(a.) Addicted to crotchets and whims; unreasonable in opinions; crotchety.
(a.) Unsteady; easy to upset; crank.
Example Sentences:
(1) What better symbol of the crankiness of the current protests against economic orthodoxy could David Cameron and Nick Clegg wish for?
(2) ‘You sound like my old, cranky uncle.’ Yes, I am your old, cranky uncle.
(3) Fellow Tory minister Ken Clarke warned the Greeks of "serious consequences" if they voted for "cranky extremists ".
(4) (If he were Malcolm Turnbull, a certain News Corp columnist might write a cranky blog post.)
(5) Dr al-Zayyat has said she could not carry out a full examination because the baby was "miserable and cranky".
(6) The banks have been very cranky about the levy since it leaked yesterday morning.
(7) The justice secretary did not define what he meant by "cranky extremists".
(8) From Kozlova Zaseka station, a cranky old bus takes you up to Tolstoy's house.
(9) She read a lot of science and economics texts - "the most eccentric passage of my life" - and the resulting polemic, about the dumping of nuclear waste, attracted some cranky reviews in the science press, although she says her findings were hardly startling.
(10) She examined Baby P at a child development clinic at St Ann's hospital, in north London , and although she noticed bruises to his body she decided not to carry out a full examination because the child was ''cranky and miserable''.
(11) Tony Abbott spent yesterday looking pretty cranky, particularly when people criticised his proposal to bring back knights and dames .
(12) As recent touring shows of Picasso estate leftovers have demonstrated, the cranky Spaniard was prolific right up until the end of his life, producing works of varying quality.
(13) Reluctant to defend profits made by banks using cheap QE funds, Krugman accused his rival of being a "cranky old man" and using "context and model-free numbers embedded in a rant".
(14) Clarke warned: "If they get a hopeless lot of cranky extremists elected at the next election then they will default on their debt and everybody says they will leave the euro – actually that's quite likely but it doesn't necessarily follow, but they'll default on their debt."
(15) "If they get a hopeless lot of rather cranky extremists elected at the next election then they will default on their debt."
(16) Dr Sabah al-Zayyat notes bruises to his body and face but does not perform a full examination because he is "miserable and cranky".
(17) Greece will face a disastrous future in which it will default on its debts and may be forced to leave the euro if it votes for "cranky extremists" in next month's general election, Ken Clarke has warned.
(18) He thanked journalists – whom he described as a “cranky, cantankerous lot” – for rallying around and pressing for his release.
(19) There probably isn't enough certain scientific evidence yet (how long did it take for Richard Doll to gain a following for his cranky smoking-causes-lung-cancer theories?)
(20) She was “cranky” over the suggestion that the Coalition was reducing payments to patients.
(1) Thus, our study confirmed that male subjects with a history of testicular maldescent have an increased risk for testis cancer, although the magnitude of this risk was lower than suggested previously.
(2) The expression of the mRNA for mouse testicular lactate dehydrogenase (LDH-X) was examined by RNA:cDNA hybridization in situ in the testis and by Northern analyses of meiotic and postmeiotic spermatogenic cell populations.
(3) In contrast, Leydig cells from rat testis contain monooxygenase systems which catalyze the metabolism of PAH, such as DMBA.
(4) Testis MAPs promoted microtubule assembly, but to a lesser degree than brain MAPs.
(5) Comparison of the native and derivatized wheat germ CaMs with native bovine testis CaM indicates that the concentrations of these proteins required for half-maximal stimulation of either erythrocyte membrane Ca2+-ATPase activity or cardiac sarcoplasmic reticulum phosphorylation are very similar.
(6) In an effort to understand the regulation of the onset of testosterone formation in the human fetal testis we measured adenylate cyclase activity in response to hCG stimulation in homogenates of fetal testes obtained from first and second trimester human abortuses.
(7) Gonadoblastoma is an unusual tumor that typically arises in a streak gonad or an abnormal testis of an individual having a Y chromosome.
(8) Immune response in a patient with an in-situ seminoma of the testis was studied.
(9) We conclude that there are high levels of a GHRH-like substance in mature rat testis which is present both at the level of protein product and gene transcript.
(10) Due to low numbers of animals in Replica 1, the reduced Leydig cell volume was not significant after TCDD treatment; however, in Replica 2 there was a dose-dependent reduction (P < 0.01) in volume per testis of Leydig cell cytoplasm, nuclei, or total Leydig cell volume.
(11) The findings also raise the possibility that Prl may play a role in the regulation of testosterone synthesis by the prepubertal testis.
(12) Likewise, [3H]estradiol-receptor complexes from rabbit uterus, Squalus oviduct, or mouse testis bound minimally to Squalus testicular chromatin.
(13) The cells transferred were of three types, normal spleen cells, T cell-enriched spleen and lymph node cells from mice immunized with testis homogenate (TH) in complete Freund's adjuvant (CFA) and given an extract of Bordetella pertussis (BP) and the latter cells activated by in vitro culture with TH antigen for 48 h. Controls were given buffer alone.
(14) Testis weight was decreased to approximately 50% of control after eight weeks of treatment.
(15) There was a testy set of exchanges between the editor and Michael Ellis.
(16) A rare case of a seminoma developing in an atrophic testis is described and the role of testicular atrophy in tumorigenesis is discussed.
(17) The efficacy of combined cytostatic-surgical treatment was evaluated in a prospective study involving 70 patients with germinal tumors of the testis metastasizing into the lungs.
(18) Micrococcal nuclease-digested testis and erythrocyte chromatin was separated into soluble and insoluble fractions.
(19) Specific high affinity saturable binding proteins for oestradiol-17beta have been demonstrated in the cytoplasm of liver, adrenal, pituitary, prostate, epididymis and testis interstitial tissue of the rat.
(20) As for possible causes of reduced Leydig cell activity it was investigated whether the testis was (1) hypoplastic; (2) abnormally fused with the epididymis; (3) located in the abdomen; (4) or UT was associated with hypospadias.