(1) It appears that irrespective of the elucidation of the nature of the putative aetiological factor (presumed to be viral) in MS, the arrest and reversal of T cell-related events within the CNS in this devastating condition represent feasible goals and should remain a major target for some time to come.
(2) Samaras said: A "Grexit", as it is called, would be devastating for Greece and detrimental to Europe.
(3) While winds gusting to 170mph caused significant damage, the devastation in areas such as Tacloban – where scenes are reminiscent of the 2004 Indian ocean tsunami – was principally the work of the 6-metre-high storm surge, which carried away even the concrete buildings in which many people sought shelter.
(4) The Financial Services Authority is meant to be the City's watchdog but "devastating" internal documents reveal it has secretly co-ordinated high-level lobbying strategies with the industry it is supposed to police.
(5) The government acknowledged it had been overwhelmed by the devastation from the deadliest quake in Nepal in over 80 years.
(6) Mark Rasch, a cyber crime expert quoted by the FT, meanwhile said recent events have been “a serious and devastating attack to [Sony’s] reputation and image”, and his opinion is played out by a new YouGov poll into the public perception of Sony’s brand.
(7) "When people don't feel they have a reason to stay out of trouble, the consequences for communities can be devastating – as we saw last August," said Darra Singh, chair of the panel.
(8) Newcastle United are “devastated” by their relegation from the Premier League, according to the club’s managing director Lee Charnley.
(9) In order to reduce the devasting effects of enteric diseases among children born to mothers in tropical countries of Africa and Asia, it is imperative that all health workers understand the cultural and social perceptions of their clients towards the disease in question.
(10) All the personality, dignity and humanity of a person are devastated by this torture.
(11) Age UK believes McDonald's human rights have been breached and that there could be "extremely adverse and devastating consequences for many thousands of older people if other councils take similar decisions to save money".
(12) And then, as the Guardian revealed at the weekend, there is the potentially devastating effect of the boundary changes, which can’t really be brought in before an early election but will radically tilt the field by 2020.
(13) He said: "[That] could be devastating for the renewables industry.
(14) To say that the loss of BB King is devastating to the blues community is an understatement.
(15) 'Devastated' Peter Greste calls on Egypt's president to pardon trio Read more “It’s ironic that the conviction was for tarnishing Egypt’s reputation when ... this [case] is what’s tarnished Egypt’s image,” Clooney told BBC News.
(16) The report, extracts of which were published by the investigative news website Exaro , is said to include “devastating detail” of the corporation’s “sheer scale of awareness” of the late star’s activities.
(17) Although anterior and posterior traumatic displacement of cervical vertebrae are commonly noted, and the devastating neurological deficits associated with these injuries have been amply defined, lateral displacement with fractures has been rarely recognized, and the clinical significance of this injury has been overlooked.
(18) Bernard Hogan-Howe, the Met commissioner, said a report revealing the undercover officers had spied on the family of murdered teenager Stephen Lawrence was “devastating” for Scotland Yard and “one of the worst days that I have seen as a police officer”.
(19) The case for halting British arms sales to Saudi Arabia has been evident, not only on moral grounds, since civilians started dying in the conflict devastating Yemen.
(20) Devastating neurologic complications can be avoided or alleviated in a great proportion of patients undergoing radiation therapy for cerebral metastases and spinal cord compression.
Disastrous
Definition:
(a.) Full of unpropitious stellar influences; unpropitious; ill-boding.
(a.) Attended with suffering or disaster; very unfortunate; calamitous; ill-fated; as, a disastrous day; a disastrous termination of an undertaking.
Example Sentences:
(1) However, we have observed cracks on the Dacron fibers, fiber fracture, fiber protrusion, and poor attachment to the diaphragm, which can cause potentially disastrous complications.
(2) This proposal is a purely partisan move that will backfire on the government disastrously.” The Green party accused Osborne of making “efforts to limit the democratic scrutiny of his austerity agenda”.
(3) They moved to shore up May’s position after a weekend of damaging leaks and briefings from inside the cabinet, believed to be fuelled by some of those jostling to succeed the prime minister after her disastrous election result.
(4) To leave the Euro, says Clarke, would be "disastrous" for the Greeks.
(5) There are no easy answers to these problems, but we must recognise that a muri approach is potentially disastrous.
(6) Prior planning of the coverage before the excision pays dividends by preventing disastrous complications.
(7) But Frank argues the disastrous attempt at curbing markets through currency reform in 2009 has shown the cost of turning back from change.
(8) Getting them to safety is now vital.” While the EU’s hotspots approach improved the fingerprinting and security vetting of migrants, the auditors said that funding and relocation “bottlenecks” had extended the detention of migrants, with disastrous consequences for children.
(9) He argued that it was vital that we “should give the people of this country a chance to decide”, and that “[the nation was witnessing] a continuation of that old and disastrous system where a few men in charge of the state, wielding the whole force of the state, make secret engagements and secret arrangements, carefully veiled from the knowledge of the people…” This, and a lot more little-known information on the road to the first world war is given in Douglas Newton’s book The Darkest Days .
(10) However, the shadow foreign secretary, Douglas Alexander , is adamant Labour could not afford to spend the first two years of government wrestling with a referendum on Europe, pointing to the energy it had expended on the near-disastrous no campaign for the Scotland independence vote.
(11) The disastrous launches of SimCity and Battlefield 4 , the confining and somewhat invasive nature of the publisher’s Origin digital gaming platform and the voraciously monetised smartphone version of Dungeon Keeper, have kicked further dents in its reputation.
(12) Austin said: "Since the House of Lords judgment, the police have increased their use of the tactic of kettling, with disastrous consequences for the right to peaceful protest and the safety of protesters.
(13) By trading Holiday for Noel, the 76ers are effectively ending the Andrew Bynum experiment after one disastrous year and seem likely to start a rebuilding process.
(14) Casting a vote for any of the alternative party or independent candidates in November could have truly disastrous effects.
(15) If she learns anything from this disastrous outing, I hope itʼs that if sheʼs going to allow the music industry to play her as a sex object, she needs to at least own it.
(16) Mike Griffiths, headteacher at Northampton School for Boys, the first high-performing school to become an academy after Gove became secretary of state for education in May 2010, said the issue would not only have a potentially disastrous effect on pupils who failed to get a necessary C grade in English, but also on those hoping to study at elite institutions who fell short of getting As or A*s. "If you are applying to a Russell Group university, for instance, to study medicine or law, and all the applicants have a string of A*s, they will look back to the GCSEs and see a B in English – and that could decide your fate," he said.
(17) As well as causing a breakdown in trust between the north and the capital, and between communities in the north, caused by the occupation, the conflict has been economically disastrous.
(18) "People forget that I discussed two types of disaster in my book: disastrous developments and disastrous failures to develop."
(19) In 1993, at the Branch Davidian religious compound outside Waco, Texas, the Bureau of Alcohol, Tobacco and Firearms didn’t wait for the sect leader, David Koresh, to leave before attempting to arrest him and got into a gun battle that claimed 10 victims and led to a disastrous 51-day siege culminating in dozens more deaths.
(20) Lord of the Rings made him the doomed anti-hero , he was easily the best thing in the disastrous Troy, giving Odysseus guile, wit and that familiar, rough-edged charm, and he terrified TV viewers as property developer John Dawson in the dark and brilliant Red Riding .