(v. t.) To cut into jags or points; to slash; as, to dag a garment.
(v. i.) To be misty; to drizzle.
Example Sentences:
(1) In general, optimal DAGAT activity in vitro was observed when long-chain unsaturated acyl-CoAs and diacylglycerols (DAGs) containing long acyl chains were used as substrates for in vitro TAG synthesis (although 1,2-didecanoin was also very effective).
(2) Incubation of microsomes with CDP-DAG of different fatty acid composition results in quantitative and qualitative differences in lysoPI formation.
(3) We now report that two synthetic diacylglycerols (DAG) replicate the stimulatory and inhibitory effects of TPA on frog skin.
(4) The distribution of PKC returned to control values by 24 h. High glucose did not stimulate phosphoinositide hydrolysis, as evidenced by the absence of an increase in the water-soluble inositol phosphates, indicating that DAG was not generated through the action of a phosphoinositide-specific phospholipase C. Cells treated with the cell-permeable DAG analogue 1-oleoyl-2-acetyl glycerol to activate PKC displayed approximately two-fold increases of fibronectin, laminin, and type IV collagen mRNA levels after normalization against actin.
(5) We observed a 30-45% increase in DAG in rat gastrocnemius and diaphragm muscles, 5-15 min after intramuscular or intravenous injections of 1-3 U of insulin per rat, doses which would be expected to activate insulin receptors more fully.
(6) Concomitantly, an increase of inositol phosphates and diacylglycerol (DAG) production was observed.
(7) The accumulation of [14C]C20:4-DAG (lower in ET than in saline-infused rats) was paralleled by a decrease in phosphatidylinositol (PI) labelling, whereas phosphatidic acid showed a transient increase by 5 min in saline- but not in ET-infused rats.
(8) To determine the role of the DAG produced upon bombesin stimulation, we examined the effects of another activator of protein kinase C, the phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA).
(9) It is concluded that carbachol increases [Ca2+]i by facilitating Ca2+ entry through L-type Ca2+ channels via a 1,2-diacylglycerol (DAG)-protein kinase C (PKC)-dependent pathway while quisqualate mobilizes Ca2+ from inositol 1,4,5-trisphosphate (IP3)-sensitive stores.
(10) In order to characterize the properties of the glyceroglycolipid membranes, ESR spectroscopic studies were carried out with an acyl spin-labeled galactosyl ceramide (SL-GC) or a headgroup spin-labeled phospholipid (SL-6-DPPA) in 1,2-dipalmitoyl[beta-cellobiosyl-(1'---3)]glycerol (Cel-DAG) liposomal membranes.
(11) The E. coli dgkA locus which contains the coding sequences for DAG kinase was subcloned into an eukaryotic expression vector, pMT2.
(12) The mean residence time for pharmacologically active molecules in the body was six times shorter for DAG (1.9 hr) than for DBD (11.4 hr).
(13) These data suggest that PKC is a mediator in the generation of DAG.
(14) These results suggest that DAG accumulation is involved in the potentiating effect of A23187 on CCh-stimulated amylase secretion.
(15) It is concluded that insulin-dependent PDH activation, PIG hydrolysis, and IG and DAG generation are mediated by the wild-type but not by the mutated insulin receptor of Val996.
(16) Since most alloantibodies detected only by 2SP-IAT or LISS-DAG were of doubtful clinical significance, and these techniques produced a high number of unwanted positive reactivities, we conclude that 2SP-IAT and LISS-DAG are not appropriate for the pretransfusion screening for unexpected antibodies.
(17) 261, 8597-8600), lipase from Rhizopus arrhizus selectively degraded the 1-acyl-containing species (DAG), but the ether lipid (EAG) was resistant and was identified and quantified after thin layer chromatography separation.
(18) 1-Oleoyl-2-acetylglycerol, a synthetic DAG analog, stimulated endothelial cell DNA synthesis in a concentration-dependent manner.
(19) Whereas DPG and DS are stable at physiological pH, DAG is unstable, undergoing hydrolysis (regeneration of DF) and rearrangement (intramolecular acyl migration to the 2-, 3- and 4-O-acyl-positional isomers).
(20) Addition of PRL to hepatocyte cultures significantly increased [3H]-glycerol incorporation into DAG within 5 minutes which was followed by a loss of cytosolic PKC activity by 10 minutes.
Dork
Definition:
Example Sentences:
(1) You were well served by my distinguished stand-ins, however, and thanks go to them, too, for keeping Dork Talk alive.
(2) Mark Mayer, 38, from Dorking in Surrey, says he faces a similar problem in that his cerebral palsy is not always immediately obvious.
(3) Richard Barklie, 50, from Carrickfergus, Co Antrim, Joshua Parsons, 20, from Dorking, Surrey, and William Simpson, 26, from Ashford, Surrey, were each banned from football matches for five years – the maximum period allowed.
(4) His memoirs are wholly uninformative about his motivations and, though called The Turbulent Years, make the Thatcher governments sound about as turbulent as a drizzly morning in Dorking.
(5) Were these dorks themselves "role models" as broadcasters they might learn to parse syntactically and grammatically correct sentences in comprehensibly accented English.
(6) He claims to have owned the second Macintosh computer bought in the UK (the first apparently went to Douglas Adams) and until last year wrote the Dork Talk technology column for the Guardian.
(7) Sharon Campbell Dorking, Surrey • Ann Farmer ( Letters , 15 July) seems concerned that to debate assisted dying gives the message that we don't value the lives of people with disabilities.
(8) 12.30pm BST Lord Baker of Dorking used his speech to remind the house of the relatively recent introduction of the concept of compassion to prosecutions against those who assist others to die.
(9) Friends Life employs 3,700 people in the UK, with its largest operation in Bristol, and smaller offices in Dorking.
(10) Guardian columnist Polly Toynbee chairs a panel that includes Melissa Benn, Lord Baker of Dorking and Cambridge academic Prof Robin Alexander.
(11) Now 76 and transmuted into Lord Baker of Dorking, he is smiling again as – in his office at 4 Millbank, a few yards from the houses of parliament and with ITN just across the corridor – he outlines his latest vision for English education.
(12) Garrett, with Danielle Molinari and Jo Dorking, meanwhile, live in social housing in Hoxton that has just been bought by a consortium part-owned by Conservative MP Richard Benyon: rents are expected to go up to market rates of £400-£600 a week.
(13) Then there is the mystery of Halina Żaboklicka, a Polish woman whose treasured letters were found in the pub’s old barn during a clear-out in 1995 by the then owners Jo Dorkings and Joe Stephens.
(14) After allowance for age, sex, social class, and severity of symptoms, subjects in the northern towns of Arbroath and Peterlee who had suffered from low back pain in the past year were three to four times as likely to have consulted their doctor about the problem as those living in the southern towns of St Austell and Dorking.