(n.) An invitation to engage in a contest or controversy of any kind; a defiance; specifically, a summons to fight a duel; also, the letter or message conveying the summons.
(n.) The act of a sentry in halting any one who appears at his post, and demanding the countersign.
(n.) A claim or demand.
(n.) The opening and crying of hounds at first finding the scent of their game.
(n.) An exception to a juror or to a member of a court martial, coupled with a demand that he should be held incompetent to act; the claim of a party that a certain person or persons shall not sit in trial upon him or his cause.
(n.) An exception to a person as not legally qualified to vote. The challenge must be made when the ballot is offered.
(n.) To call to a contest of any kind; to call to answer; to defy.
(n.) To call, invite, or summon to answer for an offense by personal combat.
(n.) To claim as due; to demand as a right.
(n.) To censure; to blame.
(n.) To question or demand the countersign from (one who attempts to pass the lines); as, the sentinel challenged us, with "Who comes there?"
(n.) To take exception to; question; as, to challenge the accuracy of a statement or of a quotation.
(n.) To object to or take exception to, as to a juror, or member of a court.
(n.) To object to the reception of the vote of, as on the ground that the person in not qualified as a voter.
(v. i.) To assert a right; to claim a place.
Example Sentences:
(1) Bronchial challenge caused an immediate asthmatic response.
(2) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(3) This frees the student to experience the excitement and challenge of learning and the joy of helping people.
(4) The degree of increase in Meth responsiveness elicited by the initial provocation is a major factor in determining the airway response to a subsequent HS challenge.
(5) Intranasal challenge of allergic subjects with the allergen to which they are sensitive rapidly produces sneezing, rhinorrhea, and airway obstruction.
(6) Matthias Müller, VW’s chief executive, said: “In light of the wide range of challenges we are currently facing, we are satisfied overall with the start we have made to what will undoubtedly be a demanding fiscal year 2016.
(7) In 1935, Einstein challenged the prevailing interpretation of quantum theory.
(8) A shrinking populace is perhaps a greater challenge than any problems with Russia.
(9) Intraperitoneal injection of indomethacin to pretreated animals resulted in increased levels of IL-1 and TNF and decreased levels of PGE2 following challenge with E. coli.
(10) Think of Nelson Mandela – there is a determination, an unwillingness to bend in the face of challenges, that earns you respect and makes people look to you for guidance.
(11) The children's pulse, pulse rate variability, and blood pressure were then measured at rest and during a challenging situation.
(12) At first it looked as though the winger might have shown too much of the ball to the defence, yet he managed to gain a crucial last touch to nudge it past Phil Jones and into the path of Jerome, who slipped Chris Smalling’s attempt at a covering tackle and held off Michael Carrick’s challenge to place a shot past an exposed De Gea.
(13) The results support the notion that mediator lymphocytes circulate in tumor immunized rats in a noncytotoxic state, specifically recognize tumor cells at a challenge site, and mediate induction of effector cells locally.
(14) The role of blood acetylcholinesterase in moderating the effects of organophosphate challenge in rats was tested.
(15) In the first trial to investigate the effect of tick control, significant improvements in liveweight gain (LWG) occurred only in periods of medium to high challenge with adult Amblyomma variegatum.
(16) The SNT and the I-ELISA indicated that the pigs responded to vaccination and challenge.
(17) When caffeine evokes a contraction, and only then, crayfish muscle fibers become refractory to a second challenge with caffeine for up to 20 min in the standard saline (5 mM K(o)).
(18) This observation seriously challenges the hypothesis that SCE cancellation results as a consequence of persistence of the lesions induced by these agents.
(19) Injection of about four ImD 50 of vaccine intracerebrally produced a local immunity, resulting in an immediate kill of challenge organisms given 14 days later.
(20) There was no correlation between anti-TNP-precipitating antibody titer after sensitization and the ability to respond to challenge by hapten-heterologous carrier.
Interest
Definition:
(n.) To engage the attention of; to awaken interest in; to excite emotion or passion in, in behalf of a person or thing; as, the subject did not interest him; to interest one in charitable work.
(n.) To be concerned with or engaged in; to affect; to concern; to excite; -- often used impersonally.
(n.) To cause or permit to share.
(n.) Excitement of feeling, whether pleasant or painful, accompanying special attention to some object; concern.
(n.) Participation in advantage, profit, and responsibility; share; portion; part; as, an interest in a brewery; he has parted with his interest in the stocks.
(n.) Advantage, personal or general; good, regarded as a selfish benefit; profit; benefit.
(n.) Premium paid for the use of money, -- usually reckoned as a percentage; as, interest at five per cent per annum on ten thousand dollars.
(n.) Any excess of advantage over and above an exact equivalent for what is given or rendered.
(n.) The persons interested in any particular business or measure, taken collectively; as, the iron interest; the cotton interest.
Example Sentences:
(1) A group of interested medical personnel has been identified which has begun to work together.
(2) Hypothyroidism complicated by spontaneous hyperthyroidism is an interesting but rare occurrence in the spectrum of autoimmune thyroid disorders.
(3) It is quite interesting to analyse which gene of the virus determines the characteristics of the virus.
(4) Another interested party, the University of Miami, had been in talks with the Beckham group over the potential for a shared stadium project.
(5) "Britain needs to be in the room when the euro countries meet," he said, "so that it can influence the argument and ensure that what the 17 do will not damage the market or British interests.
(6) Angle closure glaucoma is a well-known complication of scleral buckling and it is of particular interest when it occurs in eyes with previously normal angles.
(7) Today’s figures tell us little about the timing of the first increase in interest rates, which will depend on bigger picture news on domestic growth, pay trends and perceived downside risks in the global economy,” he said.
(8) To this figure an additional 250,000 older workers must be added, who are no longer registered as unemployed but nevertheless would be interested in finding another job.
(9) Whittingdale also defended the right of MPs to use privilege to speak out on public interest matters.
(10) David Cameron has insisted that membership of the European Union is in Britain's national interest and vital for "millions of jobs and millions of families", as he urged his own backbenchers not to back calls for a referendum on the UK's relationship with Brussels.
(11) But if you want to sustain a long-term relationship, it's important to try to develop other erotic interests and skills, because most partners will expect and demand that.
(12) One of the most interesting aspects of the shadow cabinet elections, not always readily interpreted because of the bizarre process of alliances of convenience, is whether his colleagues are ready to forgive and forget his long years as Brown's representative on earth.
(13) While the majority of EU member states, including the UK, do not have a direct interest in the CAR, or in taking action, the alternative is unthinkable.
(14) And the irony of it is it doesn't interest me at all.
(15) Further exploration of these excretory pathways will provide interesting new insights on the numerous cholestatic and hyperbilirubinemic syndromes that occur in nature.
(16) The information about her father's semi-brainwashing forms an interesting backdrop to Malala's comments when I ask if she ever wonders about the man who tried to kill her on her way back from school that day in October last year, and why his hands were shaking as he held the gun – a detail she has picked up from the girls in the school bus with her at the time; she herself has no memory of the shooting.
(17) Our interest in the role of association brain structures during this behavior is not occasional.
(18) Apart from their pathogenic significance, these results may have some interest for the clinical investigation of patients with joint diseases.
(19) Photograph: AP Reasons for wavering • State relies on coal-fired electricity • Poor prospects for wind power • Conservative Democrat • Represents conservative district in conservative state and was elected on narrow margins Campaign support from fossil fuel interests in 2008 • $93,743 G K Butterfield (North Carolina) GK Butterfield, North Carolina.
(20) Interestingly, different mechanisms of nucleated and non-nucleated TC directed lysis by CD4+ effectors were implied by distinct patterns of sensitivity to cholera toxin (CT) and cyclosporin A (CsA).