomach neoplasia in male Swiss mice was examined.
(10) The frequency of micronucleated cells (MNC) derived from exfoliated human oral mucosal cells has been measured to assess genotoxic damage in chewers of betel quid with tobacco (BQT) and tobacco with lime (T).
(11) Of seven sources, Banarasi betel leaves showed the maximum amounts of beta-carotene and alpha-tocopherol.
(12) Taken together, the observed pathobiological effects of areca-nut extract and certain related compounds in cultured human buccal epithelial cells indicate that these agents may contribute to the oral carcinogenicity associated with chewing betel quid.
(13) The elevation of MEC in Taiwanese, who are at low risk for oral cancer, is relatively small as compared to that found in chewers of Indian betel quids (pan), who show a highly elevated oral cancer risk.
(14) There is a need for more active and culturally appropriate health education programs to help prevent the negative effects of betel-nut chewing.
(15) DMSO extract of a mixture of tobacco and betel nut positively increased the incidence of early malignant changes in the hamster cheek pouch, indicating the enhancing effect of betel nut in carcinogenesis.
(16) A link between the generation of areca nut-related N-nitrosamines in the saliva, the induction of genotoxic damage in the oral mucosa, as judged by an increase in micronucleated exfoliated cells (MEC), and a low incidence of oral cancer was studied in 2 population groups characterized by their habit of chewing quids without tobacco: Guamanians, who chew areca nuts (Areca catechu) with or without the addition of betel leaf (Piper betle); Taiwanese, who use areca nut, betel leaf or inference and slaked lime.
(17) In addition, she had discontinued chewing betel nut that was used daily by virtually all of her fellow islanders on Yap.
(18) Arecoline, a major betel nut alkaloid, was tested for its effectiveness in inducing micronuclei in fetal mouse blood after transplacental exposure late in the gestation period.
(19) "Municipal officers used to come and demand bribes every month from all the street shops and vendors; I would curse them under my breath but used to pay," said Tara Kant Jha, 46, a street vendor who sells cigarettes and betel leaves – used like chewing tobacco.
(20) (3) Formation of endogenous NOC was assessed by the NPRO test in: (i) subjects living in high- and low-incidence areas for stomach cancer in northern Japan, Costa Rica and Poland; (ii) subjects with different habits of betel-quid chewing and tobacco use; (iii) patients with urinary bladder infections; and (iv) subjects infested with liver fluke in Thailand.
Combination
Definition:
(n.) The act or process of combining or uniting persons and things.
(n.) The result of combining or uniting; union of persons or things; esp. a union or alliance of persons or states to effect some purpose; -- usually in a bad sense.
(n.) The act or process of uniting by chemical affinity, by which substances unite with each other in definite proportions by weight to form distinct compounds.
(n.) The different arrangements of a number of objects, as letters, into groups.
Example Sentences:
(1) From 1982 to 1989, bronchoplasty or segmental bronchoplasty and pulmonary arterioplasty in combination with lobectomy and segmentectomy were performed for 9 patients with central type lung carcinoma.
(2) Combinations of maximum amounts of glucagon and the cyclic nucleotide did not produce a greater effect than either agent alone.
(3) Combination therapy was most effective in patients receiving HCTZ prior to enalapril.
(4) Lucy and Ed will combine coverage of hard and breaking news with a commitment to investigative journalism, which their track record so clearly demonstrates”.
(5) The combined immediate and delayed responses to fleas in the dog are as observed by other investigators in man and guinea pigs.
(6) Simplicity, high capacity, low cost and label stability, combined with relatively high clinical sensitivity make the method suitable for cost effective screening of large numbers of samples.
(7) Recently, it has been shown that radiation therapy, alone or combined with chemotherapy, can be successful.
(8) More than 2 months after the combined treatment were required for the suppression.
(9) By combined histologic and cytologic examinations, the overall diagnostic rate was raised to 87.7%.
(10) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(11) The combined analysis of pathogenesis and genetics associated with the salmonella virulence plasmids may identify new systems of bacterial virulence and the genetic basis for this virulence.
(12) Multiple overlapping thin 3D slab acquisition is presented as a magnitude contrast (time of flight) technique which combines advantages from multiple thin slice 2D and direct 3D volume acquisitions to obtain high-resolution cross-sectional images of vessel detail.
(13) Handing Greater Manchester’s £6bn health and social care budget over to the city’s combined authority is the most exciting experiment in local government and the health service in decades – but the risks are huge.
(14) Classical treatment combining artificial delivery or uterine manual evacuation-oxytocics led to the arrest of bleeding in 73 cases.
(15) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(16) When the data correlating DHT with protein synthesis using both labelling techniques were combined, the curves were parallel and a strong correlation was noted between DHT and protein synthesis over a wide range of values (P less than 0.001).
(17) Infection with opportunistic organisms, either singly or in combination, is known to occur in immunocompromised patients.
(18) Side effect incidence in patients treated with the paracetamol-sobrerol combination (3.7%) was significantly lower than that observed in subjects treated with paracetamol (6.1% - P less than 0.01), salicylics (25.1% - P less than 0.001), pyrazolics (12.6% - P less than 0.001), propionics (20.3%, P less than 0.001) or other antipyretics (17.9% - P less than 0.001).
(19) Because of the small number of patients reported in the world literature and lack of controlled studies, the treatment of small cell carcinoma of the larynx remains controversial; this retrospective analysis suggests that combination chemotherapy plus radiation offers the best chance for cure.
(20) Because it has been suggested that the lathyrogen, BAPN, may stimulate the release of proteases, the protease inhibitors Trasylol and epsilon-aminocaproic acid (EACA) were given alone or in combination to BAPN-treated rats.