(a.) Hard to do or to make; beset with difficulty; attended with labor, trouble, or pains; not easy; arduous.
(a.) Hard to manage or to please; not easily wrought upon; austere; stubborn; as, a difficult person.
(v. t.) To render difficult; to impede; to perplex.
Example Sentences:
(1) Virtually every developed country has some form of property tax, so the idea that valuing residential property is uniquely difficult, or that it would be widely evaded, is nonsense.
(2) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(3) In practice, however, the necessary dosage is difficult to predict.
(4) Cor triatriatum (CT) is a rare congenital defect, surgically correctable, and sometimes difficult to diagnose by cardiac catheterization.
(5) By drawing from the pathophysiology, this article discusses a multidimensional approach to the treatment of these difficult patients.
(6) Past imaging techniques shown in the courtroom have made the conventional rules of evidence more difficult because of the different informational content and format required for presentation of these data.
(7) The way we are going to pay for that is by making the rules the same for people who go into care homes as for people who get care at their home, and by means-testing the winter fuel payment, which currently isn’t.” Hunt said the plan showed the Conservatives were capable of making difficult choices.
(8) In many cases, physicians seek to protect themselves from involvement with these difficult, highly anxious patients by making a referral to a psychiatrist.
(9) The diagnosis of variant- or Prizmetal-angina is difficult because if insufficient specificity of the tests.
(10) The detection of these antibodies is difficult owing to the lack of standardization and of specificity of the laboratory tests.
(11) It was so difficult to keep a straight face when I was filming a sauna scene with Roy Barraclough, who played the mayor of Blackpool.
(12) That is, he believes, to look at massively difficult, interlocking problems through too narrow a lens.
(13) Conversion of the active-site thiol to thiocyanate makes it more difficult to inactivate the enzyme by treatment with Cd2+.
(14) If they end up going to another club that is difficult to take.
(15) Cigarette consumption has also been greater in urban areas, but it is difficult to estimate how much of the excess it can account for.
(16) The most difficult thing I've dealt with at work is ... the terminal illness of a valued colleague.
(17) In that respect, it's difficult to see Allen's anthem as little more than same old same old, and it's probably why I ultimately feel she misses the mark.
(18) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(19) Extrapolation of gestational age from early crown-rump lengths (CRLs) has been difficult because previously established tables of CRL versus gestational age have contained few measurements at less than seven to eight weeks from the first day of the last menses.
(20) Companies had made investments in certain energy sources, the president said, so change could be “uncomfortable and difficult”.
Formidable
Definition:
(a.) Exciting fear or apprehension; impressing dread; adapted to excite fear and deter from approach, encounter, or undertaking; alarming.
Example Sentences:
(1) This implementation reduced a formidable task to a relatively routine run.
(2) It’s likely Xi’s brand of smart authoritarianism will keep not just his party in power but the whole show on the road If all this were to succeed as intended, western liberal democratic capitalism would have a formidable ideological competitor with worldwide appeal, especially in the developing world.
(3) That led to the second breakthrough, as the once formidable laws of omerta - silence punishable by death - cracked.
(4) "This is a formidable challenge, requiring step changes in the rate at which we improve our energy efficiency and in low-carbon innovation.The Carbon Trust's proposals recognise the need for us to be smarter in focusing our investments, including to help businesses seize the economic opportunities of the transition."
(5) The Fellowship combines the academic rigour of an MBA with the reflective and ideological framework of a wellness retreat in Bali; without the sun and spa treatments, but with the added element of the formidable Dame Mary Marsh, a great example of a woman leading as a former headteacher, charity chief executive, NED and leadership development campaigner.
(6) But it also demonstrated that he remains a formidably well-connected political player.
(7) Since then, Amazon has expanded into other retail categories, such as food, clothing and electricals, and developed a formidable cloud computing service, its own television shows and an electronic personal assistant for people’s homes.
(8) As in their previous home game against Leicester City, Everton equalised swiftly through the formidable Lukaku.
(9) The difficulties encountered in good experimental design in this formidable area, which may account for the paucity of work, are discussed.
(10) Tumor cell heterogeneity is now recognized as the principal cause of treatment failure in cancer, and is a formidable obstacle to effective therapy and to the development of drug delivery systems for selective targeting of antineoplastic agents to tumor cells.
(11) A formidable war chest from decades in various businesses has also helped, but it has come with allegations of corruption dating back to his time as a customs official.
(12) Bacterial endocarditis remains a formidable diagnostic and therapeutic problem for clinicians.
(13) Patients having a double-outlet right ventricle with an unfavorable anatomy for reparative conduit procedure present a formidable surgical challenge.
(14) He has strongly insisted that he acted within the law and has assembled a formidable legal team – part-funded by taxpayer money – to fight the accusations.
(15) As it is, the team were careless with a comfortable lead in Jamaica (but got away with it ), formidable in their movement against an outclassed Panama , and struggled to get going in the heat and altitude of their game against Honduras .
(16) The peptide chemists are facing formidable challenges borne by a continually increasing interest in the pharmaceutical uses of peptides.
(17) Graduate physicians face formidable developmental tasks during residency training as they prepare for their professional careers.
(18) The hectic pace of office practice can make full assessment of the patient difficult and state-of-the-art management a formidable goal.
(19) In classic von Willebrand's disease (vWd), assignment of the heterozygous genotype for genetic studies and diagnosis for clinical purposes (which are not exactly the same) are formidable problems.
(20) "It will be a formidably difficult negotiation," he said.