(1) At saturating concentrations of ER, plasmids bearing one, two, and four EREs in tandem bound approximately one, two, and four dimeric ER molecules, respectively.
(2) Interestingly, each of these fragments had a perfect palindromic estrogen responsive element (ERE) (GGT-CANNNTGACC).
(3) These data suggest that flanking DNA sequences may exert a significant effect on the activity of EREs as hormone-dependent transcription activators.
(4) In 11 spontaneously breathing patients with chronic obstructive pulmonary disease (COPD) in acute ventilatory failure, we measured the total inspiratory (WItot) and total resistive (WI + Eres) work rate of breathing, together with lung mechanics (dynamic pulmonary elastance and inspiratory and expiratory pulmonary flow resistance).
(5) This element binds to the estrogen receptor in vitro as assessed by gel retardation assay similar to the vitellogenin gene ERE.
(6) The two polypeptides are different as judged by peptide mapping, and only the 85-kDa polypeptide can be cross-linked to the bromodeoxyuridine-substituted synthetic ERE by UV irradiation.
(7) Two methods have been suggested for the calculation of pHapp and the loss of activity on particle preparation, these methods are based on the use of the ERE in conjunction with experimental data.
(8) These results suggest that the ability of ER and TR to functionally discriminate between an ERE and a TRE is a result of dimerization of their DBDs.
(9) The presence of the biologically active hER is confirmed in co-injection experiments, in which HEO is co-introduced with a CAT reporter gene under the control of a vitellogenin promoter containing or lacking the ERE.
(10) Gene transfer experiments using estrogen-responsive cells have shown that the 13 bp perfect palindromic element GGTCACTGTGACC found upstream of the Xenopus laevis vitellogenin gene A2 promoter mediates hormonal stimulation and thus, was called the estrogen-responsive element (ERE).
(11) The ovalbumin promoter half-palindromic ERE motif located close to the TATA box was required for the activity of the distal DH3 ERE, but could be replaced by the binding sites of other transactivators.
(12) The equilibrium constant for the redox equilibration of fatty acid synthase in a glutathione redox buffer is 15 mM (Ered + GSSG in equilibrium Eox + 2GSH).
(13) When sequenced, these elements showed remarkable diversity and were different from the consensus vitellogenin A2 ERE.
(14) However at 32 degrees C Ta, there was an increase in rectal temperature in response to haloperidol application; this hyperthermia was due to a decrease in both the ear blood flow and respiratory evaporative heat loss (Eres).
(15) The affinity of estradiol binding to receptors was reduced only 2- and 5-fold, respectively, in the double and quadruple Cys to Ala mutants, and estradiol was an effective stimulator of transcription from an estrogen-responsive reporter gene [(ERE)2-TATA-CAT].
(16) A stimulatory estrogen response element (ERE) was localized to a 32-bp region between -547 and -516 bp.
(17) In these genes, two ERE homologues, which have only low, if any, regulatory capacity on their own, act synergistically to achieve high estrogen inducibility.
(18) "Gnnmph, I can't 'ave it 'ere, I 'aven't 'ad my enema," wails a labouring housewife, straining fruitlessly on a communal tenement bog as horrified neighbours look on in their rollers.
(19) This ERE also mediated down-regulation by progestins in the presence of the progesterone receptor, even though it has no progesterone receptor binding ability.
(20) This 67 bp region contains a consensus for the core sequence of the glucocorticoid responsive element (GRE) and the estrogen responsive element (ERE).
Err
Definition:
(v. i.) To wander; to roam; to stray.
(v. i.) To deviate from the true course; to miss the thing aimed at.
(v. i.) To miss intellectual truth; to fall into error; to mistake in judgment or opinion; to be mistaken.
(v. i.) To deviate morally from the right way; to go astray, in a figurative sense; to do wrong; to sin.
(v. i.) To offend, as by erring.
Example Sentences:
(1) But isn't it better to err on the side of caution and start emoting more?
(2) We take the health of our performers very seriously and felt that it was better to err on the side of caution while we determine whether anyone else may have been exposed."
(3) A given diver was reasonably consistent in the direction of his error from one trial to another and from one maneuver to another, although about half the divers tended to err to the right and half to the left.
(4) Antony Altbeker, author of Fruit of a Poisoned Tree, about a miscarriage of justice, said: "Society should err on the side of giving bail to the accused.
(5) But O'Cathain and colleagues say it is perhaps inevitable that call handlers without medical training will err on the side of caution and send people to seek emergency care.
(6) "Err on the side of the [New York] Times, not xoJane ."
(7) All submammalian vertebrates have extraretinal photoreceptors (ERR) that can mediate entrainment of circadian rhythms to 24-h light-dark (LD) cycles.
(8) So this review of the Keynote news will err on the side of optimism.
(9) When localizing tones, however, the barn owl errs in a manner that suggests that it is confused by phantom targets.
(10) to rats for 5 days, indole-3-carbinol was a potent inducer of hepatic ERR deethylation and cytochrome P-450 activity, but had much less effect in the intestine.
(11) The PRC for ONX lizards (only ERRs present) shows a threefold increase in the amplitude of both the advance and delay portions of the PRC compared with a PRC previously generated for sighted S. occidentalis.
(12) This synchronizing system is functionally coupled with the olfactory generator of electrographic respiratory response (ERR), which is brought into activity by nasal air flow.
(13) Thus, immunosuppressive regimens used in cardiac transplant programs tend to err (if they err) on the side of heavier suppression and accept the consequences of this choice.
(14) Unexpectedly, the majority of in vivo ermA transcripts detected were only 245 nt long, suggesting that expression of ErR may be regulated post-transcriptionally.
(15) Humans consistently err in their percepts of rotational motion viewed through an aperture.
(16) While both adults and children err on the 'place of articulation' feature most often, and 'nasality' least often, children produce 'voicing' feature errors less often than adults do, indicating that voicing may be a more important organizing principle for young children than for adults.
(17) "Err no, every right thinking person wants their own team to win, not the best team to win, weirdo.
(18) In my judgment, the Court errs egregiously by overriding Congress’ decision.
(19) Scanning electron microscopy morphometric analysis found major evidence of ERR in the tooth-borne jackscrew appliance, in the long-term group, in the maxillary premolars, on the buccal and furcation root surfaces, on the mesiobuccal root, and in the apical zone.
(20) Concomitantly with splenomegaly, ERR gene expression in spleen cells increases dramatically.