(a.) Wanting in something; incomplete; lacking a part; deficient; imperfect; faulty; -- applied either to natural or moral qualities; as, a defective limb; defective timber; a defective copy or account; a defective character; defective rules.
(a.) Lacking some of the usual forms of declension or conjugation; as, a defective noun or verb.
Example Sentences:
(1) We have cloned the phr gene that encodes DNA photolyase from Salmonella typhimurium by in vivo complementation of Escherichia coli phr gene defect.
(2) Cor triatriatum (CT) is a rare congenital defect, surgically correctable, and sometimes difficult to diagnose by cardiac catheterization.
(3) Sixteen patients (27%) manifested anomalies of the urinary tract: 12 had markedly altered kidneys, 8 of which were unilateral and ipsilateral to the diaphragmatic defect.
(4) Furthermore echography revealed a collateral subperiosteal edema and a moderate thickening of extraocular muscles and bone periostitis, a massive swelling of muscles and bone defects in subperiosteal abscesses as well as encapsulated abscesses of the orbit and a concomitant retrobulbar neuritis in orbital cellulitis.
(5) Seven males have been observed carrying both inherited tritan and red-green defects.
(6) Mechanisms by which a defect in the synthesis of dolichol-oligosaccharides might alter the degree of beta-1,6 branching in N-linked carbohydrates are discussed.
(7) Both Types I and II collagen are important constituents of the affected tissues, and thus defective collagens are reasonable candidates for the primary abnormality in adolescent idiopathic scoliosis (AIS).
(8) Ventricular septal defect types were perimembranous (six), malalignment (seven), supracristal (three), midmuscular (one), and inlet (one).
(9) Defects of several membrane proteins were found with sodium dodecyl sulfate--polyacrylamide gel electrophoresis.
(10) After early repair of congenital cardiovascular defects, such as coarctation of the aorta, late stenosis may become a problem.
(11) The association of these defects of teeth and bone was found to be transmitted as an autosomal dominant trait over four generations.
(12) They presented their clinical observations on 4 brothers from the 'G Family' who shared a constellation of findings with a generalised tendency to midline defects.
(13) Distant ischemia was distinguished from peri-infarctional ischemia by the presence of transient thallium defects in, or slow thallium washout from myocardium not supplied by the infarct-related coronary artery.
(14) A distally based posterior tibial artery adipofascial flap with skin graft was used for the reconstruction of soft tissue defects over the Achilles tendon in three cases and over the heel in three cases.
(15) In the case with a more distally situated VSD, the bundle branches skirted the anterior and distal walls of the defect.
(16) Both models showed the expected wound-healing defects of the diabetic rats.
(17) Intercistronic complementation of these mutants with pm1493 and dl121, two SV40 mutants that are defective in agnoprotein but encode wild-type T antigen, results in an increased synthesis of agnoprotein in the infected cells.
(18) Cells defective in gpa2 fail to produce cAMP in response to glucose stimulation.
(20) This paper reports on observations of five families suffering from distinct thrombophilia due to a protein C defect.
Deficiency
Definition:
(n.) The state of being deficient; inadequacy; want; failure; imperfection; shortcoming; defect.
Example Sentences:
(1) The goals of treatment are the restoration of normal gut peristalsis and the correction of nutritional deficiencies.
(2) These deficiencies in the data compromise HIV surveillance based on diagnostic testing, and supplementary bias-free data are needed.
(3) Congenitally deficient plasmas were used as the substrate for the measurement of procoagulant activities in a one-stage clotting assay.
(4) In contrast, idiopathic GH deficient girls have an onset of puberty and PHV nearer to a normal chronological age and at an early bone age.
(5) The ACTH deficiency recovered spontaneously, with normal cortisol responses to depot Synacthen (greater than 1380 at 6 h) and hypoglycemia (peak, 590) 14 and 18 months postpartum, respectively.
(6) One hundred and twelve dogs, including twenty C3-deficient dogs, were studied over a period of 6 years.
(7) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(8) Paired tolbutamide and glucose infusions using a square wave technique demonstrated that although early phase insulin secretion is dimished in the fetus, this is not due to an absolute deficiency of stored insulin.
(9) A significant association between G6PD deficiency and hemoglobin S correlated with previous studies on similar samples from the general population.
(10) We describe 10 patients with cerebral venous thrombosis: two had protein S deficiency, one had protein C deficiency, one was in early pregnancy, and there was a single case of each of the following: dural arteriovenous malformation, intracerebral arteriovenous malformation, bilateral glomus tumours, systemic lupus erythematosus, Wegener's granulomatosis, non-Hodgkin's lymphoma.
(11) A newborn presenting with persistent umbilical stump bleeding should be screened for factor XIII deficiency when routine coagulation tests prove normal.
(12) Recognition of this deficiency in our knowledge spurred a belated explosion of research that began with an exploration of the fine structure of the mesothelium.
(13) C. parasitica mutant strains deficient in the production of endothiapepsin (eapA-) were constructed using a gene-replacement strategy.
(14) Clinicians should be aware of this new and unusual association of a cerebral glioma and acquired immune deficiency syndrome.
(15) We have previously reported the isolation of a genomic clone encoding human liver-specific peroxisomal alanine:glyoxylate aminotransferase (AGT, EC 2.6.1.44), the deficient enzyme in primary hyperoxaluria type 1 (PH1) (P. E. Purdue, Y. Takada, and C. J. Danpure, J.
(16) Natural killer (NK) cell activity was assessed in the peripheral blood of 20 patients with growth hormone (GH) deficiency due to a hypothalamic deficit of GH-releasing hormone (GHRH).
(17) The results show that of 543 subjects with AA haemoglobin, 106 (19.5%) were G-6-PD deficient and of 93 individuals with AS haemoglobin 13 (14.0%).
(18) Basal plasma levels of oxytocin were found to be low in sodium-deficient adrenalectomized rats and in intact animals treated daily with desoxycorticosterone acetate, both of which groups drank large amounts of NaCl solution, whereas basal plasma levels of arginine vasopressin were neither stimulated nor suppressed.
(19) ACTH also suppressed aldosterone biosynthesis in rats kept on a sodium-deficient diet.
(20) The duodenal mucosa of genotypically normal iron replete and iron deficient mice and mice with sex-linked (sla) and microcytic anemias (mk) was examined for the presence of iron-binding proteins.