(v. i.) To be hopeless; to have no hope; to give up all hope or expectation; -- often with of.
(v. t.) To give up as beyond hope or expectation; to despair of.
(v. t.) To cause to despair.
(n.) Loss of hope; utter hopelessness; complete despondency.
(n.) That which is despaired of.
Example Sentences:
(1) Crushing their dream of denying healthcare to millions of people will put them on that road to despair.
(2) It was the ease with which minor debt could slide into a tangle of hunger and despair.
(3) The behavioural despair test is a good complement for screening except for drugs having a beta-agonist activity, it appears that this test is dependent on functional relationships between alpha 2 and serotonergic systems.
(4) It became his task to use his literary art in an opposite way to Hesse, even though he despaired of what literature might achieve or of the capacity of rich Europeans to change.
(5) He has his job to do and he has to do it the way he thinks best.” On Saturday night, in a sign of the growing concern at the top of the party about the affair, one shadow cabinet member told the Observer : “The issue is already echoing back at us on the doorsteps.” At all levels, there was despair that the furore had turned the spotlight on to Labour’s difficulties as a time when the party had hoped to take advantage of the Tories’ second byelection loss at the hands of Ukip.
(6) Many have been driven to a suicidal despair that only those devoid of human empathy can fail to understand.
(7) In recent weeks a number of suicides apparently linked to financial despair have hit the headlines.
(8) "You can get six, seven or eight calls a day, which would add to anyone's despair and depression.
(9) Thus in your own words you have said why it was utterly inappropriate for you to use the platform of a Pac hearing in this way.” He suggested that many professionals were “in despair at the lack of understanding and cheap haranguing which characterise your manner” after a series of hearings at which Hodge has led fierce interrogations of senior business figures and others.
(10) For Foos, arousal often competed with despair and sadness at what he witnessed.
(11) | Hugh Muir Read more Wherever Labour people gather to discuss how to break out of the vice tightening around the party, answers fail amid sighs of utter despair.
(12) The presumed interrelation between early rearing conditions and the neurobiological status of the infant that might lead to increased risk for despair is not understood.
(13) Erik Erikson used the film character of Dr. Borg from Wild Strawberries to flesh out his life cycle conception of ego integrity versus despair in old age.
(14) But the character – compounded of piercing sanity and existential despair, infinite hesitation and impulsive action, self-laceration and observant irony – is so multi-faceted, it is bound to coincide at some point with an actor’s particular gifts.
(15) He is an innately optimistic character as well as a clever one, and a man who needs to persuade his party not to despair.
(16) The present report deals with the effects of CBZ on two animal models of depression, namely the potentiation of amphetamine-induced anorexia, and the behavioral despair model.
(17) That is the secret of his repetitive name (like Nabokov's criminal hero in his novel Despair: Hermann Hermann, a misprint for Mr Man Mr Man).
(18) On the one hand, he genuinely sees himself as the great liberator of the poor, the man who wept at Britain’s modern-day penury on Glasgow’s Easterhouse estate; on the other, he is the champion of policies that have driven some of the poorest people in society into despair.
(19) Ovariectomy changed the swimming time course and increased the rhythmical index of depression without other serious disturbances of the behavioural "despair" test.
(20) I wanted to rediscover my joy in writing, I wanted to leave behind the heaviness and despair of Dead Europe .
Perplexed
Definition:
(imp. & p. p.) of Perplex
(a.) Entangled, involved, or confused; hence, embarrassd; puzzled; doubtful; anxious.
Example Sentences:
(1) Perplexed, from being absorbed into some undateable future world governed by an advanced technology whose capacities have to be learned as one reads.
(2) The sergeant, listening in, was perplexed: "We obviously have, because I can hear you on the radio.
(3) Whether FcR-mediated signaling and receptor-mediated signaling involved in NK activity share specific biochemical intermediates is not known, but the involvement of tyrosine kinase function in the latter means of cytotoxicity may provide novel avenues for understanding the biochemical basis of this perplexing cellular function.
(4) The arteriogram correctly localized the precise site of hemorrhage in this perplexing case, and a complex surgical problem was simplified.
(5) The trauma-ready practice must also be cognizant of the some-times perplexing legal and insurance issues with regard to preventing and treating sport-related injuries.
(6) According to Lukyanov, the Kremlin is “perplexed” by Trump because it’s not clear what his priorities are nor whether he can work with Congress to achieve them.
(7) While treatment of a young woman with a dysgerminoma of 1 ovary is a matter of perplexity, we believe that a unilateral operation should be limited to those women who desire above all earthly things to retain their childbearing capacity.
(8) The most perplexing issues in pediatric dentistry today are related to the management of patients.
(9) "It is perplexing and preposterous to hear human rights complaints from the US, where torture and kidnapping are legal in the 21st century."
(10) It was a wretched goal to concede and the unfortunate truth for Mignolet is that moment reminded us why many Liverpool supporters are perplexed he has been awarded a new five-year contract.
(11) Instead, when we meet her at the beginning of the series, Nyborg is more concerned with moving house – presumably supplying viewers with shots of a variety of stylish new light fittings and perplexing floor plans to obsess over – than a political party with which she is increasingly disillusioned.
(12) I was [looks perplexed]: ‘Where’s the fabulous Madonna ?’ But it was still deeply interesting just to shake this tiny little hand, and say ‘You’re real’, because in the 80s, these people lived on plinths, they never came down to Earth.” This encounter made Patterson realise that celebrity per se didn’t exist.
(13) The implementation of library orientation and bibliographic instruction in health sciences centers presents some interesting as well as perplexing problems.
(14) It is now shown that the perplexity may be due to the possibility that the coenzyme (NAD) required for UDPG-D activity, may be acting as a substrate for a second dehydrogenase, namely xanthine dehydrogenase, which may utilize NAD as its substrate.
(15) Management of the patient with tinnitus is an extremely perplexing problem.
(16) Paul Salveson, author of a new book on the future of the railways, Railpolitik , is equally perplexed.
(17) Prematurity is one of the most perplexing problems in perinatal care.
(18) If chemical weapons were used, the timing of the attack is perplexing, the inspector said.
(19) Perplexing findings of cortical somatosensory evoked potentials (SEP's) for determining the central sulcus during a craniotomy are reported in a case of brain tumor.
(20) As cellular and molecular approaches combine with physiologic techniques, new information will be available to address the clinical issues of luteal dysfunction which perplex us all.