(a.) Indulging in ease; avoiding labor and exertion; habitually idle; lazy; inactive; as, an indolent man.
(a.) Causing little or no pain or annoyance; as, an indolent tumor.
Example Sentences:
(1) The rate of indole production is increased about 4-fold when the aminoacrylate produced is converted to S-(hydroxyethyl)-L-cysteine by a coupled beta-replacement reaction with beta-mercaptoethanol.
(2) This derivative also allowed sensitive detection and measurement of indole-3-pyruvate in the picogram range using a gas chromatograph with an electron capture detector.
(3) In addition, it has excellent antibacterial activity against indole-positive Proteus strains against which conventional Cephalosporins are ineffective.
(4) These findings imply that smooth muscle replication in advanced plaques is indolent and raise the possibility of a role for proliferating leukocytes.
(5) Mitomycin C extravasation produces a painful indolent ulcer that does not have any tendency to heal.
(6) Among the indoles tested only 6-chloromelatonin, melatonin and N-acetylserotonin had significant affinities to the [125I]iodomelatonin binding site.
(7) Using thin layer chromatography on fluorescent silica gel plates, 5 indoles were identified and 6 unknown substances isolated from the pineal incubate and from both extracts.
(8) It was also found that the levels of s-dTK in the progressive stage were much higher than those in the indolent stage.
(9) Cyclobutadipyrimidines (pyrimidine dimers) undergo splitting that is photosensitized by indole derivatives.
(10) This series of compounds includes [R-(R*,R*)]-4-[[2-[[3-(1H-indol-3-yl)-2-methyl-1-oxo-2- [[(tricyclo[3.3.1.1] dec-2-yloxy)carbonyl]amino]propyl]amino]-1-phenylethyl]amino]- 4-oxobutanoic acid (CI-988, 1, Figure 1), the first rationally designed non-peptide antagonist of a neuropeptide receptor.
(11) Eight of the nine (88.9%) Proteus vulgaris isolates gave a positive spot indole test; one (11.1%) gave a negative result.
(12) 15 human tumour cell lines (lung, breast and colon) have been evaluated for their sensitivity to the quinone based anti-cancer drugs Mitomycin C, Porfiromycin, and EO9 (3-hydroxymethyl-5-aziridinyl-1-methyl-2-(IH-indole-4,7-dione)prop-beta- en-alpha-ol).
(13) The fluorogenic beta-D-Glucuronidase test, together with an Indol-capillary test for rapid identification of E. coli, were proved with 60 toxinogenic, 335 nontoxinogenic wild-type strains, and 87 other gram-negative isolates from food.
(14) Enzymatic production of L-tryptophan from DL-serine and indole by a coupled reaction of tryptophan synthase and amino acid racemase was studied.
(15) It inhibited some Enterobacter and indole-positive Proteus, but it was less active against these later species than was cefamandole, cefuroxime, or cefoxitin.
(16) An hydroxyl group in the 5 position of the indole nucleus, sterically unencumbered by hydroxyls in neighboing positions, is essential.
(17) We now report a second case with similar features of chronic recurrent indolent inflammatory skin lesions, nondiagnostic skin biopsies, and failure to respond to antibiotics.
(18) In this study, the roots of Tabernaemontana heyneana Wall were examined and the isolation and identification of additional indole alkaloids and some pharmacological properties of coronaridine are described.
(19) In an effort to understand the mechanism by which dietary indoles inhibit chemically initiated tumorigenesis in experimental animals, we have investigated the potency of 3-substituted and 1,3-disubstituted indoles on the induction of intestinal and hepatic cytochrome P-448-dependent monooxygenases in the rat.
(20) Low nanogram levels of tyrosine, norepinephrine, 5-hydroxyindole-3-acetic acid, tryptophan, serotonin and 6-hydroxymelatonin, and picogram levels of 5-hydroxytryptophan, 5-hydroxytryptophol, 5-methoxyindole-3-acetic acid, indole 3-acetic acid, 5-methoxytryptophol and melatonin were indicated in most of the samples.
Loll
Definition:
(v. i.) To act lazily or indolently; to recline; to lean; to throw one's self down; to lie at ease.
(v. i.) To hand extended from the mouth, as the tongue of an ox or a log when heated with labor or exertion.
(v. i.) To let the tongue hang from the mouth, as an ox, dog, or other animal, when heated by labor; as, the ox stood lolling in the furrow.
(v. t.) To let hang from the mouth, as the tongue.
Example Sentences:
(1) As our car crawls through central London, from WPP's Mayfair head office to Millbank, where Sorrell is to sit on a panel, the dog sits placidly in the back, lolling its head in the sun.
(2) The conformation of the staphylococcal nuclease-bound metal-dTdA complex, previously determined by NMR methods [Weber, D.J., Mullen, G.P., Mildvan, A.S. (1991) Biochemistry 30:7425-7437] was docked into the X-ray structure of the enzyme-Ca(2+)-3',5'-pdTp complex [Loll, P.J., Lattman, E.E.
(3) A total of loll patients (CP) discharged from an acute medical department (AM) had 1954 readmissions (GI).
(4) During a recent food distribution, a few local guards in blue uniform lolled about, but they leave when it gets dark at 6pm.
(5) Expect to lose a few hours lolling in the hammocks on the verandah, eating fresh mango and melon breakfasts, with friends of the Capela family dropping by for beers in the evening.
(6) It's sunny and beautiful outside, but you can't spend the whole weekend lolling about in the garden wondering if you should light up the barbecue, thereby angering the rain gods into immediate action.
(7) By day, guests loll in the lounge area or sun themselves on the beach, bartering for fresh catch with local fishermen when they return from the sea in the afternoon.
(8) The farmer and his children crowd around; a girl of seven or eight stirs a pot on an open fire and, in the dust, chickens fight over the entrails of a ram left over from Eid, its head still lolling in the dirt.
(9) A couple of minutes later the farmer comes skidding around the corner with his gun on his shoulder and a small, dead deer lolling over the back end of his quad bike.
(10) He lolls back in his chair, sometimes waving his arms around erratically.
(11) Prosecutors displayed an enlarged version of one of the images that was successfully retrieved from a witness's mobile phone – the now-infamous picture of the girl being carried by the defendants by her hands and feet, with her head apparently lolling backwards.
(12) She appeared unconscious, her head lolling at an awkward angle, brown stains down her left leg.
(13) Weakness and atrophy of neck muscles, and lolling of the neck have also been described.
(14) Leave time for a meal in the grounds at the idyllic Lodi restaurant, where you can loll in a private gypsy wagon overlooking a sun-dappled courtyard, sip cocktails and work your way through the delicious Mediterranean menu.
(15) U.S.A. 76, 2551-2555; Loll, P. J., & Lattman, E. E. (1989) Proteins: Struct., Funct., Genet.
(16) He's got special dispensation to drop to the bench, and loll on it, if his warm-up doesn't go well.
(17) The other day a guy was sawing a lamb carcass in half; it was mainly hollowed out apart from the kidneys, which were lolling about uselessly like glistening brown eggs, while the anchor monotonously droned on about traces of phenylbutazone .
(18) The undeserving poor drink White Lightning in the daytime, have too many children, keep dangerous dogs and spend their lives lolling about on the sofa.
(19) A dead pig lolls among the flotsam on South Tarawa beach.
(20) The high-resolution X-ray structure of wild-type staphylococcal nuclease (E43 SNase) suggests that Glu 43 acts a general basic catalyst to assist the attack of water on a phosphodiester substrate [Loll, P., & Lattman, E. E. (1989) Proteins: Struct., Funct., Genet.