(1) Similar experimental manipulation has yielded in vitro lines established from avian B-cell lymphomas expressing elevated levels of c-myc or v-rel.
(2) Intestinal dilatation seemed in all cases a response to elevated CO2 only.
(3) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(4) We conclude that chronic emphysema produced in dogs by aerosol administration of papain results in elevated pulmonary artery pressure, which is characterized pathologically by medial hypertrophy of small pulmonary arteries.
(5) Thus adrenaline, via pre- and post-junctional adrenoceptors, may contribute to enhanced vascular smooth muscle contraction, which most likely is sensitized by the elevated intracellular calcium concentration.
(6) The increase in red blood cell mass was associated with an elevation in erythropoietic stimulatory activity in serum, pleural fluid, and tumor-cyst fluid as determined by the exhypoxic polycythemic mouse assay.
(7) Maximal aberration yields were observed for 2,4-diaminotoluene, 2,6-diaminotoluene and cytosine beta-D-arabinofuranoside from 17 to 21 h, eugenol from 15 to 21 h, cadmium sulfate from 15 to 24 h and 2-aminobiphenyl, from 17 to 24 h. For adriamycin at 1 microM, the % aberrant cells remained elevated throughout the period from 9 to 29 h, while small increases at 0.1 microM ADR were found only at 13 and at 25 h. For most chemicals the maximal aberration yield occurred at a different time for each concentration tested.
(8) Hepatic enzyme elevations were more dramatic after blunt trauma, reflecting greater hepatocellular disruption.
(9) The erythrocyte sedimentation rate is almost always markedly elevated.
(10) Total cholesterol levels are elevated, particularly in hypopituitary women.
(11) In experiments performed to determine whether PtdIns(4,5)P2 hydrolysis induced by TRH may have been caused by the elevation of [Ca2+]i, the following results were obtained: the effect of TRH to decrease the level of PtdIns(4,5)P2 was not reproduced by the calcium ionophore A23187 or by membrane depolarization with 50 mM K+; the calcium antagonist TMB-8 did not inhibit the TRH-induced decrease in PtdIns(4,5)P2; and, most importantly, inhibition by EGTA of the elevation of [Ca2+]i did not inhibit the TRH-induced decrease in PtdIns(4,5)P2.
(12) During capillary growth when endothelial cells (EC) undergo extensive proliferation and migration and pericytes are scarce, hyaluronic acid (HA) levels are elevated.
(13) If tracer is introduced into the carotid artery after osmotic treatment, brain uptake is increased by a net factor of 50 (a factor of 70 due to elevation of PA, multiplied by 7 due to infusion by the carotid route) as compared to uptake by normal, untreated brain with infusion into a peripheral vein.
(14) Beta-galactosidase, beta-n-acetyl-hexosaminidase, and alpha-fucosidase were sensitive indicators and were significantly elevated above control values by day 3 at both doses (P < 0.01).
(15) When irradiated circular DNA, previously nicked by T4 endonuclease V, is briefly exposed to elevated temperature, the DAN becomes susceptible to the action of exonuclease V, and pyrimidine dimers are selectively released.
(16) Finally, it could be observed that elevated osmotic pressures reduced the lysis of isolated secretory granules when bicarbonate ions were present in the incubation medium.
(17) Eight other children (20%) had normal or borderline elevation of CPK-MB fraction and EKG abnormalities combined with abnormal echocardiograms or radionuclide angiograms, and were considered to have sustained cardiac concussion.
(18) Increased iron levels in basal ganglia were generally associated with normal or elevated levels of ferritin immunoreactivity, for example, the substantia nigra in PSP and possibly MSA, and in putamen in MSA.
(19) The only localized tumors known to produce elevation of CEA above the levels observed in non malignant diseases are carcinomas of the large bowel and the pancreas.
(20) In neither case has a significant elevation in inherited genetic effects or cancer been detected in the offspring of exposed individuals.
High
Definition:
(v. i.) To hie.
(superl.) Elevated above any starting point of measurement, as a line, or surface; having altitude; lifted up; raised or extended in the direction of the zenith; lofty; tall; as, a high mountain, tower, tree; the sun is high.
(superl.) Regarded as raised up or elevated; distinguished; remarkable; conspicuous; superior; -- used indefinitely or relatively, and often in figurative senses, which are understood from the connection
(superl.) Elevated in character or quality, whether moral or intellectual; preeminent; honorable; as, high aims, or motives.
(superl.) Exalted in social standing or general estimation, or in rank, reputation, office, and the like; dignified; as, she was welcomed in the highest circles.
(superl.) Of noble birth; illustrious; as, of high family.
(superl.) Of great strength, force, importance, and the like; strong; mighty; powerful; violent; sometimes, triumphant; victorious; majestic, etc.; as, a high wind; high passions.
(superl.) Very abstract; difficult to comprehend or surmount; grand; noble.
(superl.) Costly; dear in price; extravagant; as, to hold goods at a high price.
(superl.) Arrogant; lofty; boastful; proud; ostentatious; -- used in a bad sense.
(superl.) Possessing a characteristic quality in a supreme or superior degree; as, high (i. e., intense) heat; high (i. e., full or quite) noon; high (i. e., rich or spicy) seasoning; high (i. e., complete) pleasure; high (i. e., deep or vivid) color; high (i. e., extensive, thorough) scholarship, etc.
(superl.) Strong-scented; slightly tainted; as, epicures do not cook game before it is high.
(superl.) Acute or sharp; -- opposed to grave or low; as, a high note.
(superl.) Made with a high position of some part of the tongue in relation to the palate, as / (/ve), / (f/d). See Guide to Pronunciation, // 10, 11.
(adv.) In a high manner; in a high place; to a great altitude; to a great degree; largely; in a superior manner; eminently; powerfully.
(n.) An elevated place; a superior region; a height; the sky; heaven.
(n.) People of rank or high station; as, high and low.
(n.) The highest card dealt or drawn.
(v. i.) To rise; as, the sun higheth.
Example Sentences:
(1) Cancer patients showed abnormally high plasma free tryptophan levels.
(2) Results by these three assays were also highly reproducible.
(3) This trend appeared to reverse itself in the low dose animals after 3 hr, whereas in the high dose group, cardiac output continued to decline.
(4) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(5) The rash presented either as a pityriasis rosea-like picture which appeared about three to six months after the onset of treatment in patients taking low doses, or alternatively, as lichenoid plaques which appeared three to six months after commencement of medication in patients taking high doses.
(6) The angiographic appearances are highly characteristic and equal in value to a histological diagnosis.
(7) When micF was cloned into a high-copy-number plasmid it repressed ompF gene expression, whereas when cloned into a low-copy-number plasmid it did not.
(8) We also show that proliferation of primary amnion cells is not dependent on a high c-fos expression, suggesting that the function of c-fos is more likely to be associated with other cellular functions in the differentiated amnion cell.
(9) The high amino acid levels in the cells suggest that these cells act as inter-organ transporters and reservoirs of amino acids, they have a different role in their handling and metabolism from those of mammals.
(10) after operation for hip fracture, and merits assessment in other high-risk groups of patients.
(11) Villagers, including one man who has been left disabled and the relatives of six men who were killed, are suing ABG in the UK high court, represented by British law firm Leigh Day, alleging that Tanzanian police officers shot unarmed locals.
(12) PMS is more prevalent among women working outside the home, alcoholics, women of high parity, and women with toxemic tendency; it probably runs in families.
(13) Simplicity, high capacity, low cost and label stability, combined with relatively high clinical sensitivity make the method suitable for cost effective screening of large numbers of samples.
(14) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(15) Five probes of high specificity to individual chromosomes (chromosomes 3, 11, 17, 18 and X) were hybridized in situ to metaphase chromosomes of different individuals.
(16) Morphological alterations in the lungs of pheasants after prolonged high-dosage administration of bleomycin sulfate were studied by light and electron microscopy.
(17) In vitro studies carried out in this Department confirmed the high activity of mecillinam against Salmonella spp.
(18) The high transition enthalpy for kerasin is ascribed to a lesser accommodation of gauche conformers in the hydrocarbon chains just below the transition temperature.
(19) beta-Endorphin blocked the development of fighting responses when a low footshock intensity was used, but facilitated it when a high shock intensity was delivered.
(20) Multiple overlapping thin 3D slab acquisition is presented as a magnitude contrast (time of flight) technique which combines advantages from multiple thin slice 2D and direct 3D volume acquisitions to obtain high-resolution cross-sectional images of vessel detail.