(n.) An invitation to engage in a contest or controversy of any kind; a defiance; specifically, a summons to fight a duel; also, the letter or message conveying the summons.
(n.) The act of a sentry in halting any one who appears at his post, and demanding the countersign.
(n.) A claim or demand.
(n.) The opening and crying of hounds at first finding the scent of their game.
(n.) An exception to a juror or to a member of a court martial, coupled with a demand that he should be held incompetent to act; the claim of a party that a certain person or persons shall not sit in trial upon him or his cause.
(n.) An exception to a person as not legally qualified to vote. The challenge must be made when the ballot is offered.
(n.) To call to a contest of any kind; to call to answer; to defy.
(n.) To call, invite, or summon to answer for an offense by personal combat.
(n.) To claim as due; to demand as a right.
(n.) To censure; to blame.
(n.) To question or demand the countersign from (one who attempts to pass the lines); as, the sentinel challenged us, with "Who comes there?"
(n.) To take exception to; question; as, to challenge the accuracy of a statement or of a quotation.
(n.) To object to or take exception to, as to a juror, or member of a court.
(n.) To object to the reception of the vote of, as on the ground that the person in not qualified as a voter.
(v. i.) To assert a right; to claim a place.
Example Sentences:
(1) Bronchial challenge caused an immediate asthmatic response.
(2) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(3) This frees the student to experience the excitement and challenge of learning and the joy of helping people.
(4) The degree of increase in Meth responsiveness elicited by the initial provocation is a major factor in determining the airway response to a subsequent HS challenge.
(5) Intranasal challenge of allergic subjects with the allergen to which they are sensitive rapidly produces sneezing, rhinorrhea, and airway obstruction.
(6) Matthias Müller, VW’s chief executive, said: “In light of the wide range of challenges we are currently facing, we are satisfied overall with the start we have made to what will undoubtedly be a demanding fiscal year 2016.
(7) In 1935, Einstein challenged the prevailing interpretation of quantum theory.
(8) A shrinking populace is perhaps a greater challenge than any problems with Russia.
(9) Intraperitoneal injection of indomethacin to pretreated animals resulted in increased levels of IL-1 and TNF and decreased levels of PGE2 following challenge with E. coli.
(10) Think of Nelson Mandela – there is a determination, an unwillingness to bend in the face of challenges, that earns you respect and makes people look to you for guidance.
(11) The children's pulse, pulse rate variability, and blood pressure were then measured at rest and during a challenging situation.
(12) At first it looked as though the winger might have shown too much of the ball to the defence, yet he managed to gain a crucial last touch to nudge it past Phil Jones and into the path of Jerome, who slipped Chris Smalling’s attempt at a covering tackle and held off Michael Carrick’s challenge to place a shot past an exposed De Gea.
(13) The results support the notion that mediator lymphocytes circulate in tumor immunized rats in a noncytotoxic state, specifically recognize tumor cells at a challenge site, and mediate induction of effector cells locally.
(14) The role of blood acetylcholinesterase in moderating the effects of organophosphate challenge in rats was tested.
(15) In the first trial to investigate the effect of tick control, significant improvements in liveweight gain (LWG) occurred only in periods of medium to high challenge with adult Amblyomma variegatum.
(16) The SNT and the I-ELISA indicated that the pigs responded to vaccination and challenge.
(17) When caffeine evokes a contraction, and only then, crayfish muscle fibers become refractory to a second challenge with caffeine for up to 20 min in the standard saline (5 mM K(o)).
(18) This observation seriously challenges the hypothesis that SCE cancellation results as a consequence of persistence of the lesions induced by these agents.
(19) Injection of about four ImD 50 of vaccine intracerebrally produced a local immunity, resulting in an immediate kill of challenge organisms given 14 days later.
(20) There was no correlation between anti-TNP-precipitating antibody titer after sensitization and the ability to respond to challenge by hapten-heterologous carrier.
Discreet
Definition:
(superl.) Possessed of discernment, especially in avoiding error or evil, and in the adaptation of means to ends; prudent; sagacious; judicious; not rash or heedless; cautious.
(superl.) Differing; distinct.
Example Sentences:
(1) By indirect immunofluorescence, fibronectin is seen as arrays of long fibers in fibroblastic ECM, whereas in endothelial ECM, fibronectin is found in discreet foci as short fibers.
(2) MRT proved to the superior to CT. CT demonstrated a discreet temporal lobe lesion in three patients and MRT in four patients.
(3) The best senior staff are discreet, disciplined, hard-working, collaborative and almost invisible.
(4) Like his wind turbine though, discreetly taken down some months later, many people are now concluding that Cameron's promise to lead the " greenest government ever " was little more than a fraudulent gimmick, a PR stunt from a man schooled in the PR industry.
(5) The application of these principles and the use of specific treatment modalities to manage the discreet manifestations of dry eye syndrome can lead to successful management in the majority of cases, with the preservation of useful vision and the relief of symptoms.
(6) Out of 80 preschool children, 8% of them had clinically evident signs of a possible cortical lesion, which were discreet and regarded the visuomotor, in other words visuoconstructive functions.
(7) Six royal aides and lawyers were seen at one hearing discreetly monitoring the arguments.
(8) Sampson became the discreet, muttering centre of a web, connected by telephone and letter, telegram and fax, to an astounding cast of world leaders and commentarians, film stars and novelists.
(9) Normally, its diplomats try to maintain as low a profile as possible, conducting business through discreet lunches and dinners rather than mounting such high-profile lobbying exercises.
(10) Still, Suleimani was discreetly involved in negotiations with the US after the September 11 attacks, when Iran offered help to US forces in Afghanistan – until George W Bush included Tehran in "the axis of evil".
(11) Unlike more discreet foreign envoys in London, the ambassador is not afraid to state his views publicly and forcefully.
(12) folds up its comedy deckchair, presses mute on the trombones and drapes a hand towel discreetly over Mark's crotch.
(13) Using skills acquired in his first job with the accountancy giant PricewaterhouseCoopers and his second, buying and selling companies for JP Morgan, he minted a commercial model from the calm opulence of United's discreet Mayfair office that soon became the envy of the football world.
(14) It feels wrong to call for them to be dropped but Stoke fans discreetly admit that their inability to galumph around the pitch as effectively as before is one of the reasons for the team’s recent vulnerability.
(15) One day after the last day of exposure, the animals were decapitated and steady state concentrations of norepinephrine (NE), dopamine (DA), serotonin (5-HT), 3-methoxy-4-hydroxy-mandelic acid (VMA), 3-methoxy-4-hydroxyphenyl glycol (MOPEG), dihydroxphenylacetic acid (DOPAC), and 5-hydroxyindoleacetic acid (5-HIAA) were determined in six discreet brain regions using electrochemical high-performance liquid chromatography.
(16) One of these approaches, the neurobehavioral model of cocaine dependency treatment establishes a clear timetable for cocaine recovery and focusses attention on four discreet areas of functioning.
(17) This is also true for discreet and partial ossification defects which are not visible on conventional x-rays and are described here for the first time.
(18) We piloted the Forget-Me-Not Challenge, encouraging departments to identify patients who have dementia or who are confused by placing a discreet picture of a forget-me-not above their bed.
(19) However, Condé Nast insiders say Greig's resignation is expected within days and the glossy magazine publisher's managing director, Nicolas Coleridge, is understood to be discreetly searching for a replacement Tatler editor.
(20) They pioneered ways of discreetly carving out spaces where other codes apply, protected by cryptic passwords.