(v. t.) To rub; to wear away by friction; to chafe; to gall; hence, to eat away; to gnaw; as, to fret cloth; to fret a piece of gold or other metal; a worm frets the plants of a ship.
(v. t.) To impair; to wear away; to diminish.
(v. t.) To make rough, agitate, or disturb; to cause to ripple; as, to fret the surface of water.
(v. t.) To tease; to irritate; to vex.
(v. i.) To be worn away; to chafe; to fray; as, a wristband frets on the edges.
(v. i.) To eat in; to make way by corrosion.
(v. i.) To be agitated; to be in violent commotion; to rankle; as, rancor frets in the malignant breast.
(v. i.) To be vexed; to be chafed or irritated; to be angry; to utter peevish expressions.
(n.) The agitation of the surface of a fluid by fermentation or other cause; a rippling on the surface of water.
(n.) Agitation of mind marked by complaint and impatience; disturbance of temper; irritation; as, he keeps his mind in a continual fret.
(n.) Herpes; tetter.
(n.) The worn sides of river banks, where ores, or stones containing them, accumulate by being washed down from the hills, and thus indicate to the miners the locality of the veins.
(v. t.) To ornament with raised work; to variegate; to diversify.
(n.) Ornamental work in relief, as carving or embossing. See Fretwork.
(n.) An ornament consisting of smmall fillets or slats intersecting each other or bent at right angles, as in classical designs, or at obilique angles, as often in Oriental art.
(n.) The reticulated headdress or net, made of gold or silver wire, in which ladies in the Middle Ages confined their hair.
(n.) A saltire interlaced with a mascle.
(n.) A short piece of wire, or other material fixed across the finger board of a guitar or a similar instrument, to indicate where the finger is to be placed.
(v. t.) To furnish with frets, as an instrument of music.
Example Sentences:
(1) The FSA was fretting about solvency when liquidity was the problem.
(2) She finds indoor activities to discourage the kids from playing outside on the foulest days, and plans holidays abroad as often as possible – but still frets about what their years in Delhi may do to her children’s health.
(3) It might seem absurd, but she also fretted about the horrendous poll tax bills received by people she knew, people she knew couldn't pay.
(4) And in a broader sense, the sort of Conservatives who think intelligently and strategically – and there are more of them than you think – fret that a bearded 66-year-old socialist has ignited political debate in a way that absolutely nobody in the mainstream predicted.
(5) It certainly saved her fretting over her debut sex scene.
(6) Moyes had already described how he had fretted about his attire when Ferguson initially invited him round to discuss the biggest job in English football and how the colour had drained from his face when he was offered it.
(7) For long periods Argentina had been stifled by a fine counterpunching opposition, but it would be a little hasty to fret too much about them after this performance.
(8) Chipmaker ARM is the biggest faller in London, as analysts fret about a slowdown in royalty revenues.
(9) "I used to be really nervous and sit in my dressing room and fret about a scene," he told Rolling Stone .
(10) Hewitt, playing in probably his last Davis Cup for his country at 34 before retiring from the game at the Australian Open in January, added: “We were able to keep Andy out there for a long time, but he’s still favourite [on Sunday].” For the British team, the Murrays’ win lifted a considerable weight off the shoulders of the captain, Leon Smith, who shared the crowd’s anxiety at several key moments of the match, none more fretful than when Andy Murray failed to serve it out in the fourth set and then when they were unable to convert the first match point in the subsequent tie-break.
(11) While Victorians celebrated the empire on which the sun would never set with successive jubilees (golden, 1887, and diamond, 1897), many readers fretted over foreign (increasingly German) threats to the harmony of English life.
(12) On Tuesday, for every wealthy Kolonaki resident fretting about their cash, there was a less well-off state or company employee convinced it would not come to that.
(13) They fretted as political ambition was given rocket boosters by technology.
(14) But better economic sentiment means more market fretting over the Fed's huge stimulus programme being scaled back.
(15) • Follow the Guardian's World Cup team on Twitter • Sign up to play our daily Fantasy Football game • Stats centre: Get the lowdown on every player • The latest semi-final news, features and more People get fretful.
(16) • Three graphs to stop smartphone fans fretting about market share
(17) After dinner she drove him to the railway station while fretting over leaving her baby son sleeping at home.
