(v. t.) To tie, or confine with a cord, band, ligature, chain, etc.; to fetter; to make fast; as, to bind grain in bundles; to bind a prisoner.
(v. t.) To confine, restrain, or hold by physical force or influence of any kind; as, attraction binds the planets to the sun; frost binds the earth, or the streams.
(v. t.) To cover, as with a bandage; to bandage or dress; -- sometimes with up; as, to bind up a wound.
(v. t.) To make fast ( a thing) about or upon something, as by tying; to encircle with something; as, to bind a belt about one; to bind a compress upon a part.
(v. t.) To prevent or restrain from customary or natural action; as, certain drugs bind the bowels.
(v. t.) To protect or strengthen by a band or binding, as the edge of a carpet or garment.
(v. t.) To sew or fasten together, and inclose in a cover; as, to bind a book.
(v. t.) Fig.: To oblige, restrain, or hold, by authority, law, duty, promise, vow, affection, or other moral tie; as, to bind the conscience; to bind by kindness; bound by affection; commerce binds nations to each other.
(v. t.) To bring (any one) under definite legal obligations; esp. under the obligation of a bond or covenant.
(v. t.) To place under legal obligation to serve; to indenture; as, to bind an apprentice; -- sometimes with out; as, bound out to service.
(v. i.) To tie; to confine by any ligature.
(v. i.) To contract; to grow hard or stiff; to cohere or stick together in a mass; as, clay binds by heat.
(v. i.) To be restrained from motion, or from customary or natural action, as by friction.
(v. i.) To exert a binding or restraining influence.
(n.) That which binds or ties.
(n.) Any twining or climbing plant or stem, esp. a hop vine; a bine.
(n.) Indurated clay, when much mixed with the oxide of iron.
(n.) A ligature or tie for grouping notes.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(3) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(4) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(5) Power urges the security council to "take the kind of credible, binding action warranted."
(6) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(7) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(8) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(9) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(10) Theoretical computations are performed of the intercalative binding of the neocarzinostatin chromophore (NCS) with the double-stranded oligonucleotides d(CGCG)2, d(GCGC)2, d(TATA)2 and d(ATAT)2.
(11) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(12) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(15) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(16) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(17) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(18) The transported pIgA was functional, as evidenced by its ability to bind to virus in an ELISA assay and to protect nonimmune mice against intranasal infection with H1N1 but not H3N2 influenza virus.
(19) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(20) Binding data for both ligands to the enzyme yielded nonlinear Scatchard plots that analyze in terms of four negatively cooperative binding sites per enzyme tetramer.
Tie
Definition:
(v. t.) A knot; a fastening.
(v. t.) A bond; an obligation, moral or legal; as, the sacred ties of friendship or of duty; the ties of allegiance.
(v. t.) A knot of hair, as at the back of a wig.
(v. t.) An equality in numbers, as of votes, scores, etc., which prevents either party from being victorious; equality in any contest, as a race.
(v. t.) A beam or rod for holding two parts together; in railways, one of the transverse timbers which support the track and keep it in place.
(v. t.) A line, usually straight, drawn across the stems of notes, or a curved line written over or under the notes, signifying that they are to be slurred, or closely united in the performance, or that two notes of the same pitch are to be sounded as one; a bind; a ligature.
(v. t.) Low shoes fastened with lacings.
(v. t.) To fasten with a band or cord and knot; to bind.
(v. t.) To form, as a knot, by interlacing or complicating a cord; also, to interlace, or form a knot in; as, to tie a cord to a tree; to knit; to knot.
(v. t.) To unite firmly; to fasten; to hold.
(v. t.) To hold or constrain by authority or moral influence, as by knotted cords; to oblige; to constrain; to restrain; to confine.
(v. t.) To unite, as notes, by a cross line, or by a curved line, or slur, drawn over or under them.
(v. t.) To make an equal score with, in a contest; to be even with.
(v. i.) To make a tie; to make an equal score.
Example Sentences:
(1) Behind her balcony, decorated with a flourishing pothos plant and a monarch butterfly chrysalis tied to a succulent with dental floss, sits the university’s power plant.
(2) Theresa May signals support for UK-EU membership deal Read more Faull’s fix, largely accepted by Britain, also ties the hands of national governments.
(3) The quantity of social ties, the quality of relationships as modified by type of intimate, and the baseline level of symptoms measured five years earlier were significant predictors of psychosomatic symptoms among this sample of women.
(4) They are just literally lying.” In August Microsoft severed its ties, saying Alec’s stance on climate change and several other issues “conflicted directly with Microsoft’s values”.
(5) There is a gradual loosening of the adolescent's emotional dependence on her parents and a transfer of dependency ties to peers.
(6) We have reported on a simple and secure method of tying up hair during transplantation surgery for alopecia.
(7) Maybe it’s because they are skulking, sedentary creatures, tied to their post; the theatre critic isn’t going anywhere other than the stalls, and then back home to write.
(8) Beijing has no interest in seeing strained ties affecting development plans either.” The Moranbong band was founded by Kim Jong-un , with each member reportedly selected by a leader eager to make his mark on the cultural scene.
(9) Two years ago I met a wonderful man and we now feel it’s time to tie the knot.
(10) The glory lay in the defiance, although the outcome of the tie scarcely looks promising for Arsenal when the return at Camp Nou next Tuesday is borne in mind.
(11) Alec played a role in the resignation of the UK defence secretary Liam Fox last year over his close ties to his friend Adam Werritty.
(12) The Dodgers and Braves are tied 1-1 in the third inning and the Detroit Tigers and Oakland A's ALDS will start at 9:37pm EST.
(13) And if that ties up with one another then Oscar has got a major problem."
(14) Los Angeles were relentless in their vicious pursuit of a game-tying goal on Wednesday, bidding to send Game 4 into overtime.
(15) "This is the guy we've all seen in Borders or HMV on a Friday afternoon, possibly after a drink or two, tie slightly undone, buying two CDs, a DVD and maybe a book - fifty quid's worth - and frantically computing how he's going to convince his partner that this is a really, really worthwhile investment."
(16) The levy would also confirm the dramatically changing nature of Pakistan's ties with its western partners, from a strategic alliance to a transactional relationship, with deep suspicions on both sides.
(17) Trade unions criticised the corporation’s 1% offer, tied to a minimum of just £390, for those staff earning under £50,000, calling it “completely unacceptable” .
(18) Unlike most CDU politicians, he keeps close ties to the British Conservatives despite their differences on Europe .
(19) Last week, the army major who ordered Dar to be tied to the vehicle was awarded a commendation for his counter-insurgency work in the region.
(20) He added, however, that the US would "remain the world's leading military and economic power for the next two to three decades" and he ruled out a radical shift in bilateral ties.