(a.) Of or belonging to that part or end which is in the rear, or which follows; as, the hinder part of a wagon; the hinder parts of a horse.
(a.) To keep back or behind; to prevent from starting or moving forward; to check; to retard; to obstruct; to bring to a full stop; -- often followed by from; as, an accident hindered the coach; drought hinders the growth of plants; to hinder me from going.
(a.) To prevent or embarrass; to debar; to shut out.
(v. i.) To interpose obstacles or impediments; to be a hindrance.
Example Sentences:
(1) The blocking action may have masked and hindered detection of the stimulatory action of barium in other systems.
(2) Diffusional anisotropy of water protons, induced by nonrandom, directional barriers which hinder or retard water motion, is measurable by MRI.
(3) The power of the landed elite is often cited as a major structural flaw in Pakistani politics – an imbalance that hinders education, social equality and good governance (there is no agricultural tax in Pakistan).
(4) Mapping of susceptibility is hindered by the limitations of conventional tissue typing techniques, and by strong linkage disequilibrium within this part of the genome.
(5) From these results, we presume that light induces a protein that hinders the interaction of gp70 in HM1 cells with its receptor on the NC4 cell surface and thereby inhibits the sexual process between these strains.
(6) This in vivo incorporation of tungsten was competitively hindered by molybdenum.
(7) If a prisoner is in the process of taking a programme this can hinder or even curtail their progress – many prisons don't offer certain programmes so if you are moved to a prison without a particular course you are back to square one when it comes to the crucial Parole Board assessment.
(8) From the outset the former Leicester University economics professor has made no secret of the fact this his “dysfunctional relationship” with Anastasiades and other central Bank board members had hindered his role in the post.
(9) The inhibition of Na+K+ ATPase and Mg2+ ATPase activity which may affect the release and uptake of biogenic amines in CNS, hinders the maturation of human fetal brain.
(10) The identification of patients usually refractory to outpatient treatment was hindered by the constant flux in the population base as illustrated by an 85% increase in the asthma registry over the succeeding 12-mo period.
(11) OKT4 and OKT8 monoclonal antibodies slightly hindered depolarization by CsA while OKT3, OKT11 and OKIa1 antibodies had no such effect.
(12) The Communist party and the liberal Yabloko party complained on Sunday of extensive election violations aimed at boosting United Russia's vote count, including party observers being hindered in their work.
(13) These data indicate that the basic model presented here provides a suitable vehicle for future studies into the biochemical events that may cause skeletal muscle enlargement during resistance training but, based on limited data, suggests that an increased frequency of training days may hinder muscle enlargement in this model.
(14) If this geometry was changed, a decrease in affinity was observed and if the ligand binding was sterically hindered, a spectral shift to a five-coordinated complex absorbing at 390 nm occurred.
(15) Administrative inefficiency hinders even more the appropriate utilization of resources.
(16) Thus, the product of natural processing of equine myoglobin probably has hindering structures in the regions flanking the core epitope 102-118 that interfere with presentation by I-Ak but not I-AS.
(17) Many tropical diseases cause disability and hinder the socio-economic development of the Third World countries where they rage.
(18) The difficulties encountered in casting titanium and its alloys have until recently hindered any widespread use of titanium in restorative dentistry.
(19) Warming water will make it hard for many of the reef’s corals to survive, while the acidification of the oceans will hinder the ability of remaining corals to form their skeletons.
(20) The 3-nitrocatechol-structure of nitecapone seems to hinder nitro-reduction, catechol-O-methylation, and sulfation reactions.
Unfavorable
Definition:
(a.) Not favorable; not propitious; adverse; contrary; discouraging.
Example Sentences:
(1) Recently reported unfavorable clinical results (i.e., a high incidence of pain) have led to the discontinuation of one trial of porous polyethylene.
(2) By treatment of mice with anticancer agent CY or gamma ray irradiation, unfavorable side effects usually occurred to impair hematopoietic organs, causing bone marrow disorder.
(3) From the previously observed results of preferential interactions for salting-out salts with proteins, it was shown that the free energy of the protein is increased by addition of the salts and this unfavorable free energy is smaller for the proteins bound to the columns because of their smaller surface area exposed to solvent; i.e., the bound form of the proteins is thermodynamically more stable.
(4) Fifty percent of patients with the myelodysplastic syndrome, frequently following treatment by radiation or chemotherapy, have prognostically unfavorable deletions of the long arms of chromosomes 5 and 7, or trisomy 8, as have the 25% of patients with acute myeloblastic leukemia where remissions last 6-12 months, and where relapse cannot be prevented.
(5) Since liver metastases are the most common unfavorable outcome of colon cancer, ongoing trials using liver-directed treatment (perfusion, irradiation) should be followed with interest.
(6) Extracorporeal shockwave lithothripsy was very helpful in facilitating extraction of stones in unfavorable locations or located above the severe stricture.
(7) A positive deltaS compensates for an unfavorable positive deltaH so that the overall reaction is exergonic.
(8) The results show that conversion of Glu-208 to Gln greatly enhanced substrate binding, implying that Glu-208 interacts unfavorably with the substrate's ground state, preventing its optimal fit to the active site.
(9) Our data suggest that prostaglandin gel cervical ripening and induction of labor and delivery by 42 weeks' gestation may be the most appropriate management for patients with well-established gestational age and an unfavorable cervical examination.
(10) When patients with and without ST shift on Holter monitor ECG were compared, an unfavorable outcome was found in 48% versus 20% (p less than 0.005), multivessel disease in 76% versus 54% (p less than 0.01) and left main coronary stenosis in 18% versus 4% (p less than 0.05).
(11) Based on a preliminary trial that suggested that CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone), and PVB (cisplatinum, vinblastine, bleomycin), are at least partially non-cross-resistant, the Southwest Oncology Group treated patients with unfavorable histology, non-Hodgkin's lymphoma with CHOP and PVB.
(12) Myocardial transformation, along with its energy economizing effect, failed to compensate for unfavorable energetic consequences of structural dilatation and therefore the reduced ventricular efficiency is assumed to be another deleterious factor in the dilated failing heart.
(13) So far we believe that loss of hearing caused during these operations is mainly due to the unfavorable location of the cochlear blood supply through the meatus.
(14) Hypodiploidy is therefore an unfavorable karyotypic feature in childhood ALL.
(15) Hormone therapy was not indicated in these cases as it could lead to unfavorable results: decreased indices of definitive growth resulting from the formation of antibodies to the growth hormone.
(16) The course of gonarthrosis was unfavorable in that a majority of the cases became worse over the years and some also developed pain at rest.
(17) The favorable effects of up to 25% toasted soybean meal and 3% licorice root extract on the levels of the four enzymes, without unfavorable changes in clinical parameters, might account in part for the chemopreventive activities of these additives.
(18) The following signs in the preoperative radiographs were predictive of unfavorable outcome: small head fragment, comminution of the calcar femorale, and varus angulation of the head.
(19) When Rappaport's classification was used, division of unfavorable histologies into histiocytic and non-histiocytic groups provided only marginal significance in MVA.
(20) The outcome was unfavorable and the response to anticonvulsant drugs was poor.