(18) Significant differences in the shapes of the cathodic Tafel slopes were also seen with cylinders with different surface conditions, and static versus fretting plates.
(19) Despite their jokey exterior, most had big things on their mind, fretting over marriages and babies, breakups and single life; less "grossout" comedy than "freakout".
(20) City analysts still fret that Bailey has either taken on too much or is an unproven chief executive.
Ire
Definition:
(n.) Anger; wrath.
Example Sentences:
(1) An insulin response element (IRE) has been identified in the prolactin gene using chimeric plasmids in which prolactin promoter DNA directs expression of the bacterial chloramphenicol acetyltransferase gene.
(2) The lability of the Fe-S cluster in mitochondrial aconitase has led us to propose that the mechanism by which iron levels are sensed by the IRE-BP involves changes in an Fe-S cluster in the IRE-BP.
(3) Government officials drew the public’s ire after charging Manning with three counts of misconduct following the suicide attempt, including two which carried possible penalties of indefinite solitary confinement.
(4) In a prospective, blinded trial, 40 healthy adult subjects using six IRED thermometers with two techniques were examined in random sequence.
(5) On Wednesday, the ire of the marchers was focused on all those Lib Dems who blithely signed the NUS's anti-fees pledge ("I pledge to vote against any increase in fees in the next parliament and to pressure the government to introduce a fairer alternative" – yesterday, Nick Clegg limply said that he "should have been more careful" than to put his name to it).
(6) Oleg Sentsov should make new films, not count years in prison.” Facebook Twitter Pinterest Oleg Sentsov sings the Ukrainian national anthem as he is sentenced to 20 years in a Russian penal colony Sentsov attracted the ire of the Russian authorities after helping to organise a campaign protesting at Russia’s occupation and annexation of Crimea in March 2014.
(7) A deletion and reconstitution study was undertaken to address the possibility that regions of the ferritin gene and mRNA other than the IRE may be necessary for the production of the full range of iron regulation.
(8) Her predecessor, Nick Robinson, attracted similar ire by upsetting Scottish nationalists .
(9) Interestingly, the FRP which remains active at a given hemin concentration binds to the IRE with the same high affinity as untreated FRP.
(10) The results strongly suggest that HCV RNA carries an internal ribosome entry site (IRES).
(11) Among the 17 pancreatic cancer patients with elevated IRE, 10 underwent radical resection of the cancer but in none of the five patients with normal serum IRE could radical resection be carried out.
(12) In addition, a poor sequence context around AUG-11 results in increased initiation at one or more downstream AUG codons, indicative of leaky scanning or jumping by the ribosome from AUG-11 mediated by the EMCV IRES.
(13) Amino acid alignments reveal that the IRE-BP is 30% identical to mitochondrial aconitase.
(14) Regulation in both instances is mediated by binding of a cytosolic protein to the IREs.
(15) Binding of the IRE-BP represses ferritin translation and represses degradation of the TfR mRNA.
(16) Yet in doing so it presents an angled mirror-polished cliff face of glass, which has been reflecting the sun straight across into the Lloyds offices across the road – the seminal "inside-out" machine that Rogers designed 30 years earlier – much to the ire of its tenants.
(17) The nations with the highest recorded levels include Colombia, Uganda, Afghanistan, India, Pakistan, Bangladesh and Nepal, with the south Asian countries in particular producing unforgettable images of disfigured women who have been assaulted with acid because they have rejected sexual advances or marriage proposals, or aroused jealousy, or in some way or other inconvenienced the patriarchy and aroused its ire.
(18) Artificial mono- and dicistronic mRNAs were prepared and used to identify the region that carried the IRES.
(19) Two melanotic human melanoma cell lines, IRE 1 and IRE 2, and the lymphoma- and leukaemia-derived cell lines Raji and K 562, were exposed to different concentrations (from 5 X 10(-3) M to 10(-5) M) of phenols, both substrates (s) and non-substrates (ns) of tyrosinase, in the presence or absence of the oxygen-radical-scavenger enzymes superoxide dismutase, catalase and peroxidase.
(20) Afterwards, she was "suddenly beautiful", and though the attention this brought was occasionally useful, mostly it was just a pain in the butt: the tiresome suggestions that she had only got on thanks to her appearance; the hurtful ire of that other great feminist, Betty Friedan, whose loathing of Steinem seemed mostly to be motivated by envy.