(n.) A large door or passageway in the wall of a city, of an inclosed field or place, or of a grand edifice, etc.; also, the movable structure of timber, metal, etc., by which the passage can be closed.
(n.) An opening for passage in any inclosing wall, fence, or barrier; or the suspended framework which closes or opens a passage. Also, figuratively, a means or way of entrance or of exit.
(n.) A door, valve, or other device, for stopping the passage of water through a dam, lock, pipe, etc.
(n.) The places which command the entrances or access; hence, place of vantage; power; might.
(n.) In a lock tumbler, the opening for the stump of the bolt to pass through or into.
(n.) The channel or opening through which metal is poured into the mold; the ingate.
(n.) The waste piece of metal cast in the opening; a sprue or sullage piece.
(v. t.) To supply with a gate.
(v. t.) To punish by requiring to be within the gates at an earlier hour than usual.
(n.) A way; a path; a road; a street (as in Highgate).
(n.) Manner; gait.
Example Sentences:
(1) Modulation of the voltage-gated K+ conductance in T-lymphocytes by substance P was examined.
(2) She said that even as she approached the gates, she was debating with the boy’s father whether to let the first-grader enter.
(3) The Brandenburg Gate was lit up in the colours of the German flag.
(4) The committee is chaired by John Thompson, the board's lead independent director, and includes Microsoft founder and chairman, Bill Gates, as well as other board members Chuck Noski and Steve Luczo.
(5) Right ventricular volumes were determined in 12 patients with different levels of right and left ventricular function by magnetic resonance imaging (MRI) using an ECG gated multisection technique in planes perpendicular to the diastolic position of the interventricular septum.
(6) Britain has been the Gates foundation’s second largest recipient, receiving 25 grants worth $156m since 2003.
(7) A method using selective saturation pulses and gated spin-echo MRI automatically corrects for this motion and thus eliminates misregistration artifact from regional function analysis.
(8) Gated blood pool images were stored in modified left anterior oblique views by the multiple gated method (28 frames per beat) after the in vivo labeling of erythrocytes using 25 mCi 99m-Tc.
(9) Four days after a 5 minute bilateral carotid artery occlusion, receptor autoradiography was performed to measure the binding of [35S]t-butylbicyclophosphorothionate (TBPS) to the GABA-gated chloride channel.
(10) Similar responses were obtained with gated noise bursts and by pauses in a series of clicks.
(11) The estimated forward (k) and backward (1) rate constants are: 2.45 x I05 M-1 s- and 0.23 x 103 s-1, respectively, for k and I for the case when the drug is trapped by both activation and inactivation gates, and 3.58 x 105 M-l s-l and 4.15 x 10-3 S-l for the case when the drug is not trapped.
(12) p-NCS-TBOB should prove useful in electrophysiological and biochemical studies examining the properties of GABA-gated Cl- channels.
(13) The involvement of the endothelium and the role of change in membrane potential are evaluated and lead to the conclusion that pressure and flow effects do not depend exclusively on the release of endothelial factors nor the activation of voltage-gated Ca2+ channels.
(14) Norwich Ownership Delia Smith and her husband Michael Wynn Jones own 53.1% of the club’s shares; deputy chairman Michael Foulger owns approximately 16% Gate receipts £12m Broadcasting and media £70m Catering £4m Commercial & other income £12m Net debt Not stated; £2.7m bank overdraft, no directors’ loans.
(15) This conductance is activated when the cis side is made positive, with an apparent gating charge of 3.
(16) In addition to improved image quality, the characteristics of 99mTc sestamibi allow gated planar or SPECT perfusion images to be obtained.
(17) Perijunctional Na+ channels had the same voltage dependence, gating kinetics and sensitivity to tetrodotoxin as extrajunctional Na+ channels, suggesting that these cells express a single type of Na+ channel.
(18) Charge conservation analysis explicitly includes the gating charge when applied in the laboratory frame.
(19) We found the incorporated channels to be insensitive to calcium and octanol, and in most cases to pH in the range of 5-7, suggesting that either these agents do not interact directly with the junctional channels or that the corresponding gating regions are inactivated during the isolation and reconstitution procedures.
(20) "You could be in an open-world single-player environment where you can go up to a gate and when you enter that base, you're walking into a multiplayer map.
Gre
Definition:
(n.) See Gree, a step.
(n.) See Gree, good will.
Example Sentences:
(1) The data were grouped to determine differences between the experimental and the newly revised formats of the GRE-A measure, in addition to any differences among programs.
(2) However, a purified recombinant fragment of the GR which contained essentially only its DNA binding domain was unable to bind at the GME although it interacted strongly with a consensus GRE sequence.
(3) Although GRE images rapidly demonstrated flow in vascular intracranial lesions as high intensity, the vascular nature of these lesions was also clearly evident on SE images in most cases.
(4) We have used cloned rat glucocorticoid-receptor coding sequences to produce and characterize a novel class of receptor mutants that elicit GRE enhancer function in transfected cells even in the absence of hormone.
(5) The MR appearance of thrombosis of the portal vein and its branches using gradient echo (GRE) sequences is described.
(6) Assuming that function as a GRE reflects binding of glucocorticoid receptor, our activity data are consistent with the recognition of the GRE as two hexamer half-sites, each half-site recognized by a single subunit of a receptor dimer, probably in a cooperative fashion.
(7) The sequence recognition by the glucocorticoid receptor at the different defined glucocorticoid regulatory elements (GRE) is discussed and a consensus sequence formulated.
(8) We found that the promoter is extremely G + C rich (72% GC content) and contains a "TAATA" and a "CAT" box, eight "GGGCGG", three "CCGCCC" and two "CACCC" motifs and a motif similar to the glucocorticoid responsive element (GRE) which included two interchanged nucleotides "TCTTGT".
(9) Gel retardation analysis demonstrates that bacterially expressed c-Jun disrupts GR-GRE complexes.
(10) These results demonstrate the importance of GRE consensus sequences in glucocorticoid receptor interactions with DNA, and further identify a cause for high background binding observed when pBR322 DNA is used as a negative control in studies of glucocorticoid receptor-DNA interactions.
(11) Given the "time of flight" effect of GRE sequences, a scan plane perpendicular to the direction of flow was used to obtain maximal signal enhancement of flowing blood.
(12) All pRagCAT constructs in which the 5'-region contained at least one of the two GRE consensus sequences were stimulated by dexamethasone.
(13) Oversaturation (2.0 mumol Fe for SE sequences, greater than or equal to 1.0 mumol Fe for GRE sequences) led to image distortion and did not allow assessment of lymph node morphology.
(14) To accommodate the observed biphasic dose-response curve for highly specific glucocorticoids, and the shift-to-the-left for both classes of effector, we have proposed a model of a single "turn-on" nuclear acceptor site for glucocorticoid receptors (glucocorticoid regulatory element: GRE) and multiple, pre-emptive "turn-off" GREs, occupancy of any one of which will abrogate transcription; for progestins, we propose that all the GRE are alternate "turn-off" sites.
(15) A moderately repetitive DNA sequence, containing a TATA box, a GRE consensus, a Z-DNA forming sequence and two imperfect direct repeats at the extremities, is present a few nucleotides 5' of the human PAI-1 gene transcription start site, raising the possibility that this gene could have been activated by DNA insertion during evolution.
(16) In vitro transcription experiments using a Xenopus laevis cell-free extract have demonstrated that a DNA fragment containing a glucocorticoid response element (GRE) significantly enhances the expression of a methionine tRNA gene.
(17) R1881-activated transcription of a GRE-tk-CAT reporter gene construct was strongly diminished by both mutant receptors and was only partially restored using a 100-fold higher concentration of ligand compared with wild-type receptor.
(18) New cine GRE imaging techniques provide a noninvasive means for quantification of valvular as well as ventricular function.
(19) To investigate the detection of vascular extension of tumor with the GRE technique, findings in the preoperative GRE MR images of 26 patients with renal adenocarcinoma were compared with findings at surgery and pathologic examination.
(20) Our results demonstrate that in-plane GRE imaging and MR angiography can potentially be used as noninvasive methods for evaluating vascular patency in the presence of MR-compatible endovascular devices.