(v. t.) To lap or lay in plaits or folds; to lay one part over another part of; to double; as, to fold cloth; to fold a letter.
(v. t.) To double or lay together, as the arms or the hands; as, he folds his arms in despair.
(v. t.) To inclose within folds or plaitings; to envelop; to infold; to clasp; to embrace.
(v. t.) To cover or wrap up; to conceal.
(v. i.) To become folded, plaited, or doubled; to close over another of the same kind; to double together; as, the leaves of the door fold.
(v.) A doubling,esp. of any flexible substance; a part laid over on another part; a plait; a plication.
(v.) Times or repetitions; -- used with numerals, chiefly in composition, to denote multiplication or increase in a geometrical ratio, the doubling, tripling, etc., of anything; as, fourfold, four times, increased in a quadruple ratio, multiplied by four.
(v.) That which is folded together, or which infolds or envelops; embrace.
(n.) An inclosure for sheep; a sheep pen.
(n.) A flock of sheep; figuratively, the Church or a church; as, Christ's fold.
(n.) A boundary; a limit.
(v. t.) To confine in a fold, as sheep.
(v. i.) To confine sheep in a fold.
Example Sentences:
(1) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(2) 5-Azacytidine (I) stability was increased approximately 10-fold over its stability in water or lactated Ringer injection by the addition of excess sodium bisulfite and the maintenance of pH approximately 2.5.
(3) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(4) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
(5) The DNA untwisting enzyme has been purified approximately 300-fold from rat liver nuclei.
(6) IP3 increased 1.7-fold and IP2 1.6-fold after 20 and 40 s, respectively.
(7) Short incubations with heparin (5 min) caused a release of the enzyme into the media, while longer incubations caused a 2-8-fold increase in net lipoprotein lipase secretion which was maximal after 2-16 h depending on cell type, and persisted for 24 h. The effect of heparin was dose-dependent and specific (it was not duplicated by other glycosaminoglycans).
(8) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(9) Epicanthal folds were present in 46%, mongoloid slanting of the lids in 72% of cases.
(10) The estimated DNA compaction ratio (approximately 3-fold) is consistent with a significant degree of nucleosome unfolding in the hyperstimulated BR genes.
(11) Two hours after refeeding rats fasted for 48 h, ODC activity increased 40-fold in mucosa from the intact jejunum and 4-fold in the mucosa of the bypassed segments.
(12) Transfection of the treated DNA into SOS-induced spheroplasts results in an increase in mutagenesis as great as 50-fold.
(13) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
(14) In strains completely deleted for galR, the gene which encodes the Gal repressor, the operon is derepressed by only 10-fold without an inducer.
(15) The amount of water, creatinine, electrolytes, proteins, and enzymes were higher during the day (up to three fold, p always less than 0.05), while equal amounts of amino acids were excreted in the day and the night period.
(16) TNBS reacts to an extremely small extend with hemoglobin over the concentration range 0.4 to 4 mM whereas FDNB reacts with hemoglobin to a very large extent (50 fold more than TNBS).
(17) Rates of PC in vitro metabolism by liver and kidney cytosolic cysteine conjugate beta-lyases (beta-lyases) were similar, but metabolism by renal mitochondrial beta-lyase occurred at a 3-fold higher rate than the rate obtained with hepatic mitochondrial beta-lyase.
(18) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(19) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(20) The gene, which is located at chromosome XIII, is transcribed as a mRNA of about 2.7 kilobases, and the amount of message has been found to increase 3- to 4-fold during the culture.
Fond
Definition:
() imp. of Find. Found.
(superl.) Foolish; silly; simple; weak.
(superl.) Foolishly tender and loving; weakly indulgent; over-affectionate.
(superl.) Affectionate; loving; tender; -- in a good sense; as, a fond mother or wife.
(superl.) Loving; much pleased; affectionately regardful, indulgent, or desirous; longing or yearning; -- followed by of (formerly also by on).
(superl.) Doted on; regarded with affection.
(superl.) Trifling; valued by folly; trivial.
(v. t.) To caress; to fondle.
(v. i.) To be fond; to dote.
Example Sentences:
(1) People have grown very fond of the first and fifth amendments,” she reports.
(2) But the large sums that undercut Hillary’s sudden fondness for economic populism will undercut Biden just as much, especially if raised conspicuously quickly.
(3) The original Wednesday Play, succeeded by the long-running Play for Today, is fondly remembered by many of today's best-known writers and directors as the experimental breeding ground for the likes of Dennis Potter, Ken Loach, Tony Garnett, Mike Leigh and Alan Bleasdale.
(4) Bomb them,” we tell Pakistan’s army, “crush them, hit them with all you have got.” Taliban were very fond of showing us videos of them killing us.
(5) I thought: this is a country of law and they will help me get my rights.” She is so fond of the child she looked after for 18 months that she feels ambivalent about any possible prosecution of the parents, her ex-employers.
(6) Another person fondly remembered childhood bed-times when she was comforted by Bournvita.
(7) The near-freebie prices amount to an especially generous giveaway to Venezuelans fond of large SUVs and gas-guzzling jalopies from the 1970s and 80s.
(8) John Londesborough Helsinki, Finland • We Finns are delighted to learn that Michael Booth is fond of us and would like us to rule the world.
(9) Since becoming Denmark's first female prime minister two years ago, Thorning-Schmidt has had to contend with the media nickname of "Gucci Helle", so called because of her fondness for designer clothes.
(10) "I have a fond memory of sitting in one of the dressing rooms, talking about Ireland in the 80s, and her showing me as many of her shamrock tattoos as possible.
(11) You are fond of citing the views of "the employers", along with horror stories about the significance of the international tables we're slipping down.
(12) As evidence of this new-found fondness, the album features a guest appearance from a local Salvation Army band.
(13) When France put an end to capital punishment in 1981, it also bid a not-so-fond farewell to the instrument of death that had taken the lives of thousands.
(14) But it clashed with other things.” Asked what his reaction would be now, he said: “I’d jump at it.” Blessed – who is also fondly remembered for another sci-fi role, appearing as Prince Vultan in the movie Flash Gordon – appeared to be a little confused about the Doctor’s surname, inaccurately suggesting the “Who” of the title was actually the character.
(15) He is fond of recalling what the late Labour leader John Smith told him the last time he appeared on his show - "You have a way of asking beguiling questions with potentially lethal consequences."
(16) If I'm extremely fond of a woman, if I think I might really wind up walking down the aisle again… I go in another direction."
(17) His knowledge of movies is vast – all kinds of movies, and I remember that he had a special fondness for genre pictures and for the work of Walter Hill and others – and he has always been very generous about sharing it with his readers.
(18) These films, of which the British are properly fond and proud, were made possible by a Frenchified Brazilian and the son of recent Jewish immigrants from eastern Europe.
(19) Previous chancellor Gordon Brown was fond of his fiscal "golden rule", but the only real golden rule of modern chancellors is never, ever raise the standard rate of income tax.
(20) His father, who was fond of humming the popular ballad Keep Right on to the End of the Road, lost his job in the great depression of the early 1930s.