(n.) The quantity of medicine given, or prescribed to be taken, at one time.
(n.) A sufficient quantity; a portion; as much as one can take, or as falls to one to receive.
(n.) Anything nauseous that one is obliged to take; a disagreeable portion thrust upon one.
(n.) To proportion properly (a medicine), with reference to the patient or the disease; to form into suitable doses.
(n.) To give doses to; to medicine or physic to; to give potions to, constantly and without need.
(n.) To give anything nauseous to.
Example Sentences:
(1) This trend appeared to reverse itself in the low dose animals after 3 hr, whereas in the high dose group, cardiac output continued to decline.
(2) The resulting dose distribution is displayed using traditional 2-dimensional displays or as an isodose surface composited with underlying anatomy and the target volume.
(3) Age difference did not affect the mean dose-effect response.
(4) The rash presented either as a pityriasis rosea-like picture which appeared about three to six months after the onset of treatment in patients taking low doses, or alternatively, as lichenoid plaques which appeared three to six months after commencement of medication in patients taking high doses.
(5) Neutrons induced a dose-dependent cytotoxicity and mutation frequency in the AL cells.
(6) Urinary ANF immunoreactivity was significantly enhanced by candoxatril in both groups (P less than 0.05 and P less than 0.01 in groups 1 and 2, respectively), with a more pronounced effect evident at the higher dose (P less than 0.01).
(7) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(8) The fraction of the viral dose which became cell associated was independent of the incubation temperature and increased with increasing target membrane concentration.
(9) The second group only with Haloperidol (same dose).
(10) The level of gadd45 mRNA increased rapidly after X rays at doses as low as 2 Gy.
(11) The cumulative incidence of grade II and III acute GVHD in the 'low dose' cyclosporin group was 42% compared to 51% in the 'standard dose' group (P = 0.60).
(12) The diffusion of Myocamicin in the prostatic tissue of patients undergoing prostatectomy after a single oral dose of 600 mg has been studied.
(13) In X-irradiated litters, almost invariably, the incidence of anophthalmia was higher in exencephalic than in nonexencephalic embryos and the ratio of these incidences (relative risk) decreased toward 1 with increasing dose.
(14) Similarly, doses of deferoxamine at the time of the study were not different.
(15) A survey carried out two and three years after the launch of the official campaign also showed a reduction in the prevalence of rickets in children taking low dose supplements equivalent to about 2.5 micrograms (100 IU) vitamin D daily.
(16) A quantitative comparison of tissue distribution and excretion of an orally administered sublethal dose of [3H]diacetoxyscirpenol (anguidine) was made in rats and mice 90 min, 24 hr, and 7 days after treatment.
(17) The inhibitory effects were stronger in A549 lung cancer cells than in HEL cells at the same TFP dose.
(18) At the highest dose of chloroquine tested (500 microM), a slightly greater increase in insulin binding and a decrease in insulin degradation were observed in fetal cells as compared with adult cells.
(19) Pituitary weight, mitotic index and chromosomes were studied in male rats following a single or repeated dose of estradiol-benzoate for a total period of 210 days.
(20) Estimates of the risk probability for each dose level and sacrifice time are found utilizing the sample likelihood as the posterior density.
Overdose
Definition:
(v. t.) To dose to excess; to give an overdose, or too many doses, to.
(n.) Too great a dose; an excessive dose.
Example Sentences:
(1) There were two spontaneous abortions, both in the first trimester, which occurred two weeks after the overdose which may be related to the paracetamol.
(2) Toxicity has been reported in the fetus of a woman ingesting a huge overdose of digitoxin; the same result would be anticipated with digoxin poisoning.
(3) The level of prescribing of opioid painkillers – Percocet in Geni’s case – has soared, and with it the incidence of addiction, and addiction’s grim best friend: fatal overdoses.
(4) In another patient, there were symptoms of drug overdose when the contents of the balloon spilled into the intestinal tract.
(5) Rates of past-year heroin abuse or dependence and heroin-related overdose deaths in the United States, 2002–2013.
(6) Two cases of death involving methylenedioxymethamphetamine (MDMA) are reported; one case is a fatal acute overdose and the other is a drug-related death.
(7) Most people choose a method for suicide and repeatedly use the same method (physical versus overdose).
(8) In a two-month period, three patients were admitted to a general hospital because of acetaminophen overdose, suggesting that this problem may occur more commonly than expected.
(9) The clinical efficacy of haemoperfusion in AT overdose despite the high volume of distribution of AT deserves further investigation.
(10) The prompt treatment by IV furosemide may be beneficial in the management of massive digitalis overdose.
(11) Although specific recommendations for calcium dosing in the overdose situation have not been rigorously studied, maintenance of a normal serum ionized calcium concentration is suggested.
(12) Massive LSD overdose in humans is life-threatening and produces striking and distinctive manifestations.
(13) Furthermore, the persistence of glucagon's cardiovascular actions following beta-adrenergic blockade indicates the potential clinical utility of glucagon in reversing the adverse effects of beta-blocker overdoses, and its potential usefulness in treating circulatory shock in "beta-blocked" patients.
(14) On the home front in the US, the war on drugs is unable to prevent record numbers of overdoses and declining life expectancies.
(15) We analyzed trends in prescribing and overdose deaths related to propoxyphene (e.g., Darvon) before and after a 1978-80 informational campaign carried out by the US Food and Drug Administration and the drug's manufacturer through mailed warnings, face-to-face education of prescribers, press releases, and labeling changes.
(16) During the past 10 years, a number of serious poisonings have been attributed to verapamil overdose.
(17) Overdose patients had significantly higher stable and global attributions for negative events than controls, but were no different in attribution for positive events.
(18) The purpose of this study was to isolate significant clinical or demographic findings concerning overdose patients treated during a China White (3-methyl fentanyl) epidemic and compare them with data for all unintentional narcotic overdose patients during a 24-month period.
(19) The reasons behind these rises in fatal overdoses are unclear, but a number of factors may be involved, including: increased heroin availability, higher purity, ageing users and changing consumption patterns, including the use of synthetic opioids and medicines.
(20) However, as the overdoses occurred at weeks 26 and 28 respectively, long after the structural development of these organs, the malformations could not have been caused by the paracetamol.