(v. i.) To reach its highest point of altitude; to come to the meridian; to be vertical or directly overhead.
(v. i.) To reach the highest point, as of rank, size, power, numbers, etc.
(a.) Growing upward, as distinguished from a lateral growth; -- applied to the growth of corals.
Example Sentences:
(1) Beckham's decision marks the culmination of a strategy aimed at preserving his brand long after the footballer has faded.
(2) A hypothetical scheme is presented that pursues the processes involved in invasion from the biochemical events generated by attachment of the parasite, to the steric rearrangement of red cell membrane proteins, which culminates in invasion.
(3) He'd later carry this over into Netflix's House Of Cards but before that, TV had already begun to emulate this new, bleak, antiheroic maturity with a cycle of dark, longform, acclaimed dramas, commencing with The Sopranos and culminating in Breaking Bad .
(4) Fox will be accompanied by the sporting director, Hendrik Almstadt, on the back of the 1-1 draw against Wycombe Wanderers in the FA Cup on Saturday, when their failure to beat a League Two side culminated in angry scenes involving the away supporters.
(5) It was found that: the two cell types have the same basal adenylate cyclase activity; prespore cells and prestalk cells are able to relay the extracellular cAMP signal equally well; intact prestalk cells show a threefold higher cAMP phosphodiesterase activity on the cell surface than prespore cells, whereas their cytosolic activity is the same; intact prestalk cells bind three to four times more cAMP than prespore cells; no large differences in cAMP metabolism and detection were observed between cells derived from migrating slugs and culminating aggregates.
(6) Despite a dreadful end to last season, culminating in a 6-1 defeat at Stoke City, FSG are pressing ahead with transfer plans agreed with Rodgers, indicating the manager’s position is safe at the moment.
(7) After standardized observation of mating behavior culminating in ejaculation and a sperm plug, females were allowed to produce litters in undisturbed conditions.
(8) As culmination proceeds, pstA cells transform into pstB cells by activating the ecmB gene as they enter the stalk tube.
(9) Significant numbers of PFC were encountered in the spleen as early as 14 to 18 hours after a single intravenous injection of antigen; after 36 hours the number of PFC rose rapidly and culminated in a maximum population at 5 days, followed by a rapid decline and plateau similar to that for circulating antibody.
(10) Richard Betts, a climate expert at the Meteorological Office and one of about 130 senior authors of Friday's report, said: "This is the culmination of three years' work.
(11) It will feature in meetings of the G8 group of industrialised countries, and the Tokyo international conference on African development, culminating in the Brussels meeting on the new deal for fragile states.
(12) At the culmination of each molt, the larval tobacco hornworm exhibits a pre-ecdysis behavior prior to shedding its old cuticle at ecdysis.
(13) This diplomatic battle culminated last year in the signing of a peace agreement between the rebels and the government which imposed an immediate ceasefire, and was supposed to lead to a government of national unity with Machar once again in the vice-president’s office.
(14) Several lines of experimental evidence suggest that an anterior-posterior gradient of cyclic AMP exists in migrating pseudoplasmodia of the cellular slime mold Dictyostelium discoideum, and that this gradient may be responsible for control of the proportions of stalk and spore cells that form during culmination.
(15) The Hanover action was, she says, the culmination of years of protests and training, the result of tactics that have evolved from action to action.
(16) But relations have steadily improved, as did the Vatican’s influence, culminating in last December’s deal with the US.
(17) His comic adventures are too many to relate, but it may be said that they culminate in a café of 'singing waiters' where, after a wealth of comic 'business' with the tray, he shows his disdain for articulate speech by singing a vividly explicit song in gibberish.
(18) Enzyme activity in developing spore cells increased 10-fold during differentiation from myxamoebae (0 h) to the culmination stage (20 h) and decreased slightly at sorocarp (24 h).
(19) In 1993, at the Branch Davidian religious compound outside Waco, Texas, the Bureau of Alcohol, Tobacco and Firearms didn’t wait for the sect leader, David Koresh, to leave before attempting to arrest him and got into a gun battle that claimed 10 victims and led to a disastrous 51-day siege culminating in dozens more deaths.
(20) We propose a model whereby a protein repressor, under the control of PKA, inhibits precocious induction of stalk cell differentiation by DIF and so regulates the choice between slug migration and culmination.
Enhance
Definition:
(v. t.) To raise or lift up; to exalt.
(v. t.) To advance; to augment; to increase; to heighten; to make more costly or attractive; as, to enhance the price of commodities; to enhance beauty or kindness; hence, also, to render more heinous; to aggravate; as, to enhance crime.
(v. i.) To be raised up; to grow larger; as, a debt enhances rapidly by compound interest.
Example Sentences:
(1) By presenting the case history of a man who successively developed facial and trigeminal neural dysfunction after Mohs chemosurgery of a PCSCC, this paper documents histologically the occurrence of such neural invasion, and illustrates the utility of gadolinium-enhanced magnetic resonance scanning in patient management.
(2) Intrathecal injection of zopiclone potentiated morphine antinociception, while the intracerebroventricular injection of zopiclone failed to enhance morphine antinociception and the intracerebroventricular injection of flumazepil to antagonize the intraperitoneal-zopiclone-induced increase in morphine antinociception.
(3) Elements in the skin therefore seemed to enhance nerve regeneration and function.
(4) These results show that the pathogenic phenotypes of MCF viruses are dissociable from the thymotropic phenotype and depend, at least in part, upon the enhancer sequences.
(5) However, when cross-linked to anti-CD4 or anti-CD8 antibodies a markedly enhanced proliferation of the corresponding subpopulation is observed.
(6) Urinary ANF immunoreactivity was significantly enhanced by candoxatril in both groups (P less than 0.05 and P less than 0.01 in groups 1 and 2, respectively), with a more pronounced effect evident at the higher dose (P less than 0.01).
(7) Because cystine in medium was converted rapidly to cysteine and cysteinyl-NAC in the presence of NAC and given that cysteine has a higher affinity for uptake by EC than cystine, we conclude that the enhanced uptake of radioactivity was in the form of cysteine and at least part of the stimulatory effect of NAC on EC glutathione was due to a formation of cysteine by a mixed disulfide reaction of NAC with cystine similar to that previously reported for Chinese hamster ovarian cells (R. D. Issels et al.
(8) LPS also abrogated the ability of recombinant interferon-gamma (r.IFN-gamma) to enhance macrophage larvicidal activity.
(9) M NET is currently installed in referring physician office sites across the state, with additional physician sites identified and program enhancements under development.
(10) Marked enhancement of IFN-gamma production by T cells was seen in the presence of as little as 0.3% thymic DC.
(11) In the presence of insulin, a qualitatively similar pattern of increasing responses to albumin is observed; the enhancement of each response by insulin is, however, only slightly potentiated by higher albumin concentrations.
(12) Thus adrenaline, via pre- and post-junctional adrenoceptors, may contribute to enhanced vascular smooth muscle contraction, which most likely is sensitized by the elevated intracellular calcium concentration.
(13) Enhanced sensitivity to ITDs should translate to better-defined azimuthal receptive fields, and therefore may be a step toward achieving an optimal representation of azimuth within the auditory pathway.
(14) Nucleotide, which is essential for catalysis, greatly enhances the binding of IpOHA by the reductoisomerase, with NADPH (normally present during the enzyme's rearrangement step, i.e., conversion of a beta-keto acid into an alpha-keto acid, in either the forward or reverse physiological reactions) being more effective than NADP.
(15) To investigate the mechanism of enhanced responsiveness of cholesterol-enriched human platelets, we compared stimulation by surface-membrane-receptor (thrombin) and post-receptor (AlF4-) G-protein-directed pathways.
(16) The cotransfected cells do not grow in soft agar, but show enhanced soft agar growth relative to controls in the presence of added aFGF and heparin.
(17) Furthermore, H-7 enhanced the effect of thrombin on AA release.
(18) Anti-human factor V IgG decreased this enhanced thrombin formation in the presence of platelets, indicating that factor V from platelets was playing an important role in thrombin formation.
(19) Only candidacidal activity was enhanced in FCA-elicited peritoneal macrophages (median C. albicans killed 28% versus 16% for resident peritoneal macrophages, p less than 0.01).
(20) On the other hand, the limbic after-discharges to the hippocampal or amygdaloid stimulation were enhanced by Z. mioga as well as chlorpromazin, but they were inhibited by diazepam